Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P35820    1601   PSC_DROME Polycomb group protein Psc OS=Droso...600.012     42     33     50GO:0005725; C:intercalary heterochromatin; NAS:FlyBase.::GO:0005704; C:polytene chromosome band; IDA:FlyBase.::GO:0035102; C:PRC1 complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006338; P:chromatin remodeling; IDA:FlyBase.::GO:0006342; P:chromatin silencing; IDA:FlyBase.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IMP:FlyBase.
182Q5AVC5    332   CWC24_EMENI Pre-mRNA-splicing factor cwc24 OS...460.012     41.6     37     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
183D2H0Y8    359   RN146_AILME E3 ubiquitin-protein ligase RNF14...870.013     41.6     31     40GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
184Q7ZWF4    685   RN145_DANRE RING finger protein 145 OS=Danio ...380.014     41.6     45     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
185Q9CWS1    417   RN135_MOUSE E3 ubiquitin-protein ligase RNF13...930.015     41.2     28     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0032728; P:positive regulation of interferon-beta production; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.
186Q495X7    471   TRI60_HUMAN Tripartite motif-containing prote...450.016     41.2     42     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
187Q96MT1    663   RN145_HUMAN RING finger protein 145 OS=Homo s...380.016     41.6     45     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
188Q05568    337   PEX10_YEAST Peroxisome biogenesis factor 10 O...390.016     41.2     38     54GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IMP:SGD.
189C0HBT3    349   RN146_SALSA E3 ubiquitin-protein ligase rnf14...540.017     41.2     37     43GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
190Q0IIM1    573   RN168_BOVIN E3 ubiquitin-protein ligase RNF16...520.017     41.2     38     48GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
191Q8C0E3    641   TRI47_MOUSE Tripartite motif-containing prote...700.017     41.6     34     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
192Q99NA9    353   PCGF6_MOUSE Polycomb group RING finger protei...480.017     40.8     40     48GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
193B2RYR0    564   RN168_RAT E3 ubiquitin-protein ligase RNF168 ...520.018     41.2     38     52GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
194Q6IV56    222   RN141_DANRE RING finger protein 141 OS=Danio ...630.018     40.4     33     46
GO:0008270; F:zinc ion binding; IEA:InterPro.
195Q810I2    483   TRI50_MOUSE E3 ubiquitin-protein ligase TRIM5...480.019     41.2     35     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
196Q9FKA7    617   ORTH1_ARATH E3 ubiquitin-protein ligase ORTHR...402.3     34.7     38     45GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; IDA:TAIR.::GO:0010428; F:methyl-CpNpG binding; IDA:TAIR.::GO:0010429; F:methyl-CpNpN binding; IDA:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:UniProtKB.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
197Q9D9R0    233   RN125_MOUSE E3 ubiquitin-protein ligase RNF12...400.019     40.4     48     58GO:0005829; C:cytosol; TAS:Reactome.
GO:0004842; F:ubiquitin-protein ligase activity; EXP:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
198O74757    677   HRD1_SCHPO ERAD-associated E3 ubiquitin-prote...1270.019     41.2     28     44GO:0005938; C:cell cortex; IDA:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IMP:PomBase.::GO:0010620; P:negative regulation of transcription by transcription factor catabolism; IMP:PomBase.
199Q96LD4    638   TRI47_HUMAN Tripartite motif-containing prote...700.019     41.2     34     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
200Q5SWK7    663   RN145_MOUSE RING finger protein 145 OS=Mus mu...380.02     41.2     45     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
201Q8GUK7    243   RMA3_ARATH E3 ubiquitin-protein ligase RMA3 O...480.021     40.4     42     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
202Q8VYZ0    645   ORTH2_ARATH E3 ubiquitin-protein ligase ORTHR...845.5     33.5     24     39GO:0010369; C:chromocenter; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:TAIR.::GO:0010385; F:double-stranded methylated DNA binding; IDA:TAIR.::GO:0042393; F:histone binding; IPI:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IDA:TAIR.::GO:0031508; P:centromeric heterochromatin assembly; IMP:TAIR.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:UniProtKB.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB.
203Q8K243    485   TRI68_MOUSE E3 ubiquitin-protein ligase TRIM6...650.021     40.8     34     48GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
204P84445    532   ICP0_EHV1V E3 ubiquitin-protein ligase ICP0 O...400.022     40.8     43     53
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
205P28990    532   ICP0_EHV1B E3 ubiquitin-protein ligase ICP0 O...400.022     40.8     43     53
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
206Q7ZYZ7    261   PCGF1_DANRE Polycomb group RING finger protei...520.022     40.4     33     52GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
207Q5XI70    351   PCGF6_RAT Polycomb group RING finger protein ...490.022     40.8     39     49GO:0035102; C:PRC1 complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
208Q2U9B0    760   BRE1_ASPOR E3 ubiquitin-protein ligase bre1 O...490.023     41.2     35     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
209Q9DCN7    395   RNFT1_MOUSE RING finger and transmembrane dom...380.023     40.8     45     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
210Q14258    630   TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 ...650.025     40.8     35     51GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
211Q6NZ21    419   RNFT1_DANRE RING finger and transmembrane dom...380.025     40.4     45     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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