rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | A0JNJ1 | 403 | STAC_BOVIN SH3 and cysteine-rich domain-conta... | 60 | 4.1 | 33.9 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 392 | Q5DU57 | 656 | SPT13_MOUSE Spermatogenesis-associated protei... | 54 | 4.2 | 33.9 | 35 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 393 | Q9D0K1 | 405 | PEX13_MOUSE Peroxisomal membrane protein PEX1... | 59 | 4.2 | 33.9 | 34 | 53 | | | | | | | | | | | GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI. | 394 | Q6TGW5 | 214 | OSTF1_DANRE Osteoclast-stimulating factor 1 O... | 51 | 4.2 | 33.5 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 395 | Q03526 | 625 | ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=... | 96 | 4.2 | 33.9 | 28 | 50 | GO:0005829; C:cytosol; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IMP:MGI.::GO:0032633; P:interleukin-4 production; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001865; P:NK T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB. | 396 | A9CB74 | 466 | EM55_PAPAN 55 kDa erythrocyte membrane protei... | 66 | 4.4 | 33.9 | 33 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB. | 397 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 53 | 4.4 | 33.9 | 34 | 51 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 398 | Q9HCF6 | 1732 | TRPM3_HUMAN Transient receptor potential cati... | 114 | 4.6 | 34.3 | 24 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 399 | Q00013 | 466 | EM55_HUMAN 55 kDa erythrocyte membrane protei... | 66 | 4.6 | 33.9 | 33 | 44 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 400 | Q5RDW4 | 466 | EM55_PONAB 55 kDa erythrocyte membrane protei... | 66 | 4.8 | 33.9 | 33 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB. | 401 | A0PYX6 | 390 | DEOB_CLONN Phosphopentomutase OS=Clostridium ... | 87 | 4.9 | 33.5 | 33 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008973; F:phosphopentomutase activity; IEA:EC. | | | | | | | | | | GO:0043094; P:cellular metabolic compound salvage; IEA:InterPro.::GO:0009117; P:nucleotide metabolic process; IEA:InterPro. | 402 | O95180 | 2353 | CAC1H_HUMAN Voltage-dependent T-type calcium ... | 112 | 5.2 | 33.9 | 29 | 42 | GO:0005891; C:voltage-gated calcium channel complex; TAS:ProtInc. | | | | | | | | | | GO:0008332; F:low voltage-gated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.::GO:0035865; P:cellular response to potassium ion; IEP:UniProtKB.::GO:0034651; P:cortisol biosynthetic process; IMP:UniProtKB.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0007520; P:myoblast fusion; TAS:ProtInc.::GO:2000344; P:positive regulation of acrosome reaction; IMP:UniProtKB.::GO:0008016; P:regulation of heart contraction; TAS:ProtInc. | 403 | P0DJ27 | 137 | COFB_DICDI Cofilin-1B OS=Dictyostelium discoi... | 61 | 5.3 | 32.3 | 31 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 404 | P0DJ26 | 137 | COFA_DICDI Cofilin-1A OS=Dictyostelium discoi... | 61 | 5.3 | 32.3 | 31 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 405 | Q6XJU9 | 214 | OSTF1_MONAL Osteoclast-stimulating factor 1 O... | 51 | 5.4 | 33.1 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 406 | P16885 | 1265 | PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 52 | 5.7 | 33.9 | 38 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB. | 407 | Q6BWX4 | 143 | COFI_DEBHA Cofilin OS=0083 / IGC 2968) (Yeast... | 118 | 6 | 32.3 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 408 | Q337A5 | 151 | ADF10_ORYSJ Actin-depolymerizing factor 10 OS... | 90 | 6.1 | 32.3 | 29 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 409 | A6NNM3 | 1639 | RIM3B_HUMAN RIMS-binding protein 3B OS=Homo s... | 58 | 6.5 | 33.5 | 36 | 55 | | | | | | | | | | | | | | | | | | | | | | 410 | A6NJZ7 | 1639 | RIM3C_HUMAN RIMS-binding protein 3C OS=Homo s... | 58 | 6.7 | 33.5 | 36 | 55 | | | | | | | | | | | | | | | | | | | | | | 411 | Q5U4Y2 | 167 | COF2_XENTR Cofilin-2 OS=Xenopus tropicalis (W... | 57 | 6.8 | 32.3 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 412 | Q99469 | 402 | STAC_HUMAN SH3 and cysteine-rich domain-conta... | 66 | 7.2 | 33.1 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 413 | Q759P0 | 143 | COFI_ASHGO Cofilin OS=Y-1056) (Yeast) (Eremot... | 63 | 7.3 | 32 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 414 | Q91ZR2 | 614 | SNX18_MOUSE Sorting nexin-18 OS=Mus musculus ... | 54 | 7.3 | 33.1 | 30 | 54 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 415 | Q5XHH8 | 167 | COF2_XENLA Cofilin-2 OS=Xenopus laevis (Afric... | 53 | 7.6 | 32.3 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 416 | P0CR78 | 660 | HSE1_CRYNJ Class E vacuolar protein-sorting m... | 50 | 7.9 | 33.1 | 34 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 417 | Q6FV81 | 143 | COFI_CANGA Cofilin OS=NRRL Y-65) (Yeast) (Tor... | 118 | 8 | 32 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 418 | P0CR79 | 660 | HSE1_CRYNB Class E vacuolar protein-sorting m... | 50 | 8.1 | 33.1 | 34 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 419 | Q10902 | 472 | NHR2_CAEEL Nuclear hormone receptor family me... | 175 | 8.6 | 33.1 | 23 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 420 | Q9ZSK3 | 139 | ADF4_ARATH Actin-depolymerizing factor 4 OS=A... | 68 | 9 | 31.6 | 31 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009870; P:defense response signaling pathway, resistance gene-dependent; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR. | 421 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 130 | 9.1 | 33.1 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. |