Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q96DY5    654   RN112_MOUSE RING finger protein 112 OS=Mus mu...410.33     37.4     41     49GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
392Q5R8L2    326   BMI1_PONAB Polycomb complex protein BMI-1 OS=...480.33     37     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
393P35226    326   BMI1_HUMAN Polycomb complex protein BMI-1 OS=...480.33     37     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0035102; C:PRC1 complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0030097; P:hemopoiesis; IEP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0007379; P:segment specification; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
394Q8C006    501   TRI35_MOUSE Tripartite motif-containing prote...840.33     37     27     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.
395Q32KX7    326   BMI1_BOVIN Polycomb complex protein BMI-1 OS=...480.34     37     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
396Q5SDR3    326   BMI1_CHICK Polycomb complex protein BMI-1 OS=...480.34     37     31     50GO:0031519; C:PcG protein complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
397P15919    1040   RAG1_MOUSE V(D)J recombination-activating pro...430.34     37.4     40     51GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0004519; F:endonuclease activity; IMP:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:MGI.::GO:0070244; P:negative regulation of thymocyte apoptotic process; IMP:MGI.::GO:0002331; P:pre-B cell allelic exclusion; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; IMP:UniProtKB.::GO:0033151; P:V(D)J recombination; IMP:UniProtKB.
398O70418    631   RN112_RAT RING finger protein 112 OS=Rattus n...410.34     37.4     41     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:RGD.
399Q60YN5    828   BRE1_CAEBR E3 ubiquitin-protein ligase bre-1 ...460.35     37.4     37     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
400P35227    344   PCGF2_HUMAN Polycomb group RING finger protei...480.35     37     31     50GO:0035102; C:PRC1 complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
401Q9Y7K6    741   YGI4_SCHPO Uncharacterized RING finger protei...720.36     37.4     33     44GO:0005634; C:nucleus; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006325; P:chromatin organization; ISS:PomBase.::GO:0006342; P:chromatin silencing; ISS:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
402Q9TST0    326   BMI1_FELCA Polycomb complex protein BMI-1 OS=...480.36     37     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031519; C:PcG protein complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
403Q5UPZ3    659   YR311_MIMIV Putative RING finger protein R311...410.36     37     39     56
GO:0008270; F:zinc ion binding; IEA:InterPro.
404Q3MV19    556   TRF6A_XENLA TNF receptor-associated factor 6-...440.36     37     43     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
405B0BLU1    535   RN168_XENTR E3 ubiquitin-protein ligase RNF16...390.37     37     38     51GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
406Q8CJB9    1002   BRE1B_RAT E3 ubiquitin-protein ligase BRE1B O...450.37     37.4     40     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017075; F:syntaxin-1 binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:RGD.
407A0JPQ4    477   TRI72_RAT Tripartite motif-containing protein...710.37     37     24     41GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
408Q96A61    297   TRI52_HUMAN Tripartite motif-containing prote...250.39     36.6     52     60GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
409Q3TL54    445   TR43A_MOUSE Tripartite motif-containing prote...520.39     37     31     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
410Q9C030    488   TRIM6_HUMAN Tripartite motif-containing prote...760.4     37     29     46GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070206; P:protein trimerization; IDA:UniProtKB.
411Q60MF5    836   RN207_CAEBR Probable RING finger protein 207 ...400.4     37     43     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
412P34537    837   BRE1_CAEEL E3 ubiquitin-protein ligase bre-1 ...460.41     37     37     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006664; P:glycolipid metabolic process; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
413Q5D7I2    494   TRIM5_PITPI Tripartite motif-containing prote...640.42     37     30     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
414P28284    825   ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 O...410.42     37     37     54
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
415P15918    1043   RAG1_HUMAN V(D)J recombination-activating pro...430.42     37     40     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
416Q8TDB6    740   DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L...390.43     37     41     54GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.
417Q8WV44    630   TRI41_HUMAN E3 ubiquitin-protein ligase TRIM4...250.44     37     48     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
418Q86T96    592   RN180_HUMAN E3 ubiquitin-protein ligase RNF18...420.44     37     40     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
419Q6INS5    557   RN168_XENLA E3 ubiquitin-protein ligase RNF16...390.44     37     38     51GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
420Q3KNV8    242   PCGF3_HUMAN Polycomb group RING finger protei...550.44     36.2     29     47GO:0031519; C:PcG protein complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
421Q2YEM9    493   TRIM5_PONPY Tripartite motif-containing prote...740.45     36.6     26     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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