Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL013W
Length:
619
Number of sequences:
5887
Description:
YDL013W SLX5 SGDID:S000002171, Chr IV from 429067-430926, Genome Release 64-1-1, Verified ORF, "Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32828    619   SLX5_YEAST E3 ubiquitin-protein ligase comple...6190     1275     100     100GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:SGD.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0032183; F:SUMO binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:SGD.::GO:0016567; P:protein ubiquitination; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000723; P:telomere maintenance; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q8R079    450   BFAR_MOUSE Bifunctional apoptosis regulator O...550.012     42     35     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
3Q5PQN2    450   BFAR_RAT Bifunctional apoptosis regulator OS=...550.013     42     35     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
4Q9NZS9    450   BFAR_HUMAN Bifunctional apoptosis regulator O...550.043     40.4     33     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005198; F:structural molecule activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
5Q12933    501   TRAF2_HUMAN TNF receptor-associated factor 2 ...871.1     35.8     30     49GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.
GO:0005174; F:CD40 receptor binding; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; NAS:ProtInc.::GO:0046625; F:sphingolipid binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0043623; P:cellular protein complex assembly; ISS:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070207; P:protein homotrimerization; IPI:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
6P46865    955   KINL_LEICH Kinesin-like protein K39 OS=Leishm...804.5     34.3     30     56GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
7Q5SSE9    5034   ABCAD_MOUSE ATP-binding cassette sub-family A...1064.9     34.3     23     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0006810; P:transport; IEA:UniProtKB-KW.
8A8J2Z9    396   FEN1_CHLRE Flap endonuclease 1 OS=Chlamydomon...617.4     33.1     34     52GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
records
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