Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q69Z36    601   MEX3B_MOUSE RNA-binding protein MEX3B OS=Mus ...402.7     34.3     38     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
542Q9D0C1    305   RN115_MOUSE E3 ubiquitin-protein ligase RNF11...592.9     33.9     36     49GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
543Q9P2G1    1089   AKIB1_HUMAN Ankyrin repeat and IBR domain-con...393     34.3     49     54
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
544Q9M0R7    132   ATL39_ARATH RING-H2 finger protein ATL39 OS=A...443.2     32.7     32     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
545Q6ZN04    569   MEX3B_HUMAN RNA-binding protein MEX3B OS=Homo...403.2     33.9     38     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
546Q7SZN2    266   RN170_DANRE RING finger protein 170 OS=Danio ...513.3     33.5     31     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009790; P:embryo development; IMP:ZFIN.
547Q9BYJ4    488   TRI34_HUMAN Tripartite motif-containing prote...733.3     33.9     25     47GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070206; P:protein trimerization; IDA:UniProtKB.
548P93748    305   SINA1_ARATH Putative E3 ubiquitin-protein lig...463.4     33.5     39     50GO:0005634; C:nucleus; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
549Q96T88    793   UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1...553.4     33.9     25     47GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IEP:BHF-UCL.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.::GO:2000373; P:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; IC:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
550Q9ULV8    474   CBLC_HUMAN Signal transduction protein CBL-C ...453.5     33.9     38     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.::GO:0001784; F:phosphotyrosine binding; IDA:BHF-UCL.::GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
551Q7XZZ3    339   BAHL1_ORYSJ Probable E3 ubiquitin-protein lig...723.5     33.5     31     40
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
552A2XK56    339   BAHL1_ORYSI Probable E3 ubiquitin-protein lig...723.5     33.5     31     40
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
553Q6ZPS6    1085   AKIB1_MOUSE Ankyrin repeat and IBR domain-con...393.5     33.9     49     51
GO:0008270; F:zinc ion binding; IEA:InterPro.
554Q920M2    352   RNF39_RAT RING finger protein 39 OS=Rattus no...833.7     33.5     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048168; P:regulation of neuronal synaptic plasticity; NAS:RGD.
555O60291    552   MGRN1_HUMAN E3 ubiquitin-protein ligase MGRN1...473.7     33.9     34     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.::GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.::GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IMP:UniProtKB.
556Q3V3A7    635   RN207_MOUSE RING finger protein 207 OS=Mus mu...413.7     33.9     37     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
557P08393    775   ICP0_HHV11 E3 ubiquitin-protein ligase ICP0 O...423.8     33.9     38     52GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:AgBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; TAS:AgBase.::GO:0000209; P:protein polyubiquitination; IDA:AgBase.::GO:0019046; P:reactivation of latent virus; TAS:AgBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0034340; P:response to type I interferon; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
558A8WWR3    578   HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-l...393.8     33.9     33     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
559Q9LSW9    375   ATL16_ARATH RING-H2 finger protein ATL16 OS=A...423.9     33.5     38     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
560P86449    446   TR43C_MOUSE Tripartite motif-containing prote...433.9     33.5     35     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
561Q9M0R6    302   ATL35_ARATH Putative RING-H2 finger protein A...444     33.5     39     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
562Q6INH1    674   RN157_XENLA RING finger protein 157 OS=Xenopu...524     33.9     31     44
GO:0008270; F:zinc ion binding; IEA:InterPro.
563Q9D074    532   MGRN1_MOUSE E3 ubiquitin-protein ligase MGRN1...474.1     33.5     34     47GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043951; P:negative regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:MGI.
564A6NCD1    456   TRIX2_HUMAN Tripartite motif-containing prote...344.2     33.5     44     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
565Q5XIQ4    533   MGRN1_RAT E3 ubiquitin-protein ligase MGRN1 O...474.2     33.5     34     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043951; P:negative regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.
566Q9Y4L5    304   RN115_HUMAN E3 ubiquitin-protein ligase RNF11...594.3     33.5     36     47GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
567O44406    582   ERI1_CAEEL 3'-5' exonuclease eri-1 OS=Caenorh...644.3     33.5     30     48GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0000175; F:3'-5'-exoribonuclease activity; IDA:WormBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0048609; P:multicellular organismal reproductive process; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006401; P:RNA catabolic process; IDA:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.
568Q9FPH0    376   XB34_ARATH Putative E3 ubiquitin-protein liga...394.6     33.5     38     49
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
569Q8TFH8    343   PEX12_SCHPO Peroxisome assembly protein 12 OS...384.9     33.1     37     50GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008022; F:protein C-terminus binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006625; P:protein targeting to peroxisome; IEA:InterPro.
570Q96GC6    653   ZN274_HUMAN Neurotrophin receptor-interacting...1285     33.5     27     41GO:0005813; C:centrosome; IDA:HPA.::GO:0005730; C:nucleolus; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
571Q22122    322   ZC21A_CAEEL Zinc finger C2HC domain-containin...385     33.1     45     55
records
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