Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR084C
Length:
713
Number of sequences:
5887
Description:
YCR084C TUP1 SGDID:S000000680, Chr III from 262452-260311, Genome Release 64-1-1, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571Q6GPU3    711   DTLB_XENLA Denticleless protein homolog B OS=...2120.41     37.7     23     40GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
572Q6P1W0    713   DTL_XENTR Denticleless protein homolog OS=Xen...2150.002     45.1     26     40GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
573Q8WWQ0    1821   PHIP_HUMAN PH-interacting protein OS=Homo sap...1790.034     41.2     21     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005158; F:insulin receptor binding; NAS:UniProtKB.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; NAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
574Q9UKT8    454   FBXW2_HUMAN F-box/WD repeat-containing protei...1480.056     40.4     28     42
GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
GO:0006508; P:proteolysis; TAS:ProtInc.
575Q6LA54    933   YF48_SCHPO Uncharacterized WD repeat-containi...3140.0003     47.8     21     36GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
576Q5RAC9    607   A16L1_PONAB Autophagy-related protein 16-1 OS...1360.0001     48.9     27     47GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
577Q5REE0    518   UTP15_PONAB U3 small nucleolar RNA-associated...2440.00000000005     69.3     25     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
578Q9DCJ1    326   LST8_MOUSE Target of rapamycin complex subuni...920.44     37     23     46
GO:0030838; P:positive regulation of actin filament polymerization; IMP:MGI.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.
579Q6P1V3    422   WSB1_XENTR WD repeat and SOCS box-containing ...1650.000002     54.7     24     43
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
580A4RJV3    661   MDV1_MAGO7 Mitochondrial division protein 1 O...1111.9     35.4     25     42GO:0030015; C:CCR4-NOT core complex; ISS:PAMGO_MGG.::GO:0005741; C:mitochondrial outer membrane; ISS:PAMGO_MGG.
GO:0051020; F:GTPase binding; ISS:PAMGO_MGG.
GO:0000266; P:mitochondrial fission; ISS:PAMGO_MGG.::GO:0000002; P:mitochondrial genome maintenance; ISS:PAMGO_MGG.::GO:0006402; P:mRNA catabolic process; ISS:PAMGO_MGG.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:PAMGO_MGG.::GO:0006354; P:transcription elongation, DNA-dependent; ISS:PAMGO_MGG.::GO:0006352; P:transcription initiation, DNA-dependent; ISS:PAMGO_MGG.
581Q922B6    594   TRAF7_MOUSE E3 ubiquitin-protein ligase TRAF7...810.22     38.5     27     51GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000185; P:activation of MAPKKK activity; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
582Q20636    356   GBB2_CAEEL Guanine nucleotide-binding protein...2320.0000002     57.4     25     39GO:0043025; C:neuronal cell body; IDA:WormBase.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007212; P:dopamine receptor signaling pathway; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IMP:WormBase.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IGI:WormBase.::GO:0040012; P:regulation of locomotion; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0032094; P:response to food; IMP:WormBase.
583Q54QU5    359   WDR89_DICDI WD repeat-containing protein 89 h...1670.00000000005     68.6     28     54
584Q6Q0C0    670   TRAF7_HUMAN E3 ubiquitin-protein ligase TRAF7...810.16     38.9     27     51GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IDA:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
585Q58D00    454   FBXW2_BOVIN F-box/WD repeat-containing protei...1480.067     40     28     42
586Q8MY12    780   MHCKC_DICDI Myosin heavy chain kinase C OS=Di...2400.0000000003     67     25     41GO:0005826; C:actomyosin contractile ring; IDA:dictyBase.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IMP:dictyBase.::GO:0045159; F:myosin II binding; ISS:dictyBase.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IMP:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.
587A0AUS0    487   WSDU1_DANRE WD repeat, SAM and U-box domain-c...3460.00000006     59.3     23     40GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
588Q7ZW33    517   UTP15_DANRE U3 small nucleolar RNA-associated...1330.24     38.1     24     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
589B5X9P2    330   CIO1A_SALSA Probable cytosolic iron-sulfur pr...1200.0006     46.2     31     49
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
590P36130    643   CAF4_YEAST CCR4-associated factor 4 OS=Saccha...2780.000000004     63.5     23     40GO:0030014; C:CCR4-NOT complex; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0000266; P:mitochondrial fission; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:SGD.
591Q5R1S9    566   CAF1B_CHICK Chromatin assembly factor 1 subun...1510.016     42.4     21     48GO:0033186; C:CAF-1 complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031497; P:chromatin assembly; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
592Q2UA71    436   HAT2_ASPOR Histone acetyltransferase type B s...2820.00000000007     68.6     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
593Q9H7D7    661   WDR26_HUMAN WD repeat-containing protein 26 O...2650.00005     50.4     25     38GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
594B4KTK4    331   CIAO1_DROMO Probable cytosolic iron-sulfur pr...1320.00000007     58.5     29     48
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
595Q01369    316   GBLP_NEUCR Guanine nucleotide-binding protein...2700.0000002     57     21     43
596Q5F3D7    520   UTP15_CHICK U3 small nucleolar RNA-associated...1330.75     36.6     25     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
597Q6FT96    711   MDV1_CANGA Mitochondrial division protein 1 O...2480.0000002     57.8     24     42GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
598Q19124    578   A16L1_CAEEL Autophagic-related protein 16.1 O...1191.7     35.4     21     39
599Q8C6G8    641   WDR26_MOUSE WD repeat-containing protein 26 O...2650.00004     50.8     25     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
600Q6ZMW3    1958   EMAL6_HUMAN Echinoderm microtubule-associated...2380.74     37     24     37GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
601O94244    430   HAT2_SCHPO Histone acetyltransferase type B s...2270.00000000009     68.2     26     48GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031511; C:Mis6-Sim4 complex; TAS:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0034080; P:CenH3-containing nucleosome assembly at centromere; TAS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016575; P:histone deacetylation; IMP:PomBase.::GO:0051382; P:kinetochore assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0031066; P:regulation of histone deacetylation at centromere; IMP:PomBase.
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