Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR084C
Length:
713
Number of sequences:
5887
Description:
YCR084C TUP1 SGDID:S000000680, Chr III from 262452-260311, Genome Release 64-1-1, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q04727    773   TLE4_HUMAN Transducin-like enhancer protein 4...3320.000000000000001     84.3     26     41GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
302Q28YY2    680   WDR48_DROPS WD repeat-containing protein 48 h...3430.0000000000001     77.8     23     44
303B4GIJ0    680   WDR48_DROPE WD repeat-containing protein 48 h...3430.0000000000001     77.8     23     44
304Q9JIT3    764   TLE3_RAT Transducin-like enhancer protein 3 O...3660.000000000000001     84.3     24     39GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005515; F:protein binding; IPI:BHF-UCL.
GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
305Q62440    770   TLE1_MOUSE Transducin-like enhancer protein 1...3320.000000000000002     84.3     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
306Q08122    772   TLE3_MOUSE Transducin-like enhancer protein 3...3600.000000000000002     84.3     25     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
307Q9UMS4    504   PRP19_HUMAN Pre-mRNA-processing factor 19 OS=...2160.0001     48.9     23     38GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:BHF-UCL.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0000245; P:spliceosomal complex assembly; IMP:BHF-UCL.
308Q04726    772   TLE3_HUMAN Transducin-like enhancer protein 3...3600.000000000000002     84.3     25     39GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
309Q04724    770   TLE1_HUMAN Transducin-like enhancer protein 1...3320.000000000000002     84.3     26     40
GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
310Q5BLX8    315   WDR83_RAT WD repeat domain-containing protein...1880.00005     49.7     25     44GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
311B4KKN1    419   WDR12_DROMO Ribosome biogenesis protein WDR12...1722.9     34.7     23     45GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
312Q9JMJ4    504   PRP19_RAT Pre-mRNA-processing factor 19 OS=Ra...2160.00009     49.3     23     38GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
313Q99KP6    504   PRP19_MOUSE Pre-mRNA-processing factor 19 OS=...2160.00009     49.3     23     38GO:0005811; C:lipid particle; IDA:MGI.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0001833; P:inner cell mass cell proliferation; IMP:MGI.::GO:0008610; P:lipid biosynthetic process; IDA:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.::GO:0048711; P:positive regulation of astrocyte differentiation; IDA:MGI.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; IMP:MGI.
314Q4X1Y0    510   PFS2_ASPFU Polyadenylation factor subunit 2 O...1360.005     43.9     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
315O42478    772   TLE4_XENLA Transducin-like enhancer protein 4...3320.000000000000002     84     26     41GO:0017053; C:transcriptional repressor complex; IPI:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IGI:UniProtKB.
GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
316Q08E38    504   PRP19_BOVIN Pre-mRNA-processing factor 19 OS=...2160.00006     50.1     23     38GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
317Q9DAJ4    315   WDR83_MOUSE WD repeat domain-containing prote...1470.004     43.5     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
318A7MB12    519   UTP15_BOVIN U3 small nucleolar RNA-associated...814.7     34.3     27     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
319Q6PNB6    353   GBB5_RABIT Guanine nucleotide-binding protein...2410.00000006     58.9     24     41GO:0005634; C:nucleus; ISS:AgBase.::GO:0005886; C:plasma membrane; ISS:AgBase.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:AgBase.
320O14775    395   GBB5_HUMAN Guanine nucleotide-binding protein...2410.00000003     60.1     24     41GO:0005834; C:heterotrimeric G-protein complex; NAS:UniProtKB.
GO:0003924; F:GTPase activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:UniProtKB.
321A4R3M4    461   LIS1_MAGO7 Nuclear distribution protein PAC1 ...2050.0000000003     67     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
322Q9VU65    391   POC1_DROME POC1 centriolar protein homolog OS...1370.058     40     26     37
GO:0051297; P:centrosome organization; IMP:FlyBase.
323P53622    1201   COPA_YEAST Coatomer subunit alpha OS=Saccharo...2770.00000000000001     82     26     41GO:0030126; C:COPI vesicle coat; IMP:SGD.
GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
324Q5ZJH5    305   WDR61_CHICK WD repeat-containing protein 61 O...1350.1     38.9     27     46GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
325Q05B17    678   WDR48_XENTR WD repeat-containing protein 48 O...1190.0000002     58.2     29     54GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
326Q80ZD0    353   GBB5_TAMST Guanine nucleotide-binding protein...2410.00000006     58.9     24     41
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
327Q6PFM9    677   WDR48_DANRE WD repeat-containing protein 48 O...1190.0000004     57     29     52GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
328Q5RDY7    353   GBB5_PONAB Guanine nucleotide-binding protein...2410.00000006     58.9     24     41
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
329O94620    340   CWF17_SCHPO Pre-mRNA-splicing factor cwf17 OS...2090.03     40.8     22     44GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
330Q8L828    909   COB23_ARATH Coatomer subunit beta'-3 OS=Arabi...660.067     40.4     26     53GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
331Q7T2F6    423   WSB1_DANRE WD repeat and SOCS box-containing ...2340.00008     49.3     23     40
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
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