Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361O80927    235   ATL33_ARATH RING-H2 finger protein ATL33 OS=A...260.23     37     54     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
362E7FAP1    630   RN169_DANRE E3 ubiquitin-protein ligase RNF16...400.23     37.7     45     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
363Q5ZLS3    984   BRE1A_CHICK E3 ubiquitin-protein ligase BRE1A...450.23     37.7     40     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
364Q07457    700   BRE1_YEAST E3 ubiquitin-protein ligase BRE1 O...510.24     37.7     31     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:SGD.::GO:0010390; P:histone monoubiquitination; IMP:SGD.::GO:0031573; P:intra-S DNA damage checkpoint; IMP:SGD.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:SGD.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; IMP:SGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IGI:SGD.
365Q5D7I5    494   TRIM5_CEBPY Tripartite motif-containing prote...640.24     37.7     31     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
366Q5RF77    571   CHFR_PONAB E3 ubiquitin-protein ligase CHFR O...460.24     37.7     39     52GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
367Q5DTM8    973   BRE1A_MOUSE E3 ubiquitin-protein ligase BRE1A...410.25     37.7     41     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
368Q867B5    1043   RAG1_PIG V(D)J recombination-activating prote...430.25     37.7     40     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
369Q95SP2    626   HRD1_DROME E3 ubiquitin-protein ligase HRD1 O...500.25     37.7     36     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016881; F:acid-amino acid ligase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.
370Q5D7J1    493   TRIM5_PANTR Tripartite motif-containing prote...720.26     37.4     26     51GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
371P25916    324   BMI1_MOUSE Polycomb complex protein BMI-1 OS=...2120.27     37.4     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016604; C:nuclear body; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007420; P:brain development; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0016573; P:histone acetylation; IGI:MGI.::GO:0016574; P:histone ubiquitination; IDA:MGI.::GO:0006959; P:humoral immune response; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:HGNC.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IMP:HGNC.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0021903; P:rostrocaudal neural tube patterning; IMP:MGI.::GO:0048103; P:somatic stem cell division; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
372Q3UIR3    748   DTX3L_MOUSE E3 ubiquitin-protein ligase DTX3L...430.27     37.7     40     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.
373Q6CF78    700   BRE1_YARLI E3 ubiquitin-protein ligase BRE1 O...460.27     37.7     33     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
374P86448    445   TR43B_MOUSE Tripartite motif-containing prote...520.27     37.4     31     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
375Q640D5    323   BMI1B_XENLA Polycomb complex protein BMI-1-B ...540.28     37     33     50GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
376Q8BTQ0    241   PCGF3_MOUSE Polycomb group RING finger protei...550.28     37     29     47GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
377Q1ACD8    493   TRIM5_PANPA Tripartite motif-containing prote...720.28     37.4     26     51GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
378Q6DLV9    243   PCGF1_RAT Polycomb group RING finger protein ...460.29     36.6     35     50GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
379Q54S31    374   PEX10_DICDI Peroxisome biogenesis factor 10 O...390.29     37.4     38     51GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
380Q7ZW16    318   RNF41_DANRE E3 ubiquitin-protein ligase NRDP1...450.29     37     40     51
GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030318; P:melanocyte differentiation; IMP:ZFIN.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
381P34088    1042   RAG1_RABIT V(D)J recombination-activating pro...430.29     37.7     40     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
382P29129    410   ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 O...430.29     37.4     40     47
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
383Q5M807    180   RNF5_RAT E3 ubiquitin-protein ligase RNF5 OS=...430.3     36.2     33     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
384O35445    180   RNF5_MOUSE E3 ubiquitin-protein ligase RNF5 O...430.3     36.2     33     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071712; P:ER-associated misfolded protein catabolic process; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
385Q20798    610   HRD1_CAEEL E3 ubiquitin-protein ligase hrd-1 ...600.3     37.4     33     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
386Q96A37    237   RN166_HUMAN RING finger protein 166 OS=Homo s...500.31     36.6     40     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
387Q5RKG6    501   TRI35_RAT Tripartite motif-containing protein...840.32     37.4     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
388Q9C035    493   TRIM5_HUMAN Tripartite motif-containing prote...720.32     37.4     26     51GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
389Q5C8T6    493   TRIM5_GORGO Tripartite motif-containing prote...720.32     37.4     26     51GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
390O00463    557   TRAF5_HUMAN TNF receptor-associated factor 5 ...460.33     37.4     39     50GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
391Q96DY5    654   RN112_MOUSE RING finger protein 112 OS=Mus mu...410.33     37.4     41     49GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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