Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P38713    996   OSH3_YEAST Oxysterol-binding protein homolog ...4381e-40     167     29     47GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.
GO:0005545; F:1-phosphatidylinositol binding; ISS:SGD.::GO:0008142; F:oxysterol binding; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015248; F:sterol transporter activity; IDA:SGD.
GO:0001403; P:invasive growth in response to glucose limitation; IGI:SGD.::GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IGI:SGD.::GO:0010922; P:positive regulation of phosphatase activity; IDA:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.
32Q9UW25    433   OBPA_CANAL Oxysterol-binding protein-like pro...3493e-25     114     29     44
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0044011; P:single-species biofilm formation on inanimate substrate; IMP:CGD.
33Q9H0X9    879   OSBL5_HUMAN Oxysterol-binding protein-related...3792e-23     111     27     44GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008142; F:oxysterol binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.::GO:0030301; P:cholesterol transport; NAS:UniProtKB.::GO:0006893; P:Golgi to plasma membrane transport; NAS:UniProtKB.
34Q02201    448   OSH6_YEAST Oxysterol-binding protein homolog ...3545e-23     107     28     45GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0008142; F:oxysterol binding; ISS:SGD.::GO:0070300; F:phosphatidic acid binding; IDA:SGD.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:SGD.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0055092; P:sterol homeostasis; IMP:SGD.::GO:0016125; P:sterol metabolic process; IGI:SGD.
35Q9UW21    429   OBPAL_CANAL Oxysterol-binding protein-like pr...3519e-23     106     27     44
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
36Q9BZF1    889   OSBL8_HUMAN Oxysterol-binding protein-related...3753e-22     107     27     45
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
37P38755    437   OSH7_YEAST Oxysterol-binding protein homolog ...3646e-22     103     27     44GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0008142; F:oxysterol binding; ISS:SGD.
GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IGI:SGD.
38Q9ER64    874   OSBL5_MOUSE Oxysterol-binding protein-related...2511e-20     102     29     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
39Q86KG4    466   OSB4_DICDI Oxysterol-binding protein 4 OS=Dic...3693e-19     96.3     24     42
40Q9UUA1    489   YJX1_SCHPO Oxysterol-binding protein homolog ...3763e-19     96.3     25     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008142; F:oxysterol binding; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
41Q9BXB5    764   OSB10_HUMAN Oxysterol-binding protein-related...3070.056     41.6     25     40
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
42Q0IJ05    739   OSBL9_XENTR Oxysterol-binding protein-related...960.008     44.3     28     48
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
43A2A8Z1    736   OSBL9_MOUSE Oxysterol-binding protein-related...960.01     43.9     28     48
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
44Q96SU4    736   OSBL9_HUMAN Oxysterol-binding protein-related...960.009     43.9     28     48
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
45Q54NM4    390   OSB10_DICDI Oxysterol-binding protein 10 OS=D...3710.000000000000002     83.6     23     41
46Q5R9W4    736   OSBL9_PONAB Oxysterol-binding protein-related...960.032     42.4     27     47
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
47Q54PS9    428   OSB9_DICDI Oxysterol-binding protein 9 OS=Dic...3450.000000000000003     83.2     27     41
48Q9BXB4    747   OSB11_HUMAN Oxysterol-binding protein-related...910.017     43.1     26     51
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
49Q8CI95    751   OSB11_MOUSE Oxysterol-binding protein-related...1240.013     43.5     27     48
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
50P0C199    383   KES1_USTMA Protein KES1 OS=Ustilago maydis (s...2330.0000000000001     77.8     28     46
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
51O74178    388   KES1_SCHPO Protein kes1 OS=Schizosaccharomyce...3690.00000000005     70.1     25     41GO:0032153; C:cell division site; IDA:PomBase.
GO:0008142; F:oxysterol binding; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.
52Q54EF5    402   OSB12_DICDI Oxysterol-binding protein 12 OS=D...3940.00000000008     69.3     22     39
53O43021    402   YGV7_SCHPO Oxysterol-binding protein homolog ...3740.0000000003     67.4     23     38GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
GO:0008142; F:oxysterol binding; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
54Q9ERS4    297   PKHA3_MOUSE Pleckstrin homology domain-contai...1080.0000000008     65.1     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.
55Q9HB20    300   PKHA3_HUMAN Pleckstrin homology domain-contai...1180.000000001     64.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
56Q5U3N0    549   PKHA8_DANRE Pleckstrin homology domain-contai...1220.000000003     65.1     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051861; F:glycolipid binding; IEA:InterPro.::GO:0017089; F:glycolipid transporter activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
57Q9SVZ9    386   ORP4A_ARATH Oxysterol-binding protein-related...3910.00000001     62.8     25     40
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
58P35844    434   KES1_YEAST Protein KES1 OS=Saccharomyces cere...3080.00000002     62     24     41GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.
GO:0008142; F:oxysterol binding; IPI:SGD.::GO:0070300; F:phosphatidic acid binding; IDA:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IMP:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:SGD.::GO:0015248; F:sterol transporter activity; IDA:SGD.
GO:0010922; P:positive regulation of phosphatase activity; IDA:SGD.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
59Q9SW00    383   ORP4B_ARATH Oxysterol-binding protein-related...3830.00000005     60.5     24     40
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
60Q80W71    519   PKHA8_MOUSE Pleckstrin homology domain-contai...1220.0000002     58.9     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051861; F:glycolipid binding; IEA:InterPro.::GO:0017089; F:glycolipid transporter activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
61Q96JA3    519   PKHA8_HUMAN Pleckstrin homology domain-contai...1220.0000003     58.5     30     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0051861; F:glycolipid binding; IEA:InterPro.::GO:0017089; F:glycolipid transporter activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
records
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