Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P10862    487   RAD18_YEAST Postreplication repair E3 ubiquit...4870     1009     100     100GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IPI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042275; P:error-free postreplication DNA repair; IGI:SGD.::GO:0070987; P:error-free translesion synthesis; IGI:SGD.::GO:0042276; P:error-prone translesion synthesis; IGI:SGD.::GO:0006513; P:protein monoubiquitination; IMP:SGD.
2Q6FPI4    411   RAD18_CANGA Postreplication repair E3 ubiquit...4214e-110     339     45     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
3Q75EN0    443   RAD18_ASHGO Postreplication repair E3 ubiquit...4071e-94     300     42     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
4Q6CTZ8    427   RAD18_KLULA Postreplication repair E3 ubiquit...4188e-85     274     40     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
5Q6BLM3    491   RAD18_DEBHA Postreplication repair E3 ubiquit...4261e-45     171     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
6Q5A4N5    378   RAD18_CANAL Postreplication repair E3 ubiquit...3743e-41     156     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
7O74747    387   RAD18_SCHPO Postreplication repair E3 ubiquit...3984e-39     150     29     45GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000077; P:DNA damage checkpoint; IMP:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0031144; P:proteasome localization; IMP:PomBase.
8P33288    501   RAD18_NEUCR Postreplication repair E3 ubiquit...4237e-34     137     26     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
9Q02398    443   RAD18_EMENI Postreplication repair E3 ubiquit...4174e-27     116     25     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
10Q4WZJ6    418   RAD18_ASPFU Postreplication repair E3 ubiquit...3911e-24     108     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
11Q9QXK2    509   RAD18_MOUSE E3 ubiquitin-protein ligase RAD18...3381e-20     98.2     28     46GO:0000785; C:chromatin; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001741; C:XY body; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.::GO:0009411; P:response to UV; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.
12Q6CHI1    344   RAD18_YARLI Postreplication repair E3 ubiquit...1360.000009     51.2     21     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
13P93471    672   COP1_PEA E3 ubiquitin-protein ligase COP1 OS=...800.000000001     64.3     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
14Q9NS91    495   RAD18_HUMAN E3 ubiquitin-protein ligase RAD18...1250.00000003     59.7     34     54GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005657; C:replication fork; IDA:UniProtKB.
GO:0003684; F:damaged DNA binding; NAS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; NAS:UniProtKB.
15P43254    675   COP1_ARATH E3 ubiquitin-protein ligase COP1 O...2370.000000004     62.4     24     40GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000152; C:nuclear ubiquitin ligase complex; TAS:TAIR.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046283; P:anthocyanin metabolic process; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0009649; P:entrainment of circadian clock; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IGI:TAIR.::GO:0048573; P:photoperiodism, flowering; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009641; P:shade avoidance; IMP:TAIR.::GO:0009647; P:skotomorphogenesis; TAS:TAIR.
16Q1L5Z9    754   LONF2_HUMAN LON peptidase N-terminal domain a...640.0000007     55.5     42     53
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
17Q03605    160   YNN1_CAEEL Uncharacterized RING finger protei...380.0000009     52.4     47     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
18Q17RB8    773   LONF1_HUMAN LON peptidase N-terminal domain a...230.86     35.8     57     70
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
19Q99PN3    545   TRI26_MOUSE Tripartite motif-containing prote...760.000002     53.5     34     55GO:0005737; C:cytoplasm; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
20P62603    542   TRI26_RAT Tripartite motif-containing protein...760.000003     53.5     34     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
21O60106    486   YOXA_SCHPO LON peptidase N-terminal domain an...730.000003     53.1     34     48
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006508; P:proteolysis; IEA:InterPro.
22Q7YR34    539   TRI26_PANTR Tripartite motif-containing prote...820.000005     52.8     33     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q12899    539   TRI26_HUMAN Tripartite motif-containing prote...820.000005     52.8     33     55
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
24Q12161    406   PSH1_YEAST RING finger protein PSH1 OS=Saccha...510.000009     51.6     43     59GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.
25Q4P3X7    817   BRE1_USTMA E3 ubiquitin-protein ligase BRE1 O...490.00001     51.6     43     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
26Q9UTL9    1375   YIV5_SCHPO Uncharacterized ATP-dependent heli...380.00002     50.8     42     63GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:PomBase.
27O54952    1817   BRCA1_RAT Breast cancer type 1 susceptibility...700.00003     50.4     33     51GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:RGD.
GO:0003684; F:damaged DNA binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007420; P:brain development; IEP:RGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
28Q8N448    690   LNX2_HUMAN Ligand of Numb protein X 2 OS=Homo...440.00003     50.1     50     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
29Q91XL2    687   LNX2_MOUSE Ligand of Numb protein X 2 OS=Mus ...440.00003     50.1     50     61
GO:0030165; F:PDZ domain binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051260; P:protein homooligomerization; IDA:MGI.
30O77666    545   TRI26_PIG Tripartite motif-containing protein...820.00004     49.7     33     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
31Q9D4H7    753   LONF3_MOUSE LON peptidase N-terminal domain a...400.033     40.4     43     48
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
records
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