Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q96JA3    519   PKHA8_HUMAN Pleckstrin homology domain-contai...1220.0000003     58.5     30     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0051861; F:glycolipid binding; IEA:InterPro.::GO:0017089; F:glycolipid transporter activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
62Q54RM1    422   OSB7_DICDI Oxysterol-binding protein 7 OS=Dic...1260.0000004     57.4     33     52
63P35843    434   HES1_YEAST Protein HES1 OS=Saccharomyces cere...3160.0000005     57.4     23     39
GO:0008142; F:oxysterol binding; IDA:SGD.::GO:0015248; F:sterol transporter activity; IDA:SGD.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
64Q8MPQ7    389   OSB1_DICDI Oxysterol-binding protein 1 OS=Dic...1360.0000007     56.6     30     50GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:dictyBase.::GO:0005625; C:soluble fraction; IDA:dictyBase.
GO:0005515; F:protein binding; IPI:dictyBase.
GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0008202; P:steroid metabolic process; ISS:dictyBase.
65Q9LVD4    379   ORP4C_ARATH Oxysterol-binding protein-related...2750.000003     54.7     25     43
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
66Q86HV4    439   OSB6_DICDI Oxysterol-binding protein 6 OS=Dic...1420.000005     53.9     28     44
67Q9H2K2    1166   TNKS2_HUMAN Tankyrase-2 OS=Homo sapiens (Huma...1570.46     38.5     24     41GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IC:BHF-UCL.::GO:0005635; C:nuclear envelope; IDA:BHF-UCL.::GO:0000242; C:pericentriolar material; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
68Q3UES3    1166   TNKS2_MOUSE Tankyrase-2 OS=Mus musculus (Mous...1570.42     38.9     24     41GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
69Q6P3Q6    617   C43BP_XENTR Collagen type IV alpha-3-binding ...980.00002     52.8     30     52GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
70Q9EQG9    624   C43BP_MOUSE Collagen type IV alpha-3-binding ...980.00003     52     31     52GO:0005829; C:cytosol; IDA:MGI.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0016301; F:kinase activity; IDA:MGI.
GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006672; P:ceramide metabolic process; IMP:MGI.::GO:0007029; P:endoplasmic reticulum organization; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0055088; P:lipid homeostasis; IMP:MGI.::GO:0070584; P:mitochondrion morphogenesis; IMP:MGI.::GO:0006936; P:muscle contraction; IMP:MGI.::GO:0034976; P:response to endoplasmic reticulum stress; IMP:MGI.::GO:0007165; P:signal transduction; IMP:MGI.
71Q5R6M6    624   C43BP_PONAB Collagen type IV alpha-3-binding ...980.00003     52     30     52GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
72Q9Y5P4    624   C43BP_HUMAN Collagen type IV alpha-3-binding ...980.00003     52     30     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0097001; F:ceramide binding; IDA:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; TAS:ProtInc.
GO:0035621; P:ER to Golgi ceramide transport; IGI:UniProtKB.::GO:0006955; P:immune response; NAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
73Q6VVX2    598   C43BP_CRIGR Collagen type IV alpha-3-binding ...980.00004     51.6     30     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
GO:0035621; P:ER to Golgi ceramide transport; IMP:UniProtKB.
74Q9GKI7    624   C43BP_BOVIN Collagen type IV alpha-3-binding ...980.00004     51.6     30     52GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
75O94512    516   OBP1_SCHPO Oxysterol-binding protein-like pro...2890.00008     50.4     22     35GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
GO:0008142; F:oxysterol binding; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0030100; P:regulation of endocytosis; ISS:PomBase.
76A5PMU4    1280   ANS1B_DANRE Ankyrin repeat and sterile alpha ...2000.0001     50.4     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
77Q9XZC0    1413   LCTA_LATTR Alpha-latrocrustotoxin-Lt1a OS=(La...2250.012     43.9     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
78Q6NRZ4    617   C43BP_XENLA Collagen type IV alpha-3-binding ...980.0002     49.3     29     51GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
79Q05753    435   AKRP_ARATH Ankyrin repeat domain-containing p...900.0002     48.9     34     49GO:0009507; C:chloroplast; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
80Q5M7Y0    620   C43BP_DANRE Collagen type IV alpha-3-binding ...900.0003     48.9     29     52GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
81P98150    906   NFKB2_CHICK Nuclear factor NF-kappa-B p100 su...1980.0003     49.3     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82Q8VHK2    1430   CSKI1_RAT Caskin-1 OS=Rattus norvegicus (Rat)...1610.0003     49.3     27     43GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019904; F:protein domain specific binding; IDA:RGD.
GO:0007165; P:signal transduction; IPI:UniProtKB.
83O95271    1327   TNKS1_HUMAN Tankyrase-1 OS=Homo sapiens (Huma...1760.01     44.3     24     43GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; TAS:BHF-UCL.::GO:0005643; C:nuclear pore; TAS:BHF-UCL.::GO:0000242; C:pericentriolar material; TAS:BHF-UCL.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0070212; P:protein poly-ADP-ribosylation; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; TAS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
84Q3V096    527   ANR42_MOUSE Ankyrin repeat domain-containing ...560.052     41.6     38     66GO:0005634; C:nucleus; IDA:MGI.
GO:0051059; F:NF-kappaB binding; IPI:MGI.
GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IMP:MGI.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:MGI.
85Q6PFX9    1320   TNKS1_MOUSE Tankyrase-1 OS=Mus musculus (Mous...1760.011     43.9     24     43GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
86Q8WXD9    1431   CSKI1_HUMAN Caskin-1 OS=Homo sapiens (Human)....1550.0005     48.5     28     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0007165; P:signal transduction; ISS:UniProtKB.
87Q6P9K8    1431   CSKI1_MOUSE Caskin-1 OS=Mus musculus (Mouse)....1610.0005     48.5     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
88Q8BIZ1    1259   ANS1B_MOUSE Ankyrin repeat and sterile alpha ...1940.0006     48.1     26     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
89Q8N9B4    389   ANR42_HUMAN Ankyrin repeat domain-containing ...571.4     36.6     32     67
90Q4R3S3    262   ANKR7_MACFA Ankyrin repeat domain-containing ...1760.001     46.2     26     45
91P0C6S7    1260   ANS1B_RAT Ankyrin repeat and sterile alpha mo...1600.001     47     26     47GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
records
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