Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271P26041    577   MOES_MOUSE Moesin OS=Mus musculus (Mouse). GN...1283.1     35.8     27     47GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IEA:InterPro.::GO:0031528; C:microvillus membrane; IEA:UniProtKB-SubCell.::GO:0001931; C:uropod; IDA:MGI.
272Q8LSQ2    388   SR43C_ORYSJ Probable signal recognition parti...813.2     35.4     31     49GO:0005634; C:nucleus; IEA:InterPro.::GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
273Q865U8    319   ANKR1_PIG Ankyrin repeat domain-containing pr...523.3     35.4     37     62GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003779; F:actin binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.
274Q8IYU2    909   HACE1_HUMAN E3 ubiquitin-protein ligase HACE1...1553.3     35.8     26     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016601; P:Rac protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
275P08567    350   PLEK_HUMAN Pleckstrin OS=Homo sapiens (Human)...1053.4     35.4     30     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.::GO:0032587; C:ruffle membrane; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; IDA:BHF-UCL.
GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005080; F:protein kinase C binding; IDA:BHF-UCL.
GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.::GO:0030866; P:cortical actin cytoskeleton organization; IDA:BHF-UCL.::GO:0002244; P:hemopoietic progenitor cell differentiation; IEP:BHF-UCL.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IDA:BHF-UCL.::GO:0007229; P:integrin-mediated signaling pathway; IDA:BHF-UCL.::GO:0050849; P:negative regulation of calcium-mediated signaling; NAS:BHF-UCL.::GO:0010920; P:negative regulation of inositol phosphate biosynthetic process; IDA:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; IDA:BHF-UCL.::GO:0070527; P:platelet aggregation; ISS:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0030836; P:positive regulation of actin filament depolymerization; IDA:BHF-UCL.::GO:0010925; P:positive regulation of inositol-polyphosphate 5-phosphatase activity; IDA:BHF-UCL.::GO:0033625; P:positive regulation of integrin activation; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0070528; P:protein kinase C signaling cascade; ISS:BHF-UCL.::GO:0070560; P:protein secretion by platelet; ISS:BHF-UCL.::GO:0060305; P:regulation of cell diameter; IDA:BHF-UCL.::GO:0031529; P:ruffle organization; IDA:BHF-UCL.::GO:0070493; P:thrombin receptor signaling pathway; IDA:BHF-UCL.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:BHF-UCL.
276Q6DGX3    315   ANR54_DANRE Ankyrin repeat domain-containing ...583.8     35     40     59
277Q8BIK4    2055   DOCK9_MOUSE Dedicator of cytokinesis protein ...1003.8     35.8     23     45GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
278B2RU33    542   POTEC_HUMAN POTE ankyrin domain family member...1483.9     35.4     24     43
279Q8XHA1    549   HCP_CLOPE Hydroxylamine reductase OS=Clostrid...1103.9     35.4     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016661; F:oxidoreductase activity, acting on other nitrogenous compounds as donors; IEA:InterPro.
280Q18297    1211   TRPA1_CAEEL Transient receptor potential cati...2054.1     35.4     21     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
281Q9WV71    426   ASB4_MOUSE Ankyrin repeat and SOCS box protei...1934.4     35     25     38GO:0031462; C:Cul2-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0031466; C:Cul5-RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:2001214; P:positive regulation of vasculogenesis; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
282Q4UMH6    1179   Y381_RICFE Putative ankyrin repeat protein RF...2036.2     35     23     42
GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
283Q10728    1032   MYPT1_RAT Protein phosphatase 1 regulatory su...1484.4     35.4     25     47GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB.::GO:0004721; F:phosphoprotein phosphatase activity; IDA:RGD.
GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.
284Q96I34    528   PP16A_HUMAN Protein phosphatase 1 regulatory ...1464.5     35     27     40GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
285Q7TQP6    835   TNI3K_RAT Serine/threonine-protein kinase TNN...1564.5     35.4     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
286Q8GXE6    888   AKT6_ARATH Potassium channel AKT6 OS=Arabidop...1504.5     35.4     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
287Q68LP1    971   MIB2_RAT E3 ubiquitin-protein ligase MIB2 OS=...1964.7     35.4     24     40
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
288Q13418    452   ILK_HUMAN Integrin-linked protein kinase OS=H...704.8     35     34     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
289Q9DBR7    1029   MYPT1_MOUSE Protein phosphatase 1 regulatory ...1484.8     35.4     25     47GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB.
GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; IMP:MGI.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.::GO:0046822; P:regulation of nucleocytoplasmic transport; IMP:MGI.
290P57044    451   ILK_CAVPO Integrin-linked protein kinase OS=C...704.9     35     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
291Q99J82    452   ILK_RAT Integrin-linked protein kinase OS=Rat...705     35     34     56GO:0005911; C:cell-cell junction; IDA:RGD.::GO:0043034; C:costamere; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IDA:RGD.
GO:0007569; P:cell aging; IMP:RGD.::GO:0007050; P:cell cycle arrest; IMP:RGD.::GO:0043206; P:fibril organization; IMP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; IMP:RGD.::GO:0032288; P:myelin assembly; IMP:RGD.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:RGD.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:RGD.
292O55222    452   ILK_MOUSE Integrin-linked protein kinase OS=M...705     35     34     56GO:0005925; C:focal adhesion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:MGI.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
293Q8BG95    976   MYPT2_MOUSE Protein phosphatase 1 regulatory ...666.4     34.7     36     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
294Q5R5V4    452   ILK_PONAB Integrin-linked protein kinase OS=P...705.1     35     34     56GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009966; P:regulation of signal transduction; IEA:InterPro.
295Q3SWY2    452   ILK_BOVIN Integrin-linked protein kinase OS=B...705.1     35     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009966; P:regulation of signal transduction; IEA:InterPro.
296P0CB52    233   NANE_STRSU Putative N-acetylmannosamine-6-pho...1025.3     34.3     28     46
GO:0047465; F:N-acylglucosamine-6-phosphate 2-epimerase activity; IEA:EC.
GO:0006051; P:N-acetylmannosamine metabolic process; IEA:InterPro.
297Q8NFD2    765   ANKK1_HUMAN Ankyrin repeat and protein kinase...1765.5     35     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
298Q86YR6    584   POTED_HUMAN POTE ankyrin domain family member...1485.8     34.7     25     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
299Q9BZ29    2069   DOCK9_HUMAN Dedicator of cytokinesis protein ...865.8     35     22     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007596; P:blood coagulation; TAS:Reactome.
300Q6Q308    351   PLEK_CANFA Pleckstrin OS=Canis familiaris (Do...1065.9     34.7     29     44
301B2RXR6    993   ANR44_MOUSE Serine/threonine-protein phosphat...1606.1     35     26     43
records
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