Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q9Z2F6    448   BCL3_MOUSE B-cell lymphoma 3 protein homolog ...1970.61     37.7     23     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0019730; P:antimicrobial humoral response; IMP:MGI.::GO:0042742; P:defense response to bacterium; IMP:MGI.::GO:0042832; P:defense response to protozoan; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0002268; P:follicular dendritic cell differentiation; IMP:MGI.::GO:0002467; P:germinal center formation; IMP:MGI.::GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0002315; P:marginal zone B cell differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IMP:MGI.::GO:0032729; P:positive regulation of interferon-gamma production; IMP:MGI.::GO:0045082; P:positive regulation of interleukin-10 biosynthetic process; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0048536; P:spleen development; IMP:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI.::GO:0045064; P:T-helper 2 cell differentiation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
212Q8BH49    266   SESQ1_MOUSE Sesquipedalian-1 OS=Mus musculus ...1500.63     37.4     23     39GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
213Q8T2Q0    698   ZDHC6_DICDI Putative ZDHHC-type palmitoyltran...1520.64     38.1     22     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
214Q71S21    1002   INVSB_XENLA Inversin-B OS=Xenopus laevis (Afr...343.9     35.4     44     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
215P53355    1430   DAPK1_HUMAN Death-associated protein kinase 1...620.67     38.1     37     58GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IGI:MGI.::GO:0008624; P:induction of apoptosis by extracellular signals; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
216Q04749    426   AVO2_YEAST Target of rapamycin complex 2 subu...640.67     37.7     30     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0001558; P:regulation of cell growth; IPI:SGD.::GO:0031929; P:TOR signaling cascade; IC:SGD.
217O89019    1062   INVS_MOUSE Inversin OS=Mus musculus (Mouse). ...1503.3     35.8     21     37GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0060971; P:embryonic heart tube left/right pattern formation; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
218Q94CT7    446   XB31_ORYSJ Probable E3 ubiquitin-protein liga...330.81     37.4     45     67
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
219Q5UPF8    879   YL088_MIMIV Putative ankyrin repeat protein L...1860.82     37.7     27     40
220Q9TU71    319   ANKR1_RABIT Ankyrin repeat domain-containing ...494.1     35     37     59
221Q71S22    1007   INVSA_XENLA Inversin-A OS=Xenopus laevis (Afr...343.8     35.4     44     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
222Q4R739    496   ANR53_MACFA Ankyrin repeat domain-containing ...630.83     37.4     33     48
223O35763    577   MOES_RAT Moesin OS=Rattus norvegicus (Rat). G...1280.87     37.4     26     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IEA:InterPro.::GO:0031527; C:filopodium membrane; IDA:RGD.::GO:0009898; C:internal side of plasma membrane; IDA:RGD.::GO:0031528; C:microvillus membrane; IEA:UniProtKB-SubCell.::GO:0030667; C:secretory granule membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0003779; F:actin binding; IDA:RGD.::GO:0030674; F:protein binding, bridging; TAS:RGD.
224Q4V869    286   ACBD6_XENLA Acyl-CoA-binding domain-containin...590.9     37     34     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
225O14974    1030   MYPT1_HUMAN Protein phosphatase 1 regulatory ...1480.92     37.7     26     47GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0043292; C:contractile fiber; IDA:UniProtKB.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0072357; C:PTW/PP1 phosphatase complex; IDA:UniProtKB.
GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.::GO:0019208; F:phosphatase regulator activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:ProtInc.
GO:0051297; P:centrosome organization; IMP:UniProtKB.::GO:0007067; P:mitosis; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.
226Q9KLC1    173   ECTA_VIBCH L-2,4-diaminobutyric acid acetyltr...930.95     36.2     29     44
GO:0033816; F:diaminobutyrate acetyltransferase activity; IEA:EC.::GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
GO:0019491; P:ectoine biosynthetic process; IEA:InterPro.
227Q25338    1214   LITD_LATTR Delta-latroinsectotoxin-Lt1a OS=(L...1630.97     37.7     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
228Q1IWG9    339   DDL_DEIGD D-alanine--D-alanine ligase OS=Dein...490.98     37     43     53GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
229Q1LZC5    299   ANR54_BOVIN Ankyrin repeat domain-containing ...581     37     41     60GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0045648; P:positive regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0010627; P:regulation of intracellular protein kinase cascade; ISS:UniProtKB.
230Q9J502    512   V233_FOWPN Putative ankyrin repeat protein FP...1481     37.4     28     44
231Q8BLA8    1125   TRPA1_MOUSE Transient receptor potential cati...1451.1     37.4     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032421; C:stereocilium bundle; IDA:MGI.
GO:0005262; F:calcium channel activity; IDA:MGI.
GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IDA:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0042493; P:response to drug; IDA:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.::GO:0048265; P:response to pain; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI.
232Q9M8S6    828   SKOR_ARATH Potassium channel SKOR OS=Arabidop...1611.2     37.4     29     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015271; F:outward rectifier potassium channel activity; IDA:TAIR.
233Q5JPF3    1778   AN36C_HUMAN Ankyrin repeat domain-containing ...1531.2     37.4     27     43
GO:0008200; F:ion channel inhibitor activity; NAS:UniProtKB.
234Q92882    214   OSTF1_HUMAN Osteoclast-stimulating factor 1 O...651.2     36.2     28     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
235Q9ULM0    1364   PKHH1_HUMAN Pleckstrin homology domain-contai...1221.2     37.4     26     43GO:0005856; C:cytoskeleton; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.
236Q8Q0U0    360   Y045_METMA Putative ankyrin repeat protein MM...1595     34.7     25     40
237Q6NRK3    813   SWAHB_XENLA Ankyrin repeat domain-containing ...741.3     37     31     49
238Q6P9J5    1016   KANK4_MOUSE KN motif and ankyrin repeat domai...491.3     37     33     59
239Q9J5G9    415   V034_FOWPN Putative ankyrin repeat protein FP...1871.4     36.6     21     43
240Q80YE7    1442   DAPK1_MOUSE Death-associated protein kinase 1...1021.4     37     25     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IMP:UniProtKB.
241Q8UVC3    1106   INVS_CHICK Inversin OS=Gallus gallus (Chicken...2141.5     37     24     34GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
records
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