Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR084C
Length:
713
Number of sequences:
5887
Description:
YCR084C TUP1 SGDID:S000000680, Chr III from 262452-260311, Genome Release 64-1-1, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q291L9    411   LIS1_DROPS Lissencephaly-1 homolog OS=Drosoph...1690.000002     54.7     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
152B4GAJ1    411   LIS1_DROPE Lissencephaly-1 homolog OS=Drosoph...1690.000002     54.7     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
153P79147    340   GBB3_CANFA Guanine nucleotide-binding protein...1720.003     43.9     22     42GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
154Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...2960.00002     52     22     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
155Q12220    943   UTP12_YEAST U3 small nucleolar RNA-associated...1450.083     40     25     43GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
156Q09855    506   POF11_SCHPO F-box/WD repeat-containing protei...1120.00000004     60.1     34     55GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
157Q6P5M2    305   WDR61_DANRE WD repeat-containing protein 61 O...1350.0002     48.1     31     48GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
158Q0U1B1    462   LIS1_PHANO Nuclear distribution protein PAC1 ...3000.0000000000003     76.3     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
159A1CF18    435   LIS12_ASPCL Nuclear distribution protein nudF...1890.0003     47.4     28     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
160P93107    606   PF20_CHLRE Flagellar WD repeat-containing pro...850.16     38.9     25     45GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.
161Q2HJH6    358   SNR40_BOVIN U5 small nuclear ribonucleoprotei...1700.000000000002     72.8     29     48GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
162Q9BZK7    514   TBL1R_HUMAN F-box-like/WD repeat-containing p...1760.000009     52.8     26     47GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
163Q8NBT0    407   POC1A_HUMAN POC1 centriolar protein homolog A...1320.00005     50.1     27     45GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
164B2AEZ5    464   LIS11_PODAN Nuclear distribution protein PAC1...2990.0000000006     65.9     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
165Q95RJ9    700   EBI_DROME F-box-like/WD repeat-containing pro...2680.00000000002     71.2     22     39GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase.
GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
166Q7RY30    453   LIS11_NEUCR Nuclear distribution protein pac1...874     34.3     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
167Q2TBP4    407   POC1A_BOVIN POC1 centriolar protein homolog A...920.0002     48.1     33     49GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
168Q4R8H1    569   TBL1X_MACFA F-box-like/WD repeat-containing p...2450.00000000001     71.6     25     41GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
169Q00664    444   LIS1_EMENI Nuclear distribution protein nudF ...560.003     44.7     34     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
170Q6PE01    358   SNR40_MOUSE U5 small nuclear ribonucleoprotei...1700.000000000004     72     29     48
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
171Q96DI7    357   SNR40_HUMAN U5 small nuclear ribonucleoprotei...1700.000000000001     73.6     29     48GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005732; C:small nucleolar ribonucleoprotein complex; NAS:UniProtKB.::GO:0005682; C:U5 snRNP; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
172Q9BVA0    655   KTNB1_HUMAN Katanin p80 WD40-containing subun...1380.00004     50.8     25     45GO:0008352; C:katanin complex; TAS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0008017; F:microtubule binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0031117; P:positive regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0006605; P:protein targeting; NAS:UniProtKB.
173C6HTE8    456   LIS1_AJECH Nuclear distribution protein PAC1 ...550.015     42     31     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
174C0NRC6    456   LIS1_AJECG Nuclear distribution protein PAC1 ...550.015     42     31     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
175Q8BG40    658   KTNB1_MOUSE Katanin p80 WD40-containing subun...1380.00004     50.8     25     45GO:0030424; C:axon; IDA:MGI.::GO:0005813; C:centrosome; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0045502; F:dynein binding; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
176P20053    465   PRP4_YEAST U4/U6 small nuclear ribonucleoprot...2680.000000000001     74.3     25     46GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
177Q6NVM2    655   KTNB1_XENTR Katanin p80 WD40-containing subun...1380.000004     53.9     28     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
178P54313    340   GBB2_RAT Guanine nucleotide-binding protein G...2160.0000000002     66.6     25     42GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005246; F:calcium channel regulator activity; IMP:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
179P62880    340   GBB2_MOUSE Guanine nucleotide-binding protein...2160.0000000002     66.6     25     42GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI.
180P62879    340   GBB2_HUMAN Guanine nucleotide-binding protein...2160.0000000002     66.6     25     42GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
181P11017    340   GBB2_BOVIN Guanine nucleotide-binding protein...2160.0000000002     66.6     25     42GO:0005834; C:heterotrimeric G-protein complex; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0003924; F:GTPase activity; IDA:MGI.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
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