Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL006W
Length:
281
Number of sequences:
5887
Description:
YDL006W PTC1 SGDID:S000002164, Chr IV from 439909-440754, Genome Release 64-1-1, Verified ORF, "Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q80Z30    750   PPM1E_RAT Protein phosphatase 1E OS=Rattus no...2905e-32     129     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
32A0DTY1    301   PP2C4_PARTE Probable protein phosphatase 2C 4...2875e-32     125     31     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
33Q9ZW21    362   P2C24_ARATH Probable protein phosphatase 2C 2...2776e-32     125     32     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
34Q6ING9    373   PPM1K_XENLA Protein phosphatase 1K, mitochond...2429e-32     125     34     55GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
35Q8WY54    764   PPM1E_HUMAN Protein phosphatase 1E OS=Homo sa...2901e-31     128     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
36A5PJZ2    360   PPM1L_BOVIN Protein phosphatase 1L OS=Bos tau...2631e-31     125     34     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
37A0BQL0    300   PP2C3_PARTE Probable protein phosphatase 2C 3...2902e-31     123     31     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
38P49593    454   PPM1F_HUMAN Protein phosphatase 1F OS=Homo sa...2673e-31     125     32     49GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:UniProtKB.::GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0044387; P:negative regulation of protein kinase activity by regulation of protein phosphorylation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0050921; P:positive regulation of chemotaxis; IMP:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.::GO:0045927; P:positive regulation of growth; IMP:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
39P49598    399   P2C37_ARATH Protein phosphatase 2C 37 OS=Arab...2314e-31     124     33     55GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IMP:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0010360; P:negative regulation of anion channel activity; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.
40Q8N3J5    372   PPM1K_HUMAN Protein phosphatase 1K, mitochond...2414e-31     124     34     54GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
41Q9SLA1    392   P2C22_ARATH Probable protein phosphatase 2C 2...2784e-31     124     31     47GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0050688; P:regulation of defense response to virus; IMP:TAIR.
42Q5SGD2    360   PPM1L_HUMAN Protein phosphatase 1L OS=Homo sa...2635e-31     123     33     53GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
43Q8BHN0    360   PPM1L_MOUSE Protein phosphatase 1L OS=Mus mus...2635e-31     123     33     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:MGI.
GO:0000165; P:MAPK cascade; IPI:MGI.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IDA:MGI.
44Q84JI0    404   P2C30_ORYSJ Probable protein phosphatase 2C 3...2317e-31     123     34     50GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
45O15743    975   SPNA_DICDI Protein spalten OS=Dictyostelium d...2787e-31     126     32     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.::GO:0001726; C:ruffle; IDA:dictyBase.
GO:0005525; F:GTP binding; IMP:dictyBase.::GO:0000287; F:magnesium ion binding; IDA:dictyBase.::GO:0030145; F:manganese ion binding; IDA:dictyBase.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:dictyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.::GO:0030154; P:cell differentiation; IMP:dictyBase.::GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0006470; P:protein dephosphorylation; IDA:dictyBase.
46Q2PC20    372   PPM1K_BOVIN Protein phosphatase 1K, mitochond...2417e-31     123     34     53GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
47Q8BXN7    372   PPM1K_MOUSE Protein phosphatase 1K, mitochond...2411e-30     122     34     53GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
48Q652Z7    378   P2C55_ORYSJ Probable protein phosphatase 2C 5...2351e-30     122     33     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
49Q9CAJ0    511   P2C16_ARATH Protein phosphatase 2C 16 OS=Arab...2792e-30     123     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.
50Q6L4R7    445   P2C53_ORYSJ Probable protein phosphatase 2C 5...2713e-30     122     29     48GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
51A0BLX0    300   PP2C2_PARTE Probable protein phosphatase 2C 2...2873e-30     120     29     48GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
52Q5N9N2    414   P2C09_ORYSJ Probable protein phosphatase 2C 9...2283e-30     121     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
53Q6L5H6    387   P2C50_ORYSJ Probable protein phosphatase 2C 5...2754e-30     121     31     48GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
54Q9FIF5    413   P2C78_ARATH Probable protein phosphatase 2C 7...2275e-30     121     33     50GO:0033106; C:cis-Golgi network membrane; IDA:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IGI:TAIR.
GO:0009658; P:chloroplast organization; IMP:TAIR.::GO:0010150; P:leaf senescence; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0010118; P:stomatal movement; IMP:TAIR.
55Q7XU84    352   P2C42_ORYSJ Probable protein phosphatase 2C 4...2885e-30     120     28     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
56Q8L7I4    283   P2C17_ARATH Probable protein phosphatase 2C 1...2615e-30     119     32     49GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
57Q8N819    430   PPM1N_HUMAN Probable protein phosphatase 1N O...2896e-30     120     30     46
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
58P93006    380   P2C27_ARATH Probable protein phosphatase 2C 2...2829e-30     120     31     48GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
59Q65XK7    381   P2C51_ORYSJ Probable protein phosphatase 2C 5...2911e-29     119     31     49GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
60Q9FLI3    416   P2C75_ARATH Probable protein phosphatase 2C 7...2951e-29     120     31     46GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.
61Q09172    370   PP2C2_SCHPO Protein phosphatase 2C homolog 2 ...2361e-29     119     34     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
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