Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL006W
Length:
281
Number of sequences:
5887
Description:
YDL006W PTC1 SGDID:S000002164, Chr IV from 439909-440754, Genome Release 64-1-1, Verified ORF, "Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P35182    281   PP2C1_YEAST Protein phosphatase 2C homolog 1 ...2810     583     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IMP:SGD.
2P40371    347   PP2C1_SCHPO Protein phosphatase 2C homolog 1 ...2644e-74     236     45     66GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
3Q8RXV3    311   P2C59_ARATH Probable protein phosphatase 2C 5...2623e-40     147     36     54GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0044419; P:interspecies interaction between organisms; IPI:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:TAIR.
4Q8LAY8    354   P2C69_ARATH Probable protein phosphatase 2C 6...3018e-40     147     33     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
5Q4PSE8    447   P2C71_ARATH Probable protein phosphatase 2C 7...3041e-39     148     34     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
6Q67UX7    348   P2C10_ORYSJ Probable protein phosphatase 2C 1...2553e-39     145     35     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
7Q9LNW3    442   P2C03_ARATH Protein phosphatase 2C 3 OS=Arabi...2452e-37     142     34     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
8Q7XR06    282   P2C45_ORYSJ Probable protein phosphatase 2C 4...2842e-37     139     34     50GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
9Q5Z6F5    327   P2C59_ORYSJ Probable protein phosphatase 2C 5...2552e-37     140     35     55GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
10O62829    382   PPM1A_BOVIN Protein phosphatase 1A OS=Bos tau...2707e-37     139     34     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
11P49443    382   PPM1A_MOUSE Protein phosphatase 1A OS=Mus mus...2701e-36     139     34     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
GO:0006470; P:protein dephosphorylation; IDA:MGI.
12P35813    382   PPM1A_HUMAN Protein phosphatase 1A OS=Homo sa...2701e-36     139     34     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IDA:BHF-UCL.
13P20650    382   PPM1A_RAT Protein phosphatase 1A OS=Rattus no...2702e-36     139     34     51GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
14P35814    382   PPM1A_RABIT Protein phosphatase 1A OS=Oryctol...2702e-36     139     34     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
15O75688    479   PPM1B_HUMAN Protein phosphatase 1B OS=Homo sa...2794e-36     139     33     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.
16O62830    484   PPM1B_BOVIN Protein phosphatase 1B OS=Bos tau...2795e-36     139     32     48GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
17Q6L5C4    491   P2C52_ORYSJ Probable protein phosphatase 2C 5...2568e-36     138     33     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
18P36993    390   PPM1B_MOUSE Protein phosphatase 1B OS=Mus mus...2742e-35     135     33     48GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
19Q8VZN9    371   P2C11_ARATH Probable protein phosphatase 2C 1...2614e-35     135     35     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
20P35815    390   PPM1B_RAT Protein phosphatase 1B OS=Rattus no...2799e-35     134     32     47GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
21Q94AT1    420   P2C76_ARATH Probable protein phosphatase 2C 7...2561e-34     134     34     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
22Q0JL75    377   P2C07_ORYSJ Probable protein phosphatase 2C 7...2347e-34     131     34     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
23Q0J2L7    358   P2C68_ORYSJ Probable protein phosphatase 2C 6...2759e-34     130     31     49GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
24Q0JAA0    321   P2C44_ORYSJ Probable protein phosphatase 2C 4...2541e-32     127     32     50
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
25P49597    434   P2C56_ARATH Protein phosphatase 2C 56 OS=Arab...2681e-32     129     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IGI:UniProtKB.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009409; P:response to cold; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.
26Q9LNP9    511   P2C07_ARATH Protein phosphatase 2C 7 OS=Arabi...2692e-32     128     31     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.
27Q09173    414   PP2C3_SCHPO Protein phosphatase 2C homolog 3 ...2332e-32     127     36     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
28O04719    423   P2C77_ARATH Protein phosphatase 2C 77 OS=Arab...2763e-32     127     30     47GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IGI:TAIR.::GO:0010205; P:photoinhibition; IMP:TAIR.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0006970; P:response to osmotic stress; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.
29Q5SN75    403   P2C08_ORYSJ Probable protein phosphatase 2C 8...2673e-32     127     30     50GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
30Q80TL0    749   PPM1E_MOUSE Protein phosphatase 1E OS=Mus mus...2904e-32     129     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
31Q80Z30    750   PPM1E_RAT Protein phosphatase 1E OS=Rattus no...2905e-32     129     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
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