Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q9H672    318   ASB7_HUMAN Ankyrin repeat and SOCS box protei...1680.13     39.7     23     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
152P54644    444   KRAC_DICDI RAC family serine/threonine-protei...640.13     40     39     59GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase.
153Q9J4Z6    668   V244_FOWPN Putative ankyrin repeat protein FP...1590.14     40     26     45
154Q5RCK5    318   ASB7_PONAB Ankyrin repeat and SOCS box protei...1680.14     39.7     23     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
155A8FCG8    406   MTNW_BACP2 2,3-diketo-5-methylthiopentyl-1-ph...2590.17     39.7     23     39GO:0009536; C:plastid; IEA:InterPro.
GO:0043715; F:2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0016984; F:ribulose-bisphosphate carboxylase activity; IEA:InterPro.
GO:0015977; P:carbon fixation; IEA:InterPro.::GO:0019509; P:L-methionine salvage from methylthioadenosine; IEA:InterPro.
156Q1RJM6    97   Y357_RICBR Putative ankyrin repeat protein RB...840.18     37     35     49
157Q8TDY4    903   ASAP3_HUMAN Arf-GAP with SH3 domain, ANK repe...1080.18     40     31     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
158O88202    564   LPP60_RAT 60 kDa lysophospholipase OS=Rattus ...470.19     39.7     43     64GO:0005625; C:soluble fraction; IDA:RGD.
GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IMP:RGD.::GO:0004067; F:asparaginase activity; IDA:UniProtKB.::GO:0004622; F:lysophospholipase activity; IDA:UniProtKB.
GO:0006528; P:asparagine metabolic process; IDA:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006644; P:phospholipid metabolic process; IDA:UniProtKB.
159Q8C4V1    747   RHG24_MOUSE Rho GTPase-activating protein 24 ...1060.19     39.7     29     47GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
160Q5ZIJ9    954   MIB2_CHICK E3 ubiquitin-protein ligase MIB2 O...2240.19     39.7     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
161Q6AWW5    524   Y5262_ARATH Ankyrin repeat-containing protein...600.2     39.7     27     58GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
162Q8N2N9    1353   AN36B_HUMAN Ankyrin repeat domain-containing ...1580.2     39.7     27     44
163Q66JD7    286   ACBD6_XENTR Acyl-CoA-binding domain-containin...590.21     38.9     36     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
164O75832    226   PSD10_HUMAN 26S proteasome non-ATPase regulat...1586     34.3     22     45GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
165P59672    1150   ANS1A_MOUSE Ankyrin repeat and SAM domain-con...1512.5     36.2     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:UniProtKB.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0016322; P:neuron remodeling; IMP:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB.
166Q80T11    461   USH1G_MOUSE Usher syndrome type-1G protein ho...780.23     39.3     31     54GO:0015629; C:actin cytoskeleton; IDA:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IPI:MGI.
GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060113; P:inner ear receptor cell differentiation; IMP:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI.
167Q9J517    461   V218_FOWPN Putative ankyrin repeat protein FP...2070.24     39.3     25     46
168Q54GC8    288   ACBD6_DICDI Acyl-CoA-binding domain-containin...490.24     38.9     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
169Q495M9    461   USH1G_HUMAN Usher syndrome type-1G protein OS...780.25     39.3     31     54GO:0015629; C:actin cytoskeleton; ISS:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050957; P:equilibrioception; IMP:HGNC.::GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.::GO:0007605; P:sensory perception of sound; IMP:HGNC.
170Q9Z2X2    231   PSD10_MOUSE 26S proteasome non-ATPase regulat...490.26     38.5     41     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
171Q86HL8    362   OSB5_DICDI Oxysterol-binding protein 5 OS=Dic...1240.27     38.9     26     46
172Q9SAR5    342   AKR2_ARATH Ankyrin repeat domain-containing p...670.27     38.9     33     55GO:0031359; C:integral to chloroplast outer membrane; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0009816; P:defense response to bacterium, incompatible interaction; IMP:TAIR.::GO:0006457; P:protein folding; IDA:TAIR.::GO:0045036; P:protein targeting to chloroplast; IDA:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
173Q923M0    524   PP16A_MOUSE Protein phosphatase 1 regulatory ...1490.27     39.3     26     42GO:0005829; C:cytosol; TAS:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
174Q8MJ49    214   OSTF1_PIG Osteoclast-stimulating factor 1 OS=...650.29     38.1     29     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
175Q9WV52    353   PLEK2_MOUSE Pleckstrin-2 OS=Mus musculus (Mou...1230.31     38.5     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
176Q6DRG7    1049   MYPT1_DANRE Protein phosphatase 1 regulatory ...1470.33     38.9     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB.
GO:0051017; P:actin filament bundle assembly; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.
177Q91ZU0    318   ASB7_MOUSE Ankyrin repeat and SOCS box protei...1610.34     38.5     23     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
178Q9Y283    1065   INVS_HUMAN Inversin OS=Homo sapiens (Human). ...1506.3     35     21     37GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
179Q9SM23    338   ACBP1_ARATH Acyl-CoA-binding domain-containin...522.1     35.8     37     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0000062; F:fatty-acyl-CoA binding; IDA:TAIR.::GO:0032791; F:lead ion binding; IDA:TAIR.::GO:0070300; F:phosphatidic acid binding; IDA:TAIR.
GO:0006629; P:lipid metabolic process; IMP:TAIR.::GO:0006869; P:lipid transport; TAS:TAIR.::GO:0009409; P:response to cold; IMP:TAIR.::GO:0010288; P:response to lead ion; IEP:UniProtKB.
180Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...650.35     37.7     29     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
181O15084    1053   ANR28_HUMAN Serine/threonine-protein phosphat...1760.35     38.9     24     40GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
records
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