Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL003W
Length:
566
Number of sequences:
5887
Description:
YDL003W MCD1 SGDID:S000002161, Chr IV from 444683-446383, Genome Release 64-1-1, Verified ORF, "Essential subunit of the cohesin complex required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12158    566   SCC1_YEAST Sister chromatid cohesion protein ...5660     1156     100     100GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0034990; C:nuclear mitotic cohesin complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0034087; P:establishment of mitotic sister chromatid cohesion; IMP:SGD.::GO:0007076; P:mitotic chromosome condensation; IMP:SGD.::GO:0006473; P:protein acetylation; IDA:UniProtKB.
2P30776    628   RAD21_SCHPO Cohesin subunit rad21 OS=Schizosa...1290.0000000002     67.4     30     53GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000794; C:condensed nuclear chromosome; IC:PomBase.::GO:0030892; C:mitotic cohesin complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:PomBase.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:PomBase.
3D2HSB3    554   RD21L_AILME Double-strand-break repair protei...920.000000002     63.5     36     55GO:0030893; C:meiotic cohesin complex; ISS:UniProtKB.::GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007128; P:meiotic prophase I; ISS:UniProtKB.
4A2AU37    552   RD21L_MOUSE Double-strand-break repair protei...920.000000007     62     35     54GO:0030893; C:meiotic cohesin complex; IDA:UniProtKB.::GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007128; P:meiotic prophase I; IEP:UniProtKB.
5O93310    629   RAD21_XENLA Double-strand-break repair protei...910.000000008     62     34     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
6O60216    631   RAD21_HUMAN Double-strand-break repair protei...910.000000009     62     33     54GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0008278; C:cohesin complex; TAS:BHF-UCL.::GO:0000228; C:nuclear chromosome; IEA:InterPro.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; TAS:ProtInc.::GO:0007091; P:mitotic metaphase/anaphase transition; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0071168; P:protein localization to chromatin; IMP:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
7Q3SWX9    630   RAD21_BOVIN Double-strand-break repair protei...910.000000009     62     33     54GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
8Q61550    635   RAD21_MOUSE Double-strand-break repair protei...910.000000009     62     33     54GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000228; C:nuclear chromosome; IEA:InterPro.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
9Q9H4I0    556   RD21L_HUMAN Double-strand-break repair protei...910.00000001     61.2     35     54GO:0030893; C:meiotic cohesin complex; ISS:UniProtKB.::GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007128; P:meiotic prophase I; ISS:UniProtKB.
10Q9FQ20    810   SCC12_ARATH Sister chromatid cohesion 1 prote...880.00002     51.2     32     48GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IMP:TAIR.::GO:0007067; P:mitosis; IEP:TAIR.
11Q9S7T7    627   SCC11_ARATH Sister chromatid cohesion 1 prote...940.002     44.7     30     49GO:0000228; C:nuclear chromosome; IEA:InterPro.
GO:0051455; P:attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation; IMP:TAIR.::GO:0006325; P:chromatin organization; IMP:TAIR.::GO:0010032; P:meiotic chromosome condensation; IMP:TAIR.::GO:0051754; P:meiotic sister chromatid cohesion, centromeric; IMP:TAIR.
12Q9FQ19    693   SCC13_ARATH Sister chromatid cohesion 1 prote...430.077     39.7     37     60GO:0000228; C:nuclear chromosome; IEA:InterPro.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0009561; P:megagametogenesis; IMP:TAIR.::GO:0007067; P:mitosis; IEP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.
13O95072    547   REC8_HUMAN Meiotic recombination protein REC8...920.12     38.9     26     50
GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.::GO:0007062; P:sister chromatid cohesion; TAS:ProtInc.
14P36626    561   REC8_SCHPO Meiotic recombination protein rec8...830.25     37.7     28     48GO:0000939; C:condensed chromosome inner kinetochore; IDA:PomBase.::GO:0030893; C:meiotic cohesin complex; IDA:PomBase.::GO:0000228; C:nuclear chromosome; IC:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051455; P:attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation; IMP:PomBase.::GO:0030999; P:linear element assembly; IMP:PomBase.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:PomBase.::GO:0045144; P:meiotic sister chromatid segregation; IDA:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
15Q9JKY5    1068   HIP1R_MOUSE Huntingtin-interacting protein 1-...923.9     34.3     25     47GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IDA:MGI.::GO:0005856; C:cytoskeleton; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0006898; P:receptor-mediated endocytosis; ISS:UniProtKB.
16O75146    1068   HIP1R_HUMAN Huntingtin-interacting protein 1-...546.1     33.5     31     59GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
17Q18040    422   OAT_CAEEL Probable ornithine aminotransferase...1218.6     32.7     25     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004587; F:ornithine-oxo-acid transaminase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
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