Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q6J6I9    1863   BRCA1_MACMU Breast cancer type 1 susceptibili...670.0006     46.2     31     51GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
62Q2HJ46    487   RNF8_BOVIN E3 ubiquitin-protein ligase RNF8 O...440.0006     45.8     36     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
63Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...580.0007     45.8     38     52GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
64O13033    1057   RAG1_DANRE V(D)J recombination-activating pro...580.0007     46.2     38     52GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
65Q9UPQ7    1066   PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN...420.0007     46.2     38     62
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
66A0JN74    468   TRI11_BOVIN E3 ubiquitin-protein ligase TRIM1...820.0007     45.8     33     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009615; P:response to virus; IEA:UniProtKB-KW.
67Q69ZS0    1063   PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN...420.0007     45.8     38     62GO:0031594; C:neuromuscular junction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007528; P:neuromuscular junction development; IMP:UniProtKB.
68Q8NG06    486   TRI58_HUMAN Tripartite motif-containing prote...710.0008     45.4     34     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
69O75382    744   TRIM3_HUMAN Tripartite motif-containing prote...700.0008     45.8     33     54GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
70Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...580.0008     45.8     38     52GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
71Q9BVG3    475   TRI62_HUMAN Tripartite motif-containing prote...840.0008     45.4     32     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
72Q80X56    500   TRI69_MOUSE Tripartite motif-containing prote...630.0009     45.4     38     56GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
73Q86SE9    256   PCGF5_HUMAN Polycomb group RING finger protei...640.0009     44.7     38     55GO:0005813; C:centrosome; IDA:LIFEdb.::GO:0031519; C:PcG protein complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q5W0B1    726   RN219_HUMAN RING finger protein 219 OS=Homo s...400.001     45.4     43     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
75Q9R1R2    744   TRIM3_MOUSE Tripartite motif-containing prote...700.001     45.4     33     54GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
76Q5RD97    726   RN219_PONAB RING finger protein 219 OS=Pongo ...400.001     45.4     43     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
77Q91YT2    192   RN185_MOUSE E3 ubiquitin-protein ligase RNF18...460.001     43.9     41     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
78Q9WUH5    489   TRI10_MOUSE Tripartite motif-containing prote...990.001     45.4     26     43GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; IDA:MGI.
79O76064    485   RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 O...440.001     45.1     36     55GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
80Q8VI40    466   TRI60_MOUSE Tripartite motif-containing prote...410.001     45.1     44     59GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
81O70277    744   TRIM3_RAT Tripartite motif-containing protein...700.001     45.4     33     54GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
82Q5R4I2    486   RNF8_PONAB E3 ubiquitin-protein ligase RNF8 O...440.001     45.1     36     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
83A6NK02    468   TRI75_HUMAN Tripartite motif-containing prote...790.001     45.1     33     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
84Q8RXD4    941   BRCA1_ARATH Protein BREAST CANCER SUSCEPTIBIL...930.001     45.4     23     42GO:0005634; C:nucleus; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0010332; P:response to gamma radiation; IEP:TAIR.
85Q7S304    707   BRE1_NEUCR E3 ubiquitin-protein ligase bre-1 ...450.001     45.1     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
86Q8K2Y0    722   RN219_MOUSE RING finger protein 219 OS=Mus mu...400.001     45.1     43     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
87Q06554    1556   IRC20_YEAST Uncharacterized ATP-dependent hel...410.001     45.4     39     54GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:SGD.
88Q4WUA0    339   CWC24_ASPFU Pre-mRNA-splicing factor cwc24 OS...400.001     44.7     40     48GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
89Q9SYU4    381   PEX10_ARATH Peroxisome biogenesis factor 10 O...390.001     44.7     44     54GO:0005829; C:cytosol; IDA:TAIR.::GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010381; P:attachment of peroxisome to chloroplast; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0009853; P:photorespiration; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IMP:TAIR.
90Q80V85    475   TRI62_MOUSE Tripartite motif-containing prote...840.001     44.7     31     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
91P97868    1790   RBBP6_MOUSE E3 ubiquitin-protein ligase RBBP6...460.001     45.1     46     63GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
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