UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YCR072C

Length:

515

Number of sequences:

5887

Description:

YCR072C RSA4 SGDID:S000000668, Chr III from 242352-240805, Genome Release 64-1-1, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	C5JD40	473	LIS1_AJEDS Nuclear distribution protein PAC1 ...	274	0.000000000005	71.6	25	37	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
152	C5GVJ9	473	LIS1_AJEDR Nuclear distribution protein PAC1 ...	274	0.000000000005	71.6	25	37	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
153	O76734	579	TUP1_DICDI General transcriptional corepresso...	80	0.00004	50.1	36	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
154	A4R3M4	461	LIS1_MAGO7 Nuclear distribution protein PAC1 ...	136	0.00000001	60.8	29	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
155	Q8BHJ5	514	TBL1R_MOUSE F-box-like/WD repeat-containing p...	112	0.0000002	57.4	29	54
									GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
156	Q9BZK7	514	TBL1R_HUMAN F-box-like/WD repeat-containing p...	112	0.0000002	57.4	29	54	GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
									GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
									GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
157	Q229Z6	634	POC1_TETTS POC1 centriolar protein homolog OS...	172	0.000000000000003	82	30	48	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
									GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0051297; P:centrosome organization; IMP:UniProtKB.
158	P78706	604	RCO1_NEUCR Transcriptional repressor rco-1 OS...	141	0.00000002	60.1	28	50
									GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
159	B6QC06	452	LIS12_PENMQ Nuclear distribution protein nudF...	124	0.0000005	55.8	31	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
160	B8P4B0	438	LIS11_POSPM Nuclear distribution protein PAC1...	75	0.00005	49.3	35	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
161	Q61FW2	589	SEL10_CAEBR F-box/WD repeat-containing protei...	338	7e-20	96.7	26	44
162	D1ZEM6	486	LIS12_SORMK Nuclear distribution protein PAC1...	138	0.00000009	58.2	31	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
163	O43017	380	SWD3_SCHPO Set1 complex component swd3 OS=Sch...	150	0.00000002	60.1	24	50	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase.
									GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase.
164	Q4R8H1	569	TBL1X_MACFA F-box-like/WD repeat-containing p...	112	0.0000005	55.8	29	53	GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
									GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
									GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
165	B6Q4Z5	660	SCONB_PENMQ Probable E3 ubiquitin ligase comp...	184	0.0000001	58.2	27	45
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
166	B8M0Q1	459	LIS1_TALSN Nuclear distribution protein nudF ...	77	3.9	33.9	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
167	O88879	1249	APAF_MOUSE Apoptotic protease-activating fact...	339	0.0000002	57.8	22	38	GO:0005634; C:nucleus; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0016505; F:apoptotic protease activator activity; IPI:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.
									GO:0006952; P:defense response; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
168	C5FWH1	461	LIS1_ARTOC Nuclear distribution protein PAC1 ...	89	0.000000005	62	36	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
169	Q93847	395	YZLL_CAEEL Uncharacterized WD repeat-containi...	81	0.015	41.2	30	52
170	Q7SZM9	519	TB1RA_XENLA F-box-like/WD repeat-containing p...	112	0.0000002	57	29	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
171	Q6GPC6	522	TB1RB_XENLA F-box-like/WD repeat-containing p...	112	0.0000002	57.4	29	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
172	O60907	577	TBL1X_HUMAN F-box-like/WD repeat-containing p...	112	0.0000004	56.2	29	54	GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
									GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
									GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
173	Q9UUG8	598	TUP12_SCHPO Transcriptional repressor tup12 O...	299	0.0000000000003	75.9	25	40	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IDA:PomBase.
									GO:0043156; P:chromatin remodeling in response to cation stress; IMP:PomBase.::GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
174	Q5RF51	357	SNR40_PONAB U5 small nuclear ribonucleoprotei...	123	0.00000000002	69.3	34	54	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
175	B6QC56	459	LIS11_PENMQ Nuclear distribution protein nudF...	123	0.000000002	63.2	33	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
176	C5PFX0	471	LIS1_COCP7 Nuclear distribution protein PAC1 ...	274	0.0000000006	65.1	24	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
177	Q93794	587	SEL10_CAEEL F-box/WD repeat-containing protei...	77	0.021	41.2	34	51	GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.
178	Q9EPV5	1249	APAF_RAT Apoptotic protease-activating factor...	218	0.003	44.3	21	42	GO:0043293; C:apoptosome; IDA:RGD.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.
									GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0010659; P:cardiac muscle cell apoptotic process; IMP:RGD.::GO:0030154; P:cell differentiation; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0006952; P:defense response; IEA:InterPro.::GO:0034349; P:glial cell apoptotic process; IEP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0051260; P:protein homooligomerization; IDA:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
179	O14727	1248	APAF_HUMAN Apoptotic protease-activating fact...	238	0.008	42.7	21	38	GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc.
180	Q0D0X6	446	LIS1_ASPTN Nuclear distribution protein nudF ...	132	0.000002	53.9	29	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
181	Q00664	444	LIS1_EMENI Nuclear distribution protein nudF ...	124	0.000002	53.9	28	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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