Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL002C
Length:
203
Number of sequences:
5887
Description:
YDL002C NHP10 SGDID:S000002160, Chr IV from 447578-446967, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein related to mammalian high mobility group proteins; preferentially binds DNA ends, protecting them from exonucleatic cleavage; likely component of the chromatin-remodeling complex INO80 complex; proposed to be involved in DNA repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P36402    384   TCF7_HUMAN Transcription factor 7 OS=Homo sap...1070.43     34.7     32     52GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0007420; P:brain development; IBA:RefGenome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0071353; P:cellular response to interleukin-4; IDA:UniProtKB.::GO:0048699; P:generation of neurons; IBA:RefGenome.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
122B1H349    777   SOX6_XENTR Transcription factor Sox-6 OS=Xeno...500.51     34.7     28     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
123Q6P8W9    181   HMGB4_MOUSE High mobility group protein B4 OS...720.53     33.9     25     50GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
124Q99PM1    619   TOX4_RAT TOX high mobility group box family m...720.54     34.7     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
125Q8BU11    619   TOX4_MOUSE TOX high mobility group box family...720.54     34.7     26     53GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
126A4IIJ8    436   SOX10_XENTR Transcription factor Sox-10 OS=Xe...970.56     34.3     25     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0032183; F:SUMO binding; ISS:UniProtKB.
GO:0030318; P:melanocyte differentiation; ISS:UniProtKB.::GO:0014029; P:neural crest formation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
127Q9W757    461   SOX10_CHICK Transcription factor SOX-10 OS=Ga...950.58     34.3     23     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0060959; P:cardiac neuron development; IEP:UniProtKB.
128Q8AXQ4    244   SOX12_XENLA Transcription factor Sox-12 OS=Xe...510.6     33.9     27     59GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
129Q5R6A9    621   TOX4_PONAB TOX high mobility group box family...720.66     34.3     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
130O94842    621   TOX4_HUMAN TOX high mobility group box family...720.66     34.3     26     53GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0072357; C:PTW/PP1 phosphatase complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
131Q05738    395   SRY_MOUSE Sex-determining region Y protein OS...510.7     34.3     27     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008584; P:male gonad development; IDA:MGI.::GO:0030238; P:male sex determination; IGI:MGI.::GO:0010629; P:negative regulation of gene expression; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
132Q0P5K4    619   TOX4_BOVIN TOX high mobility group box family...720.73     34.3     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
133A4QNP0    597   TOX4_XENTR TOX high mobility group box family...830.79     34.3     24     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
134Q6DJL0    597   TOX4A_XENLA TOX high mobility group box famil...830.8     33.9     24     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
135P36631    468   STE11_SCHPO Transcription factor ste11 OS=Sch...590.84     33.9     27     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0034064; C:Tor2-Mei2-Ste11 complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.
GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0051039; P:positive regulation of transcription during meiosis; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
136Q96NM4    488   TOX2_HUMAN TOX high mobility group box family...520.86     33.9     35     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
137Q6IRR0    594   TOX4B_XENLA TOX high mobility group box famil...830.88     33.9     24     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
138A8WWH5    439   POP1_CAEBR Protein pop-1 OS=Caenorhabditis br...630.9     33.9     24     62GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0008356; P:asymmetric cell division; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
139Q28EW4    566   SOX13_XENTR Transcription factor Sox-13 OS=Xe...661.1     33.5     29     56GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
140P40639    72   AES4_ALLMI SRY-related protein AES4 OS=Alliga...491.1     31.2     24     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
141Q9Z1J1    584   TF7L1_MOUSE Transcription factor 7-like 1 OS=...841.2     33.5     26     55GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome.
GO:0008595; P:anterior/posterior axis specification, embryo; IMP:MGI.::GO:0048319; P:axial mesoderm morphogenesis; IMP:MGI.::GO:0007420; P:brain development; IBA:RefGenome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0048699; P:generation of neurons; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0046022; P:positive regulation of transcription from RNA polymerase II promoter during mitosis; IDA:MGI.::GO:2000036; P:regulation of stem cell maintenance; IMP:MGI.::GO:0043588; P:skin development; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
142P40649    567   SOX13_XENLA Transcription factor Sox-13 OS=Xe...691.2     33.5     29     55GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
143Q00417    419   TCF7_MOUSE Transcription factor 7 OS=Mus musc...1071.2     33.5     31     53GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome.
GO:0046632; P:alpha-beta T cell differentiation; IGI:MGI.::GO:0007420; P:brain development; IBA:RefGenome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0048557; P:embryonic digestive tract morphogenesis; IGI:MGI.::GO:0030538; P:embryonic genitalia morphogenesis; IGI:MGI.::GO:0048619; P:embryonic hindgut morphogenesis; IGI:MGI.::GO:0048699; P:generation of neurons; IBA:RefGenome.::GO:0021915; P:neural tube development; IGI:MGI.::GO:0042981; P:regulation of apoptotic process; IDA:MGI.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0033153; P:T cell receptor V(D)J recombination; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
144Q90ZH7    361   SX18B_XENLA Transcription factor Sox-18B OS=X...571.2     33.5     30     63GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0007507; P:heart development; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
145Q03257    240   SRY_SHEEP Sex-determining region Y protein OS...731.2     33.1     25     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
146Q9BG90    204   SRY_MACMU Sex-determining region Y protein OS...641.3     32.7     30     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
147Q90ZH8    363   SX18A_XENLA Transcription factor Sox-18A OS=X...571.4     33.1     30     63GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
148B3DLD3    362   SOX18_XENTR Transcription factor Sox-18 OS=Xe...571.4     33.1     30     65GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0007507; P:heart development; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
149Q06831    440   SOX4_MOUSE Transcription factor SOX-4 OS=Mus ...1101.4     33.1     24     50GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.
GO:0035910; P:ascending aorta morphogenesis; IMP:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IMP:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0021782; P:glial cell development; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060993; P:kidney morphogenesis; IMP:BHF-UCL.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0002328; P:pro-B cell differentiation; IMP:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL.
150Q9LGR0    641   SSP1A_ORYSJ FACT complex subunit SSRP1-A OS=O...831.4     33.1     19     48GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
151Q6TC39    218   SRY_MIRAN Sex-determining region Y protein OS...1041.6     32.7     23     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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