Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q2YEM9    493   TRIM5_PONPY Tripartite motif-containing prote...740.45     36.6     26     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
422Q5C8T8    493   TRIM5_PONAB Tripartite motif-containing prote...740.45     36.6     26     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
423Q80XL1    496   CBLC_MOUSE Signal transduction protein CBL-C ...1220.46     36.6     26     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
424Q3U319    1001   BRE1B_MOUSE E3 ubiquitin-protein ligase BRE1B...450.46     37     40     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
425Q4R7K7    1001   BRE1B_MACFA E3 ubiquitin-protein ligase BRE1B...450.46     37     40     42GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
426Q5RAU7    1001   BRE1B_PONAB E3 ubiquitin-protein ligase BRE1B...450.47     37     40     42GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
427Q2YEN2    497   TRIM5_MACAS Tripartite motif-containing prote...730.48     36.6     25     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
428Q6BIP2    1190   RAD5_DEBHA DNA repair protein RAD5 OS=0083 / ...470.49     37     38     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
429Q99942    180   RNF5_HUMAN E3 ubiquitin-protein ligase RNF5 O...430.49     35.8     33     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
430Q6Q0C0    670   TRAF7_HUMAN E3 ubiquitin-protein ligase TRAF7...260.5     36.6     54     62GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IDA:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
431Q9FF61    881   SM3L1_ARATH Putative SWI/SNF-related matrix-a...520.5     36.6     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
432O75150    1001   BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B...450.51     36.6     40     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0019717; C:synaptosome; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
433Q6P256    626   CHFR_XENTR E3 ubiquitin-protein ligase CHFR O...590.51     36.6     36     49GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
434Q0PF16    497   TRIM5_MACMU Tripartite motif-containing prote...730.51     36.6     25     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
435Q5NCC3    630   TRI41_MOUSE E3 ubiquitin-protein ligase TRIM4...250.52     36.6     48     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
436Q9H270    941   VPS11_HUMAN Vacuolar protein sorting-associat...480.52     36.6     35     56GO:0030139; C:endocytic vesicle; IDA:UniProtKB.::GO:0030897; C:HOPS complex; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
437P23798    342   PCGF2_MOUSE Polycomb group RING finger protei...480.52     36.2     31     50GO:0016604; C:nuclear body; IDA:MGI.::GO:0035102; C:PRC1 complex; ISS:UniProtKB.::GO:0001739; C:sex chromatin; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0016573; P:histone acetylation; IGI:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
438Q2KJ29    242   PCGF3_BOVIN Polycomb group RING finger protei...550.52     35.8     29     47GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
439Q91W86    941   VPS11_MOUSE Vacuolar protein sorting-associat...480.52     36.6     35     56GO:0005884; C:actin filament; IDA:MGI.::GO:0005769; C:early endosome; IDA:MGI.::GO:0030139; C:endocytic vesicle; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
440Q5PPX5    257   RN170_XENLA RING finger protein 170 OS=Xenopu...570.53     35.8     33     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
441Q63HN8    5207   RN213_HUMAN E3 ubiquitin-protein ligase RNF21...400.55     37     43     48GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
442Q96K19    258   RN170_HUMAN RING finger protein 170 OS=Homo s...500.57     35.8     36     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
443Q6ZMU5    477   TRI72_HUMAN Tripartite motif-containing prote...710.57     36.2     24     41GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
444Q5FWP4    625   CHFR_XENLA E3 ubiquitin-protein ligase CHFR O...590.57     36.6     36     49GO:0016605; C:PML body; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
445Q587N6    495   TRIM5_MACFA Tripartite motif-containing prote...730.58     36.2     25     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
446Q99PD2    209   RN138_RAT E3 ubiquitin-protein ligase RNF138 ...520.58     35.8     40     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
447Q9UPQ4    493   TRI35_HUMAN Tripartite motif-containing prote...420.58     36.2     38     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
448Q5RAK3    592   RN180_PONAB E3 ubiquitin-protein ligase RNF18...420.59     36.6     40     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
449Q07G17    242   PCGF3_XENTR Polycomb group RING finger protei...550.59     35.8     29     47GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
450Q6IWL4    542   TRAF6_DANRE TNF receptor-associated factor 6 ...440.6     36.2     41     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; IMP:ZFIN.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:ZFIN.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0009617; P:response to bacterium; IDA:ZFIN.::GO:0009615; P:response to virus; IDA:ZFIN.::GO:0007165; P:signal transduction; IEA:InterPro.
451Q5RBG2    492   TRI35_PONAB Tripartite motif-containing prote...420.6     36.2     38     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
records
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