Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL008W
Length:
165
Number of sequences:
5887
Description:
YDL008W APC11 SGDID:S000002166, Chr IV from 433497-433994, Genome Release 64-1-1, Verified ORF, "Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; contains a RING-H2 domain that is required for activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9R049    643   AMFR_MOUSE E3 ubiquitin-protein ligase AMFR O...910.005     40     29     41GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
32Q04781    1562   LTN1_YEAST E3 ubiquitin-protein ligase lister...620.006     39.7     27     44GO:0005634; C:nucleus; IDA:SGD.
GO:0043022; F:ribosome binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
33Q9LY41    334   ATL4_ARATH E3 ubiquitin-protein ligase ATL4 O...990.008     39.3     38     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
34Q9SG96    181   ATL72_ARATH RING-H2 finger protein ATL72 OS=A...620.008     38.9     37     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
35Q9P0P0    153   RN181_HUMAN E3 ubiquitin-protein ligase RNF18...970.009     38.5     26     39
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
36Q65XX2    1446   LTN1_CAEEL E3 ubiquitin-protein ligase lister...300.01     39.3     37     70
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q9UKV5    643   AMFR2_HUMAN E3 ubiquitin-protein ligase AMFR ...910.01     39.3     27     41GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
38Q9CY62    165   RN181_MOUSE E3 ubiquitin-protein ligase RNF18...860.02     37.4     29     40
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
39P38239    180   YBR2_YEAST Uncharacterized RING finger protei...590.026     37.4     37     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
40Q9M0R4    357   ATL37_ARATH Putative RING-H2 finger protein A...720.029     37.7     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
41O43085    695   DSC1_SCHPO DSC E3 ubiquitin ligase complex su...270.03     37.7     41     70GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
42Q9NVW2    624   RNF12_HUMAN E3 ubiquitin-protein ligase RLIM ...640.033     37.7     30     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; NAS:UniProtKB.
GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
43Q9WTV7    600   RNF12_MOUSE E3 ubiquitin-protein ligase RLIM ...640.037     37.4     30     42GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
44Q9VE61    147   RN181_DROME E3 ubiquitin-protein ligase RNF18...730.037     36.6     32     51
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
45Q4WZJ6    418   RAD18_ASPFU Postreplication repair E3 ubiquit...660.039     37.4     38     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
46Q641J8    622   RF12A_XENLA E3 ubiquitin-protein ligase RNF12...640.042     37.4     30     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000578; P:embryonic axis specification; IMP:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
47Q07G42    639   RNF12_XENTR E3 ubiquitin-protein ligase RNF12...640.045     37.4     30     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
48Q7T037    757   RF12B_XENLA E3 ubiquitin-protein ligase RNF12...640.049     37     30     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
49Q8LFY8    413   ATL54_ARATH RING-H2 finger protein ATL54 OS=A...850.054     37     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
50Q99MP8    591   BRAP_MOUSE BRCA1-associated protein OS=Mus mu...320.055     37     44     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
51Q6AXU4    165   RN181_RAT E3 ubiquitin-protein ligase RNF181 ...480.06     36.2     40     50
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
52Q9DBU5    667   RNF6_MOUSE E3 ubiquitin-protein ligase RNF6 O...570.062     37     33     44GO:0030424; C:axon; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IDA:MGI.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030517; P:negative regulation of axon extension; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IMP:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
53Q7Z569    592   BRAP_HUMAN BRCA1-associated protein OS=Homo s...320.066     36.6     44     63GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI.
GO:0008139; F:nuclear localization sequence binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.
54Q7TMV1    668   RN139_MOUSE E3 ubiquitin-protein ligase RNF13...720.071     36.6     28     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031396; P:regulation of protein ubiquitination; ISS:UniProtKB.
55Q9VW09    1747   LTN1_DROME E3 ubiquitin-protein ligase lister...260.074     36.6     50     65
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
56Q9FGJ6    166   ATL79_ARATH RING-H2 finger protein ATL79 OS=A...340.075     35.8     44     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
57Q5Z5F2    251   ATL61_ORYSJ E3 ubiquitin-protein ligase Os06g...750.079     36.2     32     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
58Q9ZT49    200   ATL45_ARATH RING-H2 finger protein ATL45 OS=A...670.08     36.2     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
59O22755    185   ATL44_ARATH RING-H2 finger protein ATL44 OS=A...340.087     35.8     44     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
60Q5RBT7    664   RN139_PONAB E3 ubiquitin-protein ligase RNF13...720.098     36.2     28     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
61Q8WU17    664   RN139_HUMAN E3 ubiquitin-protein ligase RNF13...720.098     36.2     28     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0070613; P:regulation of protein processing; IDA:UniProtKB.::GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
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