Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR084C
Length:
713
Number of sequences:
5887
Description:
YCR084C TUP1 SGDID:S000000680, Chr III from 262452-260311, Genome Release 64-1-1, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601O94244    430   HAT2_SCHPO Histone acetyltransferase type B s...2270.00000000009     68.2     26     48GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031511; C:Mis6-Sim4 complex; TAS:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0034080; P:CenH3-containing nucleosome assembly at centromere; TAS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016575; P:histone deacetylation; IMP:PomBase.::GO:0051382; P:kinetochore assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0031066; P:regulation of histone deacetylation at centromere; IMP:PomBase.
602B0XAF3    338   CIAO1_CULQU Probable cytosolic iron-sulfur pr...2430.000000002     63.5     26     44
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
603O14727    1248   APAF_HUMAN Apoptotic protease-activating fact...1710.001     45.8     24     44GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc.
604Q6CXX3    861   HIR1_KLULA Protein HIR1 OS=1267 / NRRL Y-1140...2570.00008     49.7     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
605O94365    494   UTP15_SCHPO U3 small nucleolar RNA-associated...1670.002     45.1     25     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0032040; C:small-subunit processome; ISS:PomBase.::GO:0005819; C:spindle; IDA:PomBase.::GO:0034455; C:t-UTP complex; ISS:PomBase.
GO:0030515; F:snoRNA binding; ISS:PomBase.
GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
606Q54S59    299   WDR61_DICDI WD repeat-containing protein 61 h...1700.00006     49.3     27     47
607O42937    796   COPB2_SCHPO Probable coatomer subunit beta' O...2620.002     45.1     19     41GO:0030126; C:COPI vesicle coat; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; ISS:PomBase.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISS:PomBase.
608Q9Z2K5    326   LST8_RAT Target of rapamycin complex subunit ...920.44     37     23     46GO:0005829; C:cytosol; IDA:RGD.
609Q4P8R5    814   MDV1_USTMA Mitochondrial division protein 1 O...920.27     38.1     30     42GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
610Q17QU5    326   LST8_BOVIN Target of rapamycin complex subuni...920.45     37     23     46GO:0005737; C:cytoplasm; ISS:UniProtKB.
611Q0CJD8    654   MDV1_ASPTN Mitochondrial division protein 1 O...1412.6     35     29     41GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
612B4MY77    335   CIAO1_DROWI Probable cytosolic iron-sulfur pr...1350.0003     47.4     28     44
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
613Q9D0N7    572   CAF1B_MOUSE Chromatin assembly factor 1 subun...1720.007     43.5     23     45GO:0033186; C:CAF-1 complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031497; P:chromatin assembly; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
614Q7QJ33    428   WDR12_ANOGA Ribosome biogenesis protein WDR12...790.49     37.4     34     51GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
615Q54WA3    316   PEX7_DICDI Peroxisomal targeting signal 2 rec...1930.0007     45.8     24     43GO:0005777; C:peroxisome; ISS:dictyBase.
GO:0005053; F:peroxisome matrix targeting signal-2 binding; ISS:dictyBase.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
616Q5SQM0    1958   EMAL6_MOUSE Echinoderm microtubule-associated...1089.2     33.5     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
617Q20059    683   WDR48_CAEEL WD repeat-containing protein 48 h...2470.0001     49.3     22     38
618Q8C0J2    607   A16L1_MOUSE Autophagy-related protein 16-1 OS...1210.0000000003     67.4     26     50GO:0000421; C:autophagic vacuole membrane; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0000045; P:autophagic vacuole assembly; TAS:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
619Q6DDF0    495   WDR37_XENLA WD repeat-containing protein 37 O...860.19     38.5     29     47
620Q17GR9    337   CIAO1_AEDAE Probable cytosolic iron-sulfur pr...1700.000000007     61.6     26     49
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
621O17468    1047   HIRA_DROME Protein HIRA homolog OS=Drosophila...2760.00000002     61.2     24     38GO:0001673; C:male germ cell nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.
GO:0006336; P:DNA replication-independent nucleosome assembly; IMP:FlyBase.::GO:0035042; P:fertilization, exchange of chromosomal proteins; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
622Q28DW0    333   CIAO1_XENTR Probable cytosolic iron-sulfur pr...3260.0000000002     66.6     25     40
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
623B4GDM7    335   CIAO1_DROPE Probable cytosolic iron-sulfur pr...1760.038     40.4     24     42
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
624Q91WM3    475   U3IP2_MOUSE U3 small nucleolar RNA-interactin...2860.005     43.9     22     42GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
625A8PTE4    674   MDV1_MALGO Mitochondrial division protein 1 O...2770.000004     53.9     22     39GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
626Q4V837    710   DTLA_XENLA Denticleless protein homolog A OS=...2150.026     41.6     23     40GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
627Q7Z4S6    1674   KI21A_HUMAN Kinesin-like protein KIF21A OS=Ho...1610.78     37     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
628Q8CFD5    397   ERCC8_MOUSE DNA excision repair protein ERCC-...2240.0007     46.2     26     42
GO:0009411; P:response to UV; IMP:MGI.::GO:0010165; P:response to X-ray; IMP:MGI.
629Q9BVC4    326   LST8_HUMAN Target of rapamycin complex subuni...920.75     36.6     23     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.
630O43818    475   U3IP2_HUMAN U3 small nucleolar RNA-interactin...2860.023     41.6     21     41GO:0030532; C:small nuclear ribonucleoprotein complex; TAS:ProtInc.::GO:0005732; C:small nucleolar ribonucleoprotein complex; TAS:ProtInc.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; TAS:ProtInc.
631A2AHJ4    1799   BRWD3_MOUSE Bromodomain and WD repeat-contain...860.38     38.1     22     50
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
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