Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR084C
Length:
713
Number of sequences:
5887
Description:
YCR084C TUP1 SGDID:S000000680, Chr III from 262452-260311, Genome Release 64-1-1, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P16649    713   TUP1_YEAST General transcriptional corepresso...7130     1474     100     100GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
2P56094    682   TUP1_KLULA General transcriptional corepresso...7270     751     57     68
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3C4YFX2    511   TUP1_CANAW Transcriptional repressor TUP1 OS=...832e-19     95.5     59     75
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4P0CY34    512   TUP1_CANAL Transcriptional repressor TUP1 OS=...832e-19     95.5     59     75GO:0005625; C:soluble fraction; IDA:CGD.
GO:0016337; P:cell-cell adhesion; IMP:CGD.::GO:0071280; P:cellular response to copper ion; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0044409; P:entry into host; IMP:CGD.::GO:0051834; P:evasion or tolerance of defenses of other organism involved in symbiotic interaction; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0045827; P:negative regulation of isoprenoid metabolic process; IMP:CGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0009372; P:quorum sensing; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5P78706    604   RCO1_NEUCR Transcriptional repressor rco-1 OS...780.0001     49.3     38     54
GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q09715    614   TUP11_SCHPO Transcriptional repressor tup11 O...7273e-116     369     33     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IGI:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006342; P:chromatin silencing; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7O76734    579   TUP1_DICDI General transcriptional corepresso...1350.099     39.7     24     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q9UUG8    598   TUP12_SCHPO Transcriptional repressor tup12 O...1030.000000000003     73.6     38     62GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IDA:PomBase.
GO:0043156; P:chromatin remodeling in response to cation stress; IMP:PomBase.::GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...1930.0000000000008     75.9     25     48
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
10Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...2234e-22     105     32     49
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
11Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1590.00000006     60.1     31     38
12Q54KL5    335   WDR5_DICDI WD repeat-containing protein 5 hom...2283e-21     99.8     29     46GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
GO:0042393; F:histone binding; ISS:dictyBase.
GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
13Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...2272e-23     110     31     54
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
14P49695    742   PKWA_THECU Probable serine/threonine-protein ...1790.000000000000001     84.3     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
15Q498M4    334   WDR5_RAT WD repeat-containing protein 5 OS=Ra...2375e-17     86.7     27     43GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P61965    334   WDR5_MOUSE WD repeat-containing protein 5 OS=...2375e-17     86.7     27     43GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17P61964    334   WDR5_HUMAN WD repeat-containing protein 5 OS=...2375e-17     86.7     27     43GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q2KIG2    334   WDR5_BOVIN WD repeat-containing protein 5 OS=...2376e-17     86.3     27     43GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q9V3J8    361   WDS_DROME Protein will die slowly OS=Drosophi...2705e-31     129     30     53GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
20Q3Y8L7    446   WDR69_CHLRE Outer row dynein assembly protein...1627e-18     90.5     29     55GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
21Q5M786    334   WDR5_XENTR WD repeat-containing protein 5 OS=...2375e-17     86.3     27     43GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q4V8C4    328   WDR5B_RAT WD repeat-containing protein 5B OS=...2394e-18     90.1     28     44
23C3XVT5    406   LIS1_BRAFL Lissencephaly-1 homolog OS=Branchi...1850.0000000002     67     23     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
24Q9D7H2    328   WDR5B_MOUSE WD repeat-containing protein 5B O...2393e-18     90.5     29     43
25Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...620.78     36.2     32     50
26A7S338    409   LIS1_NEMVE Lissencephaly-1 homolog OS=Nematos...1910.0000000001     67.8     27     45GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
27Q5RE95    330   WDR5B_PONAB WD repeat-containing protein 5B O...620.71     36.6     32     50
28Q6P2Y2    415   WDR69_XENTR Outer row dynein assembly protein...2300.000000000000001     83.2     25     45GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
29A8X8C6    368   TG125_CAEBR WD repeat-containing protein tag-...2703e-23     105     28     47
30Q93847    395   YZLL_CAEEL Uncharacterized WD repeat-containi...3050.000000000009     71.2     26     42
31Q5FWQ6    415   WDR69_XENLA Outer row dynein assembly protein...2670.000000000000001     83.6     24     43GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
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