Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR088W
Length:
592
Number of sequences:
5887
Description:
YCR088W ABP1 SGDID:S000000684, Chr III from 265068-266846, Genome Release 64-1-1, Verified ORF, "Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q8VCZ6    750   SGSM3_MOUSE Small G protein signaling modulat...520.043     40.4     40     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
242Q6P6U0    517   FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus...520.043     40.4     37     52GO:0005829; C:cytosol; IDA:RGD.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.
243Q6P6R7    749   SGSM3_RAT Small G protein signaling modulator...520.043     40.4     40     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
244P32790    1244   SLA1_YEAST Actin cytoskeleton-regulatory comp...560.044     40.4     32     50GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0006897; P:endocytosis; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.
245A6H8I2    753   SGSM3_XENLA Small G protein signaling modulat...540.046     40.4     39     61GO:0005622; C:intracellular; IEA:InterPro.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
246Q9Z0W5    441   PACN1_RAT Protein kinase C and casein kinase ...510.05     40     41     59
GO:0007010; P:cytoskeleton organization; IDA:RGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
247Q5R411    444   PACN1_PONAB Protein kinase C and casein kinas...510.05     40     41     59
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
248Q9BY11    444   PACN1_HUMAN Protein kinase C and casein kinas...510.052     40     41     59
GO:0004672; F:protein kinase activity; NAS:UniProtKB.
GO:0006897; P:endocytosis; NAS:UniProtKB.
249Q61644    441   PACN1_MOUSE Protein kinase C and casein kinas...510.052     40     41     59GO:0030137; C:COPI-coated vesicle; IDA:MGI.
GO:0008092; F:cytoskeletal protein binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI.
250P00527    528   YES_AVISY Tyrosine-protein kinase transformin...780.054     40     32     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
251Q14155    803   ARHG7_HUMAN Rho guanine nucleotide exchange f...500.06     40     36     56GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
252Q5R8P5    365   SHLB1_PONAB Endophilin-B1 OS=Pongo abelii (Su...580.063     39.7     38     50GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
253Q9Y371    365   SHLB1_HUMAN Endophilin-B1 OS=Homo sapiens (Hu...580.063     39.7     38     50GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IPI:HGNC.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IDA:HGNC.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
254Q6AYE2    365   SHLB1_RAT Endophilin-B1 OS=Rattus norvegicus ...580.068     39.7     38     50GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
255Q2KI13    747   SGSM3_BOVIN Small G protein signaling modulat...520.076     39.7     38     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
256P38822    633   BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere...780.078     39.7     40     51GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
257Q5ZIR1    366   SHLB1_CHICK Endophilin-B1 OS=Gallus gallus (C...590.081     39.3     37     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
258Q96HU1    749   SGSM3_HUMAN Small G protein signaling modulat...520.081     39.7     38     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB.
259Q6WKZ7    506   NOSTN_MOUSE Nostrin OS=Mus musculus (Mouse). ...520.085     39.3     35     54GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
260P32793    468   YSC84_YEAST Protein YSC84 OS=Saccharomyces ce...580.086     39.3     34     57GO:0030479; C:actin cortical patch; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD.
261Q8QFX1    1325   RIMB2_CHICK RIMS-binding protein 2 OS=Gallus ...590.088     39.7     41     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
262P39743    482   RV167_YEAST Reduced viability upon starvation...560.091     39.3     38     52GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD.
263O15034    1052   RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sa...590.092     39.7     41     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
264Q9H7D0    1870   DOCK5_HUMAN Dedicator of cytokinesis protein ...680.094     39.7     32     54GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
265Q08DN7    844   VAV_BOVIN Proto-oncogene vav OS=Bos taurus (B...540.098     39.3     44     57GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
266B2RY04    1868   DOCK5_MOUSE Dedicator of cytokinesis protein ...680.099     39.7     32     54GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
267P27446    537   FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph...520.1     39.3     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
268Q06449    215   PIN3_YEAST [PSI+] inducibility protein 3 OS=S...670.1     38.1     31     51GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IPI:SGD.
269O75044    1071   FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p...540.11     39.3     31     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
270A7TKW4    1202   SLA1_VANPO Actin cytoskeleton-regulatory comp...566.2     33.5     39     54GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
271P42687    497   SPK1_DUGTI Tyrosine-protein kinase SPK-1 OS=D...510.11     38.9     39     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
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