Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL015C
Length:
310
Number of sequences:
5887
Description:
YDL015C TSC13 SGDID:S000002173, Chr IV from 426934-426002, Genome Release 64-1-1, reverse complement, Verified ORF, "Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q99190    310   TSC13_YEAST Enoyl reductase TSC13 OS=Saccharo...3100     636     100     100GO:0005789; C:endoplasmic reticulum membrane; IGI:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.::GO:0000038; P:very long-chain fatty acid metabolic process; IMP:SGD.
2Q55C17    300   TECR_DICDI Trans-2,3-enoyl-CoA reductase OS=D...2981e-45     162     35     54GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB.
3O94511    295   YN67_SCHPO Putative enoyl reductase C646.07c ...3171e-41     151     35     54GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; ISS:PomBase.
GO:0016631; F:enoyl-[acyl-carrier-protein reductase activity; NAS:PomBase.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; NAS:PomBase.::GO:0000038; P:very long-chain fatty acid metabolic process; ISS:PomBase.]
4Q3ZCD7    308   TECR_BOVIN Trans-2,3-enoyl-CoA reductase OS=B...2617e-29     117     33     49GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB.
5Q64232    308   TECR_RAT Trans-2,3-enoyl-CoA reductase OS=Rat...2617e-29     117     33     50GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB.
6Q9CY27    308   TECR_MOUSE Trans-2,3-enoyl-CoA reductase OS=M...2611e-28     116     33     50GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB.
7Q9NZ01    308   TECR_HUMAN Trans-2,3-enoyl-CoA reductase OS=H...2615e-28     114     32     49GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; IDA:UniProtKB.::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.::GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
8Q5HYJ1    363   TECRL_HUMAN Trans-2,3-enoyl-CoA reductase-lik...2552e-23     102     32     47GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
9Q8BFZ1    361   TECRL_MOUSE Trans-2,3-enoyl-CoA reductase-lik...2572e-19     90.5     31     46GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
10Q3SZ89    363   TECRL_BOVIN Trans-2,3-enoyl-CoA reductase-lik...3084e-18     87     28     46GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
11A8X8R3    309   PORED_CAEBR Probable polyprenol reductase OS=...2330.002     42.7     27     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
12P31214    254   S5A2_RAT 3-oxo-5-alpha-steroid 4-dehydrogenas...1080.26     36.2     29     40GO:0070852; C:cell body fiber; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IDA:RGD.::GO:0033218; F:amide binding; IPI:RGD.
GO:0006702; P:androgen biosynthetic process; IDA:RGD.::GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0060348; P:bone development; IEP:RGD.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IEP:RGD.::GO:0030540; P:female genitalia development; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0021854; P:hypothalamus development; IEP:RGD.::GO:0030539; P:male genitalia development; IEP:RGD.::GO:0008584; P:male gonad development; IEP:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032354; P:response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0006706; P:steroid catabolic process; IDA:RGD.
13P24008    259   S5A1_RAT 3-oxo-5-alpha-steroid 4-dehydrogenas...850.29     35.8     29     40GO:0070852; C:cell body fiber; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043209; C:myelin sheath; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0033218; F:amide binding; IDA:RGD.::GO:0070402; F:NADPH binding; IDA:RGD.
GO:0006702; P:androgen biosynthetic process; IDA:RGD.::GO:0060348; P:bone development; IEP:RGD.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0071549; P:cellular response to dexamethasone stimulus; IEP:RGD.::GO:0071872; P:cellular response to epinephrine stimulus; IEP:RGD.::GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0009267; P:cellular response to starvation; IEP:RGD.::GO:0071394; P:cellular response to testosterone stimulus; IEP:RGD.::GO:0021987; P:cerebral cortex development; IEP:RGD.::GO:0042747; P:circadian sleep/wake cycle, REM sleep; IEP:RGD.::GO:0016101; P:diterpenoid metabolic process; IEP:RGD.::GO:0030540; P:female genitalia development; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0021854; P:hypothalamus development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0030539; P:male genitalia development; IEP:RGD.::GO:0008584; P:male gonad development; IEP:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0042448; P:progesterone metabolic process; IDA:RGD.::GO:0042493; P:response to drug; IMP:RGD.::GO:0032354; P:response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0014850; P:response to muscle activity; IEP:RGD.::GO:0042428; P:serotonin metabolic process; IEP:RGD.::GO:0021510; P:spinal cord development; IEP:RGD.::GO:0021794; P:thalamus development; IEP:RGD.::GO:0001655; P:urogenital system development; IEP:RGD.
14Q757L1    738   TREB_ASHGO Probable trehalase OS=Y-1056) (Yea...980.37     36.2     28     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0004555; F:alpha,alpha-trehalase activity; IEA:EC.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0005993; P:trehalose catabolic process; IEA:InterPro.
15Q17428    309   PORED_CAEEL Probable polyprenol reductase OS=...1940.45     35.4     25     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
16Q28892    254   S5A2_MACFA 3-oxo-5-alpha-steroid 4-dehydrogen...1450.76     34.7     27     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0008202; P:steroid metabolic process; IEA:InterPro.
17Q99N99    254   S5A2_MOUSE 3-oxo-5-alpha-steroid 4-dehydrogen...850.9     34.3     28     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IMP:MGI.
GO:0006702; P:androgen biosynthetic process; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030539; P:male genitalia development; IMP:MGI.
18P31213    254   S5A2_HUMAN 3-oxo-5-alpha-steroid 4-dehydrogen...1081.2     33.9     27     40GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IEA:EC.::GO:0009917; F:sterol 5-alpha reductase activity; IDA:UniProtKB.
GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007267; P:cell-cell signaling; TAS:UniProtKB.::GO:0008584; P:male gonad development; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
19A5PJS2    257   S5A1_BOVIN 3-oxo-5-alpha-steroid 4-dehydrogen...842.4     33.1     26     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
20Q68FF9    255   S5A1_MOUSE 3-oxo-5-alpha-steroid 4-dehydrogen...853.6     32.7     27     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.
GO:0006702; P:androgen biosynthetic process; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
21O18765    254   S5A2_PIG 3-oxo-5-alpha-steroid 4-dehydrogenas...1515.2     32     25     39GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
22Q12802    2813   AKP13_HUMAN A-kinase anchor protein 13 OS=Hom...795.5     32.7     27     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004691; F:cAMP-dependent protein kinase activity; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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