Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL020C
Length:
531
Number of sequences:
5887
Description:
YDL020C RPN4 SGDID:S000002178, Chr IV from 416708-415113, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P43301    387   EGR3_RAT Early growth response protein 3 OS=R...780.22     37.7     35     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32P43300    387   EGR3_MOUSE Early growth response protein 3 OS...780.22     37.7     35     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33Q06889    387   EGR3_HUMAN Early growth response protein 3 OS...780.22     37.7     35     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IMP:BHF-UCL.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0007623; P:circadian rhythm; TAS:ProtInc.::GO:0035767; P:endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34A4II20    498   EGR1_XENTR Early growth response protein 1 OS...580.28     37.4     41     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35Q6GQH4    497   EGR1A_XENLA Early growth response protein 1-A...580.29     37.4     41     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36O73694    59   EGR1_SERCA Early growth response protein 1 OS...560.3     34.7     41     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:AgBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:AgBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37P78871    567   RST2_SCHPO Zinc finger protein rst2 OS=Schizo...1023.4     34.3     32     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031670; P:cellular response to nutrient; IDA:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IDA:PomBase.::GO:0051039; P:positive regulation of transcription during meiosis; IDA:PomBase.::GO:0006111; P:regulation of gluconeogenesis; IDA:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38P18146    543   EGR1_HUMAN Early growth response protein 1 OS...580.31     37.4     41     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0033233; P:regulation of protein sumoylation; IDA:BHF-UCL.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
39P08046    533   EGR1_MOUSE Early growth response protein 1 OS...580.33     37.4     41     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:MGI.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0032868; P:response to insulin stimulus; IDA:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:MGI.
40P26635    62   EGR2_POERE Early growth response protein 2 OS...580.34     34.7     41     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41P08154    508   EGR1_RAT Early growth response protein 1 OS=R...580.34     37.4     41     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:RGD.::GO:0008134; F:transcription factor binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0035690; P:cellular response to drug; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071504; P:cellular response to heparin; IDA:UniProtKB.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071317; P:cellular response to isoquinoline alkaloid; IEP:RGD.::GO:0071260; P:cellular response to mechanical stimulus; IEP:RGD.::GO:0071506; P:cellular response to mycophenolic acid; IDA:UniProtKB.::GO:0071383; P:cellular response to steroid hormone stimulus; IEP:RGD.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0072110; P:glomerular mesangial cell proliferation; IMP:UniProtKB.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0060291; P:long-term synaptic potentiation; IEP:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; IMP:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.::GO:0001975; P:response to amphetamine; IEP:RGD.::GO:0034465; P:response to carbon monoxide; IEP:RGD.::GO:0042220; P:response to cocaine; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0071873; P:response to norepinephrine stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.
42P26632    511   EGR1_DANRE Early growth response protein 1 OS...780.34     37.4     35     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q6NTY6    475   EGR1B_XENLA Early growth response protein 1-B...580.37     37     41     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44Q9EPW2    415   KLF15_MOUSE Krueppel-like factor 15 OS=Mus mu...1050.4     37     30     45
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45Q0P4W9    462   FEZF1_XENTR Fez family zinc finger protein 1 ...1290.45     37     28     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q9NYW8    714   RBAK_HUMAN RB-associated KRAB zinc finger pro...1420.56     36.6     29     39GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0045892; P:negative regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47Q8TD94    323   KLF14_HUMAN Krueppel-like factor 14 OS=Homo s...1130.62     36.2     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48A1XSY8    471   EGR2_PIG E3 SUMO-protein ligase EGR2 OS=Sus s...780.63     36.2     35     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006611; P:protein export from nucleus; ISS:UniProtKB.
49O93567    546   ZBT7A_CHICK Zinc finger and BTB domain-contai...550.68     36.2     36     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50Q6BEB4    398   SP5_HUMAN Transcription factor Sp5 OS=Homo sa...710.68     36.2     32     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51P0CG23    659   ZN853_HUMAN Zinc finger protein 853 OS=Homo s...330.69     36.6     55     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
52Q3U3I9    1058   ZN865_MOUSE Zinc finger protein 865 OS=Mus mu...1650.7     36.6     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53Q9JHX2    398   SP5_MOUSE Transcription factor Sp5 OS=Mus mus...710.72     36.2     32     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060349; P:bone morphogenesis; IGI:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035121; P:tail morphogenesis; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54Q03081    177   MET31_YEAST Transcriptional regulator MET31 O...880.73     35     32     44GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031335; P:regulation of sulfur amino acid metabolic process; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q19A41    325   KLF14_MOUSE Krueppel-like factor 14 OS=Mus mu...1040.75     35.8     27     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56Q6ZMV8    503   ZN730_HUMAN Putative zinc finger protein 730 ...550.75     36.2     42     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57Q19A40    323   KLF14_PANTR Krueppel-like factor 14 OS=Pan tr...1130.76     35.8     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q14V87    323   KLF14_GORGO Krueppel-like factor 14 OS=Gorill...1130.76     35.8     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59Q91X45    518   ZBTB3_MOUSE Zinc finger and BTB domain-contai...630.77     36.2     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60P26634    62   EGR2_CERTH E3 SUMO-protein ligase EGR2 OS=Cer...580.82     33.5     40     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61P39956    796   RPH1_YEAST DNA damage-responsive transcriptio...750.82     36.2     28     45GO:0005634; C:nucleus; IC:SGD.
GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:SGD.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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