Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q9Y577    477   TRI17_HUMAN E3 ubiquitin-protein ligase TRIM1...260.044     40     54     65GO:0005622; C:intracellular; IEA:InterPro.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
242Q5D7I3    495   TRIM5_ERYPA Tripartite motif-containing prote...730.045     40     26     48GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
243Q9BYE7    350   PCGF6_HUMAN Polycomb group RING finger protei...480.045     39.7     40     48GO:0035102; C:PRC1 complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
244Q9WV59    477   TRI17_RAT E3 ubiquitin-protein ligase TRIM17 ...260.045     40     54     65GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
245Q8BGE7    488   TRIM6_MOUSE Tripartite motif-containing prote...650.046     40     31     52GO:0005737; C:cytoplasm; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
246Q28GL3    416   RNFT1_XENTR RING finger and transmembrane dom...390.046     39.7     44     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
247Q2XNS1    231   RN141_CANFA RING finger protein 141 OS=Canis ...420.047     39.3     36     52
GO:0008270; F:zinc ion binding; IEA:InterPro.
248Q6AZZ1    485   TRI68_HUMAN E3 ubiquitin-protein ligase TRIM6...710.048     39.7     30     45GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
249Q99MB7    230   RN141_MOUSE RING finger protein 141 OS=Mus mu...420.048     39.3     36     52
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IDA:MGI.
250Q9FIY7    1277   SM3L3_ARATH Putative SWI/SNF-related matrix-a...520.049     40     40     52GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
251Q6IV57    230   RN141_RAT RING finger protein 141 OS=Rattus n...420.05     38.9     36     52
GO:0008270; F:zinc ion binding; IEA:InterPro.
252E9Q555    5150   RN213_MOUSE E3 ubiquitin-protein ligase RNF21...400.05     40     45     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
253Q86WT6    500   TRI69_HUMAN Tripartite motif-containing prote...430.05     39.7     37     51GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
254O74563    680   BRL2_SCHPO E3 ubiquitin-protein ligase brl2 O...560.052     40     30     50GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.
255Q1XHT8    229   TRI40_PANTR Tripartite motif-containing prote...570.053     38.9     35     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
256Q6GQD5    314   RN146_XENLA E3 ubiquitin-protein ligase rnf14...540.053     39.3     37     43GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
257Q6CWM4    663   BRE1_KLULA E3 ubiquitin-protein ligase BRE1 O...480.053     39.7     33     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
258Q8WU17    664   RN139_HUMAN E3 ubiquitin-protein ligase RNF13...390.053     39.7     44     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0070613; P:regulation of protein processing; IDA:UniProtKB.::GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
259Q5A4X0    681   BRE1_CANAL E3 ubiquitin-protein ligase BRE1 O...480.053     39.7     35     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030447; P:filamentous growth; IMP:CGD.
260Q2YEM8    494   TRIM5_BUNHO Tripartite motif-containing prote...720.054     39.7     28     49GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
261Q62191    470   RO52_MOUSE E3 ubiquitin-protein ligase TRIM21...760.055     39.7     32     50GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
262Q5RBT7    664   RN139_PONAB E3 ubiquitin-protein ligase RNF13...390.056     39.7     44     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
263Q8IYW5    571   RN168_HUMAN E3 ubiquitin-protein ligase RNF16...520.057     39.7     37     50GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; IDA:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
264Q4WDD7    725   BRE1_ASPFU E3 ubiquitin-protein ligase bre1 O...450.057     39.7     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
265Q6NTV1    416   RNFT1_XENLA RING finger and transmembrane dom...380.057     39.7     39     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
266Q4U5R4    230   RN114_BOVIN RING finger protein 114 OS=Bos ta...390.06     38.9     41     59
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
267Q7SDY3    405   CWC24_NEUCR Pre-mRNA-splicing factor cwc-24 O...390.061     39.3     38     49GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
268Q7TMV1    668   RN139_MOUSE E3 ubiquitin-protein ligase RNF13...390.061     39.7     44     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031396; P:regulation of protein ubiquitination; ISS:UniProtKB.
269Q55G16    355   RN113_DICDI RING finger protein 113 homolog O...400.061     39.3     43     43
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
270Q9C037    500   TRIM4_HUMAN Tripartite motif-containing prote...650.064     39.3     32     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070206; P:protein trimerization; IDA:UniProtKB.
271Q4P400    355   CWC24_USTMA Pre-mRNA-splicing factor CWC24 OS...880.065     39.3     28     40GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
records
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