Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL007W
Length:
437
Number of sequences:
5887
Description:
YDL007W RPT2 SGDID:S000002165, Chr IV from 438047-439360, Genome Release 64-1-1, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O74894    389   PRS6B_SCHPO 26S protease regulatory subunit 6...3651e-117     356     49     71GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
32P33298    428   PRS6B_YEAST 26S protease regulatory subunit 6...3765e-117     355     48     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
33Q9V287    396   PAN_PYRAB Proteasome-activating nucleotidase ...3436e-117     354     49     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0022623; C:proteasome-activating nucleotidase complex; IEA:HAMAP.
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0016887; F:ATPase activity; IEA:HAMAP.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0010498; P:proteasomal protein catabolic process; IEA:HAMAP.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0043335; P:protein unfolding; IEA:HAMAP.
34C5A6P8    397   PAN_THEGJ Proteasome-activating nucleotidase ...3401e-116     353     50     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
35Q8U4H3    396   PAN_PYRFU Proteasome-activating nucleotidase ...3431e-116     353     49     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
36O57940    399   PAN_PYRHO Proteasome-activating nucleotidase ...3432e-116     353     49     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
37Q5JHS5    397   PAN_PYRKO Proteasome-activating nucleotidase ...3402e-115     350     49     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
38B6YXR2    398   PAN_THEON Proteasome-activating nucleotidase ...3406e-115     349     49     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
39P78578    423   PRS6B_ASPNG 26S protease regulatory subunit 6...3549e-115     350     48     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
40A6VHR1    407   PAN_METM7 Proteasome-activating nucleotidase ...3434e-114     347     49     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
41A9A916    407   PAN_METM6 Proteasome-activating nucleotidase ...3431e-113     346     49     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
42Q6LWR0    407   PAN_METMP Proteasome-activating nucleotidase ...3432e-113     346     49     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
43Q0W257    417   PAN_UNCMA Proteasome-activating nucleotidase ...3546e-113     345     47     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
44A6UQT3    407   PAN_METVS Proteasome-activating nucleotidase ...3538e-113     344     48     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
45A4G0S4    407   PAN_METM5 Proteasome-activating nucleotidase ...3431e-112     343     48     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
46B8GGN4    412   PAN_METPE Proteasome-activating nucleotidase ...3383e-112     343     47     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
47Q8SQK0    453   PRS8_ENCCU 26S protease regulatory subunit 8 ...3665e-112     343     48     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
48O18413    405   PRS8_DROME 26S protease regulatory subunit 8 ...3274e-111     340     49     72GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0004175; F:endopeptidase activity; IDA:FlyBase.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
49Q2FQ56    412   PAN_METHJ Proteasome-activating nucleotidase ...3356e-111     339     50     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
50Q94BQ2    419   PRS8B_ARATH 26S protease regulatory subunit 8...3289e-111     339     51     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
51Q9C5U3    419   PRS8A_ARATH 26S protease regulatory subunit 8...3281e-110     338     50     71GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
52Q8PY58    420   PAN_METMA Proteasome-activating nucleotidase ...3521e-110     338     45     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
53Q01939    405   PRS8_YEAST 26S protease regulatory subunit 8 ...3265e-110     337     50     71GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0019904; F:protein domain specific binding; IDA:SGD.
GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0006289; P:nucleotide-excision repair; IGI:SGD.::GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IPI:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.
54P54814    402   PRS8_MANSE 26S protease regulatory subunit 8 ...3056e-110     337     52     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
55P62198    406   PRS8_RAT 26S protease regulatory subunit 8 OS...3276e-110     337     49     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
56P62197    406   PRS8_PIG 26S protease regulatory subunit 8 OS...3276e-110     337     49     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
57P62196    406   PRS8_MOUSE 26S protease regulatory subunit 8 ...3276e-110     337     49     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
58P62195    406   PRS8_HUMAN 26S protease regulatory subunit 8 ...3276e-110     337     49     70GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:UniProtKB.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043069; P:negative regulation of programmed cell death; NAS:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0016032; P:viral reproduction; TAS:Reactome.
59P62194    406   PRS8_BOVIN 26S protease regulatory subunit 8 ...3276e-110     337     49     70GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
60Q25544    414   PRS8_NAEFO 26S protease regulatory subunit 8 ...3067e-110     337     53     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
61Q8TI88    421   PAN_METAC Proteasome-activating nucleotidase ...3521e-109     336     45     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
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