Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR084C
Length:
713
Number of sequences:
5887
Description:
YCR084C TUP1 SGDID:S000000680, Chr III from 262452-260311, Genome Release 64-1-1, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121B4HSL3    411   LIS1_DROSE Lissencephaly-1 homolog OS=Drosoph...1690.000004     53.5     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
122Q7KNS3    411   LIS1_DROME Lissencephaly-1 homolog OS=Drosoph...1690.000004     53.5     27     39GO:0030424; C:axon; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005869; C:dynactin complex; IDA:FlyBase.::GO:0030286; C:dynein complex; IDA:FlyBase.::GO:0005828; C:kinetochore microtubule; IDA:FlyBase.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0031616; C:spindle pole centrosome; IDA:FlyBase.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0008088; P:axon cargo transport; IMP:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IMP:UniProtKB.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:UniProtKB.::GO:0048142; P:germarium-derived cystoblast division; IMP:UniProtKB.::GO:0007294; P:germarium-derived oocyte fate determination; IMP:UniProtKB.::GO:0008298; P:intracellular mRNA localization; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:FlyBase.::GO:0051383; P:kinetochore organization; IMP:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:UniProtKB.::GO:0007405; P:neuroblast proliferation; IMP:UniProtKB.::GO:0030473; P:nuclear migration along microtubule; IGI:FlyBase.::GO:0007312; P:oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:UniProtKB.::GO:0030510; P:regulation of BMP signaling pathway; IDA:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.::GO:0043143; P:regulation of translation by machinery localization; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:FlyBase.::GO:0019827; P:stem cell maintenance; IDA:FlyBase.
123O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...2450.00000000001     71.6     25     41GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
124A8XZJ9    390   LIS1_CAEBR Lissencephaly-1 homolog OS=Caenorh...1690.099     39.3     21     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
125Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...2000.00002     52     23     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
126B4LQ21    411   LIS1_DROVI Lissencephaly-1 homolog OS=Drosoph...1690.000001     55.1     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
127A0DB19    403   LIS11_PARTE Lissencephaly-1 homolog 1 OS=Para...996.2     33.5     27     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
128B4P6P9    411   LIS1_DROYA Lissencephaly-1 homolog OS=Drosoph...1690.000005     53.1     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
129B3NPW0    411   LIS1_DROER Lissencephaly-1 homolog OS=Drosoph...1690.000005     53.1     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
130Q4V7Y7    655   KTNB1_XENLA Katanin p80 WD40-containing subun...1380.000004     53.9     28     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
131B4MY65    409   LIS1_DROWI Lissencephaly-1 homolog OS=Drosoph...1690.000002     54.7     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
132P62884    312   GBLP_LEIIN Guanine nucleotide-binding protein...780.4     37.4     27     44
133P62883    312   GBLP_LEICH Guanine nucleotide-binding protein...780.4     37.4     27     44
134D4D8P3    663   SCONB_TRIVH Probable E3 ubiquitin ligase comp...1340.0007     46.6     23     43
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
135O13615    473   PRP46_SCHPO Pre-mRNA-splicing factor prp5 OS=...2653e-16     85.9     27     43GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IMP:PomBase.
136D4AM37    663   SCONB_ARTBC Probable E3 ubiquitin ligase comp...1340.0007     46.6     23     43
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
137A0CH87    403   LIS12_PARTE Lissencephaly-1 homolog 2 OS=Para...2320.000000002     63.9     25     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
138Q7SZM9    519   TB1RA_XENLA F-box-like/WD repeat-containing p...1760.000005     53.5     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
139P0CS48    473   PRP46_CRYNJ Pre-mRNA-splicing factor PRP46 OS...2343e-17     89     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
140P0CS49    473   PRP46_CRYNB Pre-mRNA-splicing factor PRP46 OS...2343e-17     89     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
141C5FP68    674   SCONB_ARTOC Probable E3 ubiquitin ligase comp...1320.83     36.6     25     45
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
142Q4ICM0    464   LIS1_GIBZE Nuclear distribution protein PAC1 ...550.001     45.8     40     62GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
143P49846    704   TAF5_DROME Transcription initiation factor TF...2570.000000000002     74.3     29     42GO:0000124; C:SAGA complex; IPI:FlyBase.::GO:0005669; C:transcription factor TFIID complex; IDA:FlyBase.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IDA:GOC.
144Q25306    312   GBLP_LEIMA Guanine nucleotide-binding protein...1370.11     38.9     28     41
145B3MEY6    411   LIS1_DROAN Lissencephaly-1 homolog OS=Drosoph...1690.000001     55.5     27     38GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
146A7EKM8    458   LIS1_SCLS1 Nuclear distribution protein PAC1 ...863     34.7     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
147Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...2600.000009     52.8     22     41
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
148Q6GPC6    522   TB1RB_XENLA F-box-like/WD repeat-containing p...1760.000005     53.5     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
149Q8BHJ5    514   TBL1R_MOUSE F-box-like/WD repeat-containing p...2680.0000000005     66.2     22     41
GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
150B4KT48    411   LIS1_DROMO Lissencephaly-1 homolog OS=Drosoph...1690.000002     54.7     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
151Q291L9    411   LIS1_DROPS Lissencephaly-1 homolog OS=Drosoph...1690.000002     54.7     27     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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