Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181O15084    1053   ANR28_HUMAN Serine/threonine-protein phosphat...1760.35     38.9     24     40GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
182Q9UU77    207   YQMA_SCHPO Ankyrin repeat-containing protein ...560.36     37.7     34     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
183Q62422    215   OSTF1_MOUSE Osteoclast-stimulating factor 1 O...650.37     37.7     29     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IDA:MGI.
184Q6JAN1    1081   INVS_CANFA Inversin OS=Canis familiaris (Dog)...1507.8     34.7     21     37GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
185Q566C8    299   ANR54_RAT Ankyrin repeat domain-containing pr...580.38     38.1     43     59GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0045648; P:positive regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0010627; P:regulation of intracellular protein kinase cascade; ISS:UniProtKB.
186Q505D1    1053   ANR28_MOUSE Serine/threonine-protein phosphat...1760.38     38.9     24     40GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
187Q9NYT0    353   PLEK2_HUMAN Pleckstrin-2 OS=Homo sapiens (Hum...1230.39     38.5     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
188Q91WK7    299   ANR54_MOUSE Ankyrin repeat domain-containing ...580.4     38.1     43     59GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030496; C:midbody; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0032403; F:protein complex binding; IPI:MGI.::GO:0019887; F:protein kinase regulator activity; IDA:MGI.
GO:0007049; P:cell cycle; IDA:MGI.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0010627; P:regulation of intracellular protein kinase cascade; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IDA:MGI.
189Q9Y6X6    1858   MYO16_HUMAN Unconventional myosin-XVI OS=Homo...1580.42     38.9     26     44GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; IDA:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC.
GO:0051015; F:actin filament binding; ISS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0021549; P:cerebellum development; ISS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:HGNC.
190Q9UI32    602   GLSL_HUMAN Glutaminase liver isoform, mitocho...650.44     38.5     29     55GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0004359; F:glutaminase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.::GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0006541; P:glutamine metabolic process; IEA:InterPro.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
191Q55GV3    477   PAKC_DICDI Serine/threonine-protein kinase pa...1150.44     38.5     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0031273; P:negative regulation of pseudopodium assembly; IMP:dictyBase.
192Q8MJ50    214   OSTF1_BOVIN Osteoclast-stimulating factor 1 O...850.45     37.4     26     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
193Q6RI86    1125   TRPA1_RAT Transient receptor potential cation...1200.45     38.5     28     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
194A2A2Z9    1011   AN18B_HUMAN Ankyrin repeat domain-containing ...1590.45     38.5     28     46
195Q9Z2X3    231   PSD10_RAT 26S proteasome non-ATPase regulator...490.46     37.7     39     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
196Q1RGM2    168   Y1411_RICBR Putative ankyrin repeat protein R...820.47     37     30     56
197Q5DU14    1919   MYO16_MOUSE Unconventional myosin-XVI OS=Mus ...1550.48     38.5     27     45GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; ISS:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC.
GO:0051015; F:actin filament binding; ISS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0021549; P:cerebellum development; ISS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:HGNC.
198Q03017    500   CACT_DROME NF-kappa-B inhibitor cactus OS=Dro...1490.48     38.1     24     42GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.
GO:0008134; F:transcription factor binding; TAS:FlyBase.
GO:0019732; P:antifungal humoral response; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0009950; P:dorsal/ventral axis specification; IMP:FlyBase.::GO:0030097; P:hemopoiesis; TAS:FlyBase.::GO:0045087; P:innate immune response; NAS:FlyBase.::GO:0007399; P:nervous system development; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0006967; P:positive regulation of antifungal peptide biosynthetic process; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0008063; P:Toll signaling pathway; TAS:FlyBase.
199Q8ZWC4    256   Y1861_PYRAE Putative ankyrin repeat protein P...1610.49     37.7     29     43
200Q7ZYG4    214   OSTF1_XENLA Osteoclast-stimulating factor 1 O...720.51     37.4     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
201A5A3E0    1075   POTEF_HUMAN POTE ankyrin domain family member...1520.51     38.5     26     41GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.
202Q5U312    978   RAI14_RAT Ankycorbin OS=Rattus norvegicus (Ra...1500.51     38.5     24     38GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
203Q6XJU9    214   OSTF1_MONAL Osteoclast-stimulating factor 1 O...640.51     37.4     30     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
204Q7Z020    1296   TRPA1_DROME Transient receptor potential cati...540.51     38.5     37     56GO:0016021; C:integral to membrane; IC:UniProtKB.
GO:0005261; F:cation channel activity; IDA:UniProtKB.
GO:0034605; P:cellular response to heat; IDA:FlyBase.::GO:0042745; P:circadian sleep/wake cycle; IMP:FlyBase.::GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IMP:FlyBase.::GO:0007613; P:memory; IMP:FlyBase.::GO:0043052; P:thermotaxis; IDA:FlyBase.
205Q9BGT9    318   ASB7_MACFA Ankyrin repeat and SOCS box protei...1680.51     37.7     22     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
206Q5I148    168   IKBG2_MDBVW I-Kappa-B like protein G2 OS=Micr...500.53     37     40     58
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
207Q9H9B1    1298   EHMT1_HUMAN Histone-lysine N-methyltransferas...1010.57     38.5     32     47GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046976; F:histone methyltransferase activity (H3-K27 specific); ISS:UniProtKB.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.
208P42773    168   CDN2C_HUMAN Cyclin-dependent kinase 4 inhibit...510.57     36.6     33     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
209Q9SCX5    880   AKT5_ARATH Probable potassium channel AKT5 OS...2220.6     38.1     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
210A0JNU3    564   LPP60_MOUSE 60 kDa lysophospholipase OS=Mus m...470.6     38.1     40     64
GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:EC.::GO:0004067; F:asparaginase activity; IEA:EC.::GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
211Q9Z2F6    448   BCL3_MOUSE B-cell lymphoma 3 protein homolog ...1970.61     37.7     23     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0019730; P:antimicrobial humoral response; IMP:MGI.::GO:0042742; P:defense response to bacterium; IMP:MGI.::GO:0042832; P:defense response to protozoan; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0002268; P:follicular dendritic cell differentiation; IMP:MGI.::GO:0002467; P:germinal center formation; IMP:MGI.::GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0002315; P:marginal zone B cell differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IMP:MGI.::GO:0032729; P:positive regulation of interferon-gamma production; IMP:MGI.::GO:0045082; P:positive regulation of interleukin-10 biosynthetic process; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0048536; P:spleen development; IMP:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI.::GO:0045064; P:T-helper 2 cell differentiation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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