rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q02779 | 954 | M3K10_HUMAN Mitogen-activated protein kinase ... | 60 | 0.0001 | 48.9 | 42 | 55 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB. | 92 | Q1E878 | 612 | HSE1_COCIM Class E vacuolar protein-sorting m... | 50 | 0.0001 | 48.5 | 46 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 93 | Q6BNP6 | 512 | HSE1_DEBHA Class E vacuolar protein-sorting m... | 51 | 0.0001 | 48.1 | 47 | 61 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 94 | Q0U6X7 | 618 | HSE1_PHANO Class E vacuolar protein-sorting m... | 77 | 0.0002 | 48.1 | 39 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 95 | Q07750 | 212 | ADF1_CAEEL Actin-depolymerizing factor 1, iso... | 68 | 0.0002 | 46.6 | 32 | 56 | GO:0005865; C:striated muscle thin filament; IDA:WormBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:WormBase. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:WormBase.::GO:0051014; P:actin filament severing; IDA:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:WormBase.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:WormBase. | 96 | O74749 | 373 | HSE1_SCHPO Class E vacuolar protein-sorting m... | 50 | 0.0002 | 47.8 | 44 | 60 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 97 | O94875 | 1100 | SRBS2_HUMAN Sorbin and SH3 domain-containing ... | 50 | 0.033 | 41.2 | 38 | 54 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 98 | O70145 | 525 | NCF2_MOUSE Neutrophil cytosol factor 2 OS=Mus... | 65 | 0.0002 | 48.1 | 37 | 58 | GO:0001669; C:acrosomal vesicle; IDA:MGI. | | | | | | | | | | GO:0048365; F:Rac GTPase binding; IPI:MGI. | | | | | | | | | | GO:0042554; P:superoxide anion generation; IDA:MGI. | 99 | Q8AXV0 | 367 | SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C... | 82 | 0.0002 | 47.8 | 32 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 100 | Q3UTJ2 | 1180 | SRBS2_MOUSE Sorbin and SH3 domain-containing ... | 50 | 0.056 | 40.4 | 36 | 54 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 101 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 111 | 0.0002 | 48.1 | 32 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 102 | O35413 | 1196 | SRBS2_RAT Sorbin and SH3 domain-containing pr... | 50 | 0.063 | 40 | 36 | 54 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 103 | O43150 | 1006 | ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe... | 99 | 0.0002 | 48.1 | 36 | 49 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 104 | Q0CJU8 | 597 | HSE1_ASPTN Class E vacuolar protein-sorting m... | 50 | 0.0002 | 47.8 | 44 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 105 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 75 | 0.62 | 37 | 29 | 45 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 106 | Q91X43 | 789 | SH319_MOUSE SH3 domain-containing protein 19 ... | 56 | 0.05 | 40.4 | 29 | 57 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 107 | Q8N157 | 1196 | AHI1_HUMAN Jouberin OS=Homo sapiens (Human). ... | 68 | 0.0002 | 48.1 | 41 | 56 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB. | 108 | Q7S6J4 | 745 | HSE1_NEUCR Class E vacuolar protein-sorting m... | 69 | 0.0002 | 47.8 | 41 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 109 | A7E3N2 | 527 | NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu... | 63 | 0.0002 | 47.8 | 38 | 57 | GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD. | 110 | O75791 | 330 | GRAP2_HUMAN GRB2-related adapter protein 2 OS... | 54 | 0.0003 | 47 | 41 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 111 | Q5A895 | 498 | HSE1_CANAL Class E vacuolar protein-sorting m... | 51 | 0.0003 | 47.4 | 47 | 59 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 112 | P34092 | 1111 | MYOB_DICDI Myosin IB heavy chain OS=Dictyoste... | 75 | 0.0003 | 47.4 | 40 | 52 | GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0032031; F:myosin I head/neck binding; IDA:dictyBase. | | | | | | | | | | GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051707; P:response to other organism; TAS:dictyBase. | 113 | P38753 | 452 | HSE1_YEAST Class E vacuolar protein-sorting m... | 51 | 0.0004 | 47 | 45 | 59 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD. | 114 | B0BNA1 | 340 | SH3Y1_RAT SH3 domain-containing YSC84-like pr... | 56 | 0.0004 | 46.6 | 39 | 57 | | | | | | | | | | | | | | | | | | | | | | 115 | Q66L42 | 940 | M3K10_MOUSE Mitogen-activated protein kinase ... | 60 | 0.0004 | 47.4 | 40 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 116 | Q09822 | 927 | CDC15_SCHPO Cell division control protein 15 ... | 55 | 0.0004 | 47 | 36 | 58 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032178; C:medial membrane band; IDA:PomBase. | | | | | | | | | | GO:0043495; F:protein anchor; TAS:PomBase. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0061166; P:establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051125; P:regulation of actin nucleation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 117 | O08641 | 340 | SH3Y1_MOUSE SH3 domain-containing YSC84-like ... | 56 | 0.0004 | 46.2 | 39 | 57 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 118 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 53 | 0.0005 | 46.6 | 38 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 119 | P34258 | 493 | YKA7_CAEEL Uncharacterized protein B0303.7 OS... | 58 | 4.9 | 33.9 | 34 | 50 | | | | | | | | | | | | | | | | | | | | | | 120 | Q9R1Z8 | 733 | VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ... | 51 | 0.031 | 40.8 | 33 | 53 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:MGI. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI. | 121 | Q99M51 | 377 | NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu... | 53 | 0.0006 | 46.2 | 38 | 60 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. |