Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL017W
Length:
507
Number of sequences:
5887
Description:
YDL017W CDC7 SGDID:S000002175, Chr IV from 424209-425732, Genome Release 64-1-1, Verified ORF, "DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P19784    350   CSK22_HUMAN Casein kinase II subunit alpha' O...640.000003     53.1     34     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
122P54665    345   CC2H2_TRYBB Cell division control protein 2 h...1650.000003     53.1     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
123O60307    1309   MAST3_HUMAN Microtubule-associated serine/thr...1610.000003     53.9     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
124Q14AX6    1484   CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus...1630.000003     53.5     31     47GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:HGNC.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
125Q8BZN4    639   NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS...1960.000004     53.1     21     45
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
126Q5VN19    570   MPK11_ORYSJ Mitogen-activated protein kinase ...1810.000004     53.1     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
127Q54Y26    530   NDRA_DICDI Probable serine/threonine-protein ...2260.000004     52.8     27     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
128Q54PB4    481   MYLKE_DICDI Probable myosin light chain kinas...1620.000004     52.8     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
129Q61XD3    302   AIR2_CAEBR Aurora/IPL1-related protein kinase...1690.000005     52     29     44GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
130P08181    336   CSK2A_DROME Casein kinase II subunit alpha OS...640.000006     52     33     58GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005956; C:protein kinase CK2 complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0045475; P:locomotor rhythm; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0045880; P:positive regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IDA:FlyBase.
131O76484    353   CSK2A_SPOFR Casein kinase II subunit alpha OS...640.000006     52     33     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
132O94737    370   MAPK1_PNECA Mitogen-activated protein kinase ...1720.000006     52     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043008; F:ATP-dependent protein binding; IPI:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0016043; P:cellular component organization; IMP:UniProtKB.::GO:0040010; P:positive regulation of growth rate; IMP:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
133P84199    981   NEKL4_CAEEL Serine/threonine-protein kinase D...1890.000006     52.8     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
134Q9LM33    589   MPK8_ARATH Mitogen-activated protein kinase 8...1850.000007     52.4     26     43GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IPI:TAIR.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0042542; P:response to hydrogen peroxide; IEP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.
135Q8SRK8    322   KAPC_ENCCU Probable cAMP-dependent protein ki...1750.000007     51.6     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC.
136O54748    491   STK3_RAT Serine/threonine-protein kinase 3 OS...1920.000008     52     27     41GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
137Q95LJ0    313   PIM1_FELCA Serine/threonine-protein kinase pi...1610.000008     51.6     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
138P26794    313   PIM1_RAT Serine/threonine-protein kinase pim-...1610.000008     51.2     27     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
139Q54E34    352   Y6398_DICDI Probable protein kinase DDB_G0291...1660.000008     51.6     29     48GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; ISS:dictyBase.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
140Q54P26    593   SAMKB_DICDI Probable serine/threonine-protein...1670.000009     52     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
141P74297    574   SPKB_SYNY3 Serine/threonine-protein kinase B ...590.000009     52     41     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
142Q6TGC6    507   CBK1_PNECA Serine/threonine-protein kinase CB...3340.000009     52     26     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
143Q6L5F7    582   MPK17_ORYSJ Mitogen-activated protein kinase ...1810.000009     52     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
144Q641Z4    372   CDK9_RAT Cyclin-dependent kinase 9 OS=Rattus ...1920.000009     51.6     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
145Q99J95    372   CDK9_MOUSE Cyclin-dependent kinase 9 OS=Mus m...1920.000009     51.6     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0008024; C:positive transcription elongation factor complex b; TAS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.::GO:0017069; F:snRNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
146P20427    350   CSK22_BOVIN Casein kinase II subunit alpha' O...640.00001     51.2     33     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
147O54833    350   CSK22_MOUSE Casein kinase II subunit alpha' O...640.00001     51.2     33     56GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
148P21869    350   CSK22_CHICK Casein kinase II subunit alpha' O...640.00001     51.2     33     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
149P18334    360   CSK2A_CAEEL Casein kinase II subunit alpha OS...690.00001     50.8     32     55GO:0030424; C:axon; IDA:UniProtKB.::GO:0005929; C:cilium; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0034606; P:response to hermaphrodite contact; IMP:WormBase.::GO:0034608; P:vulval location; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
150P43068    501   MKC1_CANAX Mitogen-activated protein kinase M...590.00001     51.2     42     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
151Q96SB4    655   SRPK1_HUMAN SRSF protein kinase 1 OS=Homo sap...1550.00001     52     28     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0045087; P:innate immune response; IC:BHF-UCL.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.::GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; TAS:UniProtKB.::GO:0008380; P:RNA splicing; TAS:ProtInc.::GO:0035092; P:sperm chromatin condensation; TAS:UniProtKB.
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