Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR066W
Length:
487
Number of sequences:
5887
Description:
YCR066W RAD18 SGDID:S000000662, Chr III from 231500-232963, Genome Release 64-1-1, Verified ORF, "E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q91431    610   NF7O_XENLA Nuclear factor 7, ovary OS=Xenopus...750.005     43.1     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
152P39429    501   TRAF2_MOUSE TNF receptor-associated factor 2 ...490.006     42.7     37     59GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.
GO:0005174; F:CD40 receptor binding; IPI:BHF-UCL.::GO:0046625; F:sphingolipid binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; NAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0030163; P:protein catabolic process; IMP:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0051023; P:regulation of immunoglobulin secretion; IMP:MGI.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:UniProtKB.
153Q640S6    477   TRI72_XENTR Tripartite motif-containing prote...820.006     42.7     30     44GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
154Q99728    777   BARD1_HUMAN BRCA1-associated RING domain prot...800.006     42.7     34     50GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB.
155O64425    249   RMA1_ARATH E3 ubiquitin-protein ligase RMA1 O...640.007     42     38     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032527; P:protein exit from endoplasmic reticulum; IMP:TAIR.::GO:0032940; P:secretion by cell; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
156Q09463    235   RNF5_CAEEL RING finger protein 5 OS=Caenorhab...430.007     41.6     42     58GO:0030054; C:cell junction; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.::GO:0055002; P:striated muscle cell development; IMP:WormBase.
157Q810I1    483   TRI50_RAT E3 ubiquitin-protein ligase TRIM50 ...480.007     42.4     35     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
158Q6R567    252   RMA1_CAPAN E3 ubiquitin-protein ligase RMA1H1...580.007     42     36     47GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009723; P:response to ethylene stimulus; IEP:UniProtKB.::GO:0006970; P:response to osmotic stress; IEP:UniProtKB.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.::GO:0009611; P:response to wounding; IEP:UniProtKB.
159Q9ESN6    744   TRIM2_MOUSE Tripartite motif-containing prote...860.007     42.7     29     51GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0017022; F:myosin binding; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0043526; P:neuroprotection; IMP:UniProtKB.
160P70191    558   TRAF5_MOUSE TNF receptor-associated factor 5 ...460.008     42.4     43     54GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.
GO:0004871; F:signal transducer activity; IMP:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
161Q7YR33    465   TRI15_PANTR Tripartite motif-containing prote...580.008     42.4     38     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
162D3ZQG6    744   TRIM2_RAT Tripartite motif-containing protein...860.008     42.4     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; IMP:UniProtKB.
163Q9P6R8    533   CWC24_SCHPO Pre-mRNA-splicing factor cwf24 OS...430.008     42.4     40     44GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; TAS:PomBase.::GO:0016074; P:snoRNA metabolic process; NAS:PomBase.
164Q6PC78    194   RN185_DANRE E3 ubiquitin-protein ligase RNF18...460.009     41.2     41     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
165Q2KHN1    245   RN151_HUMAN RING finger protein 151 OS=Homo s...480.009     41.6     40     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
166Q336R3    844   BRE1B_ORYSJ E3 ubiquitin-protein ligase BRE1-...530.009     42.4     40     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
167A2ZAC2    844   BRE1B_ORYSI E3 ubiquitin-protein ligase BRE1-...530.009     42.4     40     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
168B3DK16    234   PCF5A_DANRE Polycomb group RING finger protei...680.009     41.2     34     49GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
169Q5D7J2    497   TRIM5_PAPAN Tripartite motif-containing prote...800.009     42     25     49GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
170E1B7X3    346   R146A_BOVIN E3 ubiquitin-protein ligase RNF14...740.009     42     34     45GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
171P31244    790   RAD16_YEAST DNA repair protein RAD16 OS=Sacch...440.01     42.4     36     57GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0000113; C:nucleotide-excision repair factor 4 complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.
172Q4QR06    259   PCGF1_XENLA Polycomb group RING finger protei...530.01     41.6     34     53GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
173Q28H21    259   PCGF1_XENTR Polycomb group RING finger protei...530.01     41.2     34     53GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
174B1AUE5    324   PEX10_MOUSE Peroxisome biogenesis factor 10 O...420.01     41.6     40     52GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
175Q1XHU0    518   TRI39_PANTR Tripartite motif-containing prote...410.011     42     41     54GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
176Q91187    1073   RAG1_ONCMY V(D)J recombination-activating pro...390.011     42.4     41     56GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
177Q9HCM9    518   TRI39_HUMAN Tripartite motif-containing prote...410.011     42     41     54GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
178Q6MFZ5    488   TRI39_RAT Tripartite motif-containing protein...410.011     42     41     54GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
179Q9C019    465   TRI15_HUMAN Tripartite motif-containing prote...580.011     42     38     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.
180Q9ESN2    488   TRI39_MOUSE Tripartite motif-containing prote...410.011     42     41     54GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
181P35820    1601   PSC_DROME Polycomb group protein Psc OS=Droso...600.012     42     33     50GO:0005725; C:intercalary heterochromatin; NAS:FlyBase.::GO:0005704; C:polytene chromosome band; IDA:FlyBase.::GO:0035102; C:PRC1 complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006338; P:chromatin remodeling; IDA:FlyBase.::GO:0006342; P:chromatin silencing; IDA:FlyBase.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IMP:FlyBase.
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