Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR088W
Length:
592
Number of sequences:
5887
Description:
YCR088W ABP1 SGDID:S000000684, Chr III from 265068-266846, Genome Release 64-1-1, Verified ORF, "Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q9QY53    687   NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M...650.21     38.1     32     54GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB.
302Q7TSG5    549   SH321_MOUSE SH3 domain-containing protein 21 ...500.23     38.1     34     52
303P42680    631   TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo...530.23     38.1     36     55GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0010543; P:regulation of platelet activation; IDA:UniProtKB.
304P16277    499   BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus ...570.24     38.1     32     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
305Q05876    534   FYN_CHICK Tyrosine-protein kinase Fyn OS=Gall...510.24     38.1     35     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0015631; F:tubulin binding; ISS:AgBase.
GO:0030900; P:forebrain development; ISS:AgBase.::GO:0001764; P:neuron migration; ISS:AgBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:AgBase.::GO:0008360; P:regulation of cell shape; ISS:AgBase.
306Q99JB8    424   PACN3_MOUSE Protein kinase C and casein kinas...510.24     37.7     37     61GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.
307Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...500.27     38.1     34     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
308O95153    1857   RIMB1_HUMAN Peripheral-type benzodiazepine re...810.28     38.1     33     47GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0030156; F:benzodiazepine receptor binding; IPI:UniProtKB.
309Q04736    541   YES_MOUSE Tyrosine-protein kinase Yes OS=Mus ...510.28     37.7     35     49GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0015758; P:glucose transport; IDA:MGI.
310P42683    508   LCK_CHICK Proto-oncogene tyrosine-protein kin...680.28     37.7     28     50GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.
311Q14767    1821   LTBP2_HUMAN Latent-transforming growth factor...830.28     38.1     34     42GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005578; C:proteinaceous extracellular matrix; TAS:ProtInc.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
GO:0009306; P:protein secretion; TAS:ProtInc.::GO:0006605; P:protein targeting; TAS:ProtInc.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
312Q15052    776   ARHG6_HUMAN Rho guanine nucleotide exchange f...500.28     37.7     34     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
313Q8K4I3    771   ARHG6_MOUSE Rho guanine nucleotide exchange f...500.29     37.7     34     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
314Q3USJ8    740   FCSD2_MOUSE FCH and double SH3 domains protei...560.3     37.7     43     57
315O74653    871   POB1_SCHPO Protein pob1 OS=Schizosaccharomyce...580.34     37.7     33     55GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.
316Q28923    539   YES_CANFA Tyrosine-protein kinase Yes OS=Cani...520.39     37.4     35     48GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
317P97369    339   NCF4_MOUSE Neutrophil cytosol factor 4 OS=Mus...900.42     37     27     47GO:0005737; C:cytoplasm; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0007154; P:cell communication; IEA:InterPro.
318Q8BYZ1    367   ABI3_MOUSE ABI gene family member 3 OS=Mus mu...480.42     37     40     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
319O60861    476   GAS7_HUMAN Growth arrest-specific protein 7 O...400.42     37     43     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.
320P50545    524   HCK_RAT Tyrosine-protein kinase HCK OS=Rattus...600.44     37     32     52GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB.
321O14259    415   YFP2_SCHPO SH3 domain-containing protein C7D4...550.48     37     33     49GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:2000157; P:negative regulation of ubiquitin-specific protease activity; IMP:PomBase.
322Q9UUD0    501   YNQA_SCHPO Uncharacterized protein C19C2.10 O...2130.48     37     25     42GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
323A7E3N7    446   NOXA1_RAT NADPH oxidase activator 1 OS=Rattus...520.49     37     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016176; F:superoxide-generating NADPH oxidase activator activity; ISS:UniProtKB.
GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
324Q8MJ50    214   OSTF1_BOVIN Osteoclast-stimulating factor 1 O...410.5     36.2     44     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
325Q7T2V3    1005   M3K10_XENLA Mitogen-activated protein kinase ...630.6     37     37     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
GO:0071570; P:cement gland development; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB.
326Q60992    868   VAV2_MOUSE Guanine nucleotide exchange factor...800.6     37     35     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.
327P08631    526   HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo...570.65     36.6     32     53GO:0005901; C:caveola; IDA:UniProtKB.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031234; C:extrinsic to internal side of plasma membrane; IMP:UniProtKB.::GO:0005925; C:focal adhesion; IMP:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0002758; P:innate immune response-activating signal transduction; TAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; TAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043299; P:leukocyte degranulation; TAS:UniProtKB.::GO:0002522; P:leukocyte migration involved in immune response; TAS:UniProtKB.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:UniProtKB.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; TAS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0071801; P:regulation of podosome assembly; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045728; P:respiratory burst after phagocytosis; TAS:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
328Q13588    217   GRAP_HUMAN GRB2-related adapter protein OS=Ho...530.65     35.8     36     55GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
329Q95UN8    1161   M3KSL_DROME Mitogen-activated protein kinase ...580.69     36.6     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0071361; P:cellular response to ethanol; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048804; P:imaginal disc-derived female genitalia morphogenesis; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
330Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...410.7     35.8     44     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
331P08103    524   HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus ...600.7     36.6     32     52GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0050830; P:defense response to Gram-positive bacterium; IGI:MGI.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB.
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