Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL019C
Length:
1283
Number of sequences:
5887
Description:
YDL019C OSH2 SGDID:S000002177, Chr IV from 421514-417663, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121A6NEL2    793   SWAHB_HUMAN Ankyrin repeat domain-containing ...950.027     42.4     27     44
122Q05823    741   RN5A_HUMAN 2-5A-dependent ribonuclease OS=Hom...1580.028     42.4     26     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IDA:UniProtKB.
GO:0051607; P:defense response to virus; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
123Q96T49    567   PP16B_HUMAN Protein phosphatase 1 regulatory ...1480.028     42.4     24     43GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0019903; F:protein phosphatase binding; NAS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
124P83757    489   CACT_DROYA NF-kappa-B inhibitor cactus OS=Dro...1490.028     42.4     25     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0046843; P:dorsal appendage formation; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
125Q80TI1    1356   PKHH1_MOUSE Pleckstrin homology domain-contai...950.029     42.7     31     49GO:0005856; C:cytoskeleton; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.
126Q12955    4377   ANK3_HUMAN Ankyrin-3 OS=Homo sapiens (Human)....1610.029     42.7     25     40GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045184; P:establishment of protein localization; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
127Q9ST43    145   PH1_ARATH Pleckstrin homology domain-containi...1280.03     40     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
128Q8IVE3    1493   PKHH2_HUMAN Pleckstrin homology domain-contai...1170.033     42.4     27     44GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005543; F:phospholipid binding; IEA:InterPro.
129Q9STP8    354   ACBP2_ARATH Acyl-CoA-binding domain-containin...510.034     41.6     37     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0009514; C:glyoxysome; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0000062; F:fatty-acyl-CoA binding; IDA:UniProtKB.::GO:0032791; F:lead ion binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006869; P:lipid transport; TAS:TAIR.::GO:0010288; P:response to lead ion; IEP:UniProtKB.
130Q5UQV3    765   YL371_MIMIV Putative ankyrin repeat protein L...850.035     42     34     52
131Q9BZL4    782   PP12C_HUMAN Protein phosphatase 1 regulatory ...1470.036     42     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
132Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...1596.7     34.7     26     43GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
133Q01484    3957   ANK2_HUMAN Ankyrin-2 OS=Homo sapiens (Human)....1471.7     37     26     43GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.
134Q571F8    602   GLSL_MOUSE Glutaminase liver isoform, mitocho...810.041     42     31     51GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004359; F:glutaminase activity; IEA:EC.
GO:0006541; P:glutamine metabolic process; IEA:InterPro.
135Q8N264    748   RHG24_HUMAN Rho GTPase-activating protein 24 ...1060.041     42     31     49GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
136Q92625    1134   ANS1A_HUMAN Ankyrin repeat and SAM domain-con...1740.043     42     23     45GO:0005737; C:cytoplasm; IDA:HPA.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0016322; P:neuron remodeling; ISS:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; ISS:UniProtKB.
137Q96NW4    1050   ANR27_HUMAN Ankyrin repeat domain-containing ...1610.045     42     25     43GO:0005769; C:early endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:LIFEdb.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0045022; P:early endosome to late endosome transport; IDA:MGI.
138Q3UMT1    782   PP12C_MOUSE Protein phosphatase 1 regulatory ...1550.048     41.6     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
139Q54HW1    232   PSD10_DICDI 26S proteasome non-ATPase regulat...1770.05     40.4     24     44
140Q876L5    763   AKR1_SACBA Palmitoyltransferase AKR1 OS=Sacch...1450.052     41.6     24     43GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
141Q6GNY1    1011   MIB1_XENLA E3 ubiquitin-protein ligase mib1 O...1620.052     41.6     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
142Q00IB7    1433   PKHH1_DANRE Pleckstrin homology domain-contai...1110.054     41.6     31     48GO:0005856; C:cytoskeleton; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001569; P:patterning of blood vessels; IMP:ZFIN.
143Q8N9V6    530   ANR53_HUMAN Ankyrin repeat domain-containing ...850.058     41.2     31     48
144Q5U2Z7    748   RHG24_RAT Rho GTPase-activating protein 24 OS...1090.066     41.2     31     48GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
145Q5ZJJ9    202   OSTF1_CHICK Osteoclast-stimulating factor 1 O...650.067     40     32     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
146Q60772    168   CDN2C_MOUSE Cyclin-dependent kinase 4 inhibit...610.07     39.3     31     49
GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.
147Q804S5    1030   MIB1_DANRE E3 ubiquitin-protein ligase mib1 O...1610.082     41.2     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
148A6QL64    1941   AN36A_HUMAN Ankyrin repeat domain-containing ...1550.085     41.2     26     45
149Q5REW9    1050   ANR27_PONAB Ankyrin repeat domain-containing ...1600.1     40.8     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
150Q9ULJ7    1429   ANR50_HUMAN Ankyrin repeat domain-containing ...1540.93     37.7     23     44
151Q9H672    318   ASB7_HUMAN Ankyrin repeat and SOCS box protei...1680.13     39.7     23     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
records
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