Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR065W
Length:
564
Number of sequences:
5887
Description:
YCR065W HCM1 SGDID:S000000661, Chr III from 229310-231004, Genome Release 64-1-1, Verified ORF, "Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q91904    370   FXI1A_XENLA Forkhead box protein I1-A OS=Xeno...1556e-20     95.1     37     55GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0048264; P:determination of ventral identity; IMP:UniProtKB.::GO:0007398; P:ectoderm development; IMP:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92Q91905    367   FXI1B_XENLA Forkhead box protein I1-B OS=Xeno...917e-20     95.1     48     66GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0048264; P:determination of ventral identity; IMP:UniProtKB.::GO:0007398; P:ectoderm development; IMP:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93Q3UCQ1    651   FOXK2_MOUSE Forkhead box protein K2 OS=Mus mu...1057e-20     97.1     48     60GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
94Q8AWH1    428   FOXA1_XENTR Forkhead box protein A1 OS=Xenopu...887e-20     95.9     51     64GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0010817; P:regulation of hormone levels; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
95Q60987    481   FOXG1_MOUSE Forkhead box protein G1 OS=Mus mu...897e-20     96.3     49     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0016199; P:axon midline choice point recognition; IMP:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0009792; P:embryo development ending in birth or egg hatching; IBA:RefGenome.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0030902; P:hindbrain development; IBA:RefGenome.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0035058; P:nonmotile primary cilium assembly; IBA:RefGenome.::GO:0043584; P:nose development; IBA:RefGenome.::GO:0045787; P:positive regulation of cell cycle; IMP:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007346; P:regulation of mitotic cell cycle; IMP:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
96Q00939    480   FOXG1_RAT Forkhead box protein G1 OS=Rattus n...898e-20     96.3     49     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0007568; P:aging; IEP:RGD.::GO:0016199; P:axon midline choice point recognition; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IBA:RefGenome.::GO:0030902; P:hindbrain development; IBA:RefGenome.::GO:0042472; P:inner ear morphogenesis; IBA:RefGenome.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0035058; P:nonmotile primary cilium assembly; IBA:RefGenome.::GO:0043584; P:nose development; IBA:RefGenome.::GO:0045787; P:positive regulation of cell cycle; IBA:RefGenome.::GO:0002052; P:positive regulation of neuroblast proliferation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
97P23512    466   FOXA1_RAT Hepatocyte nuclear factor 3-alpha O...889e-20     95.9     51     64GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IDA:RGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060743; P:epithelial cell maturation involved in prostate gland development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0060740; P:prostate gland epithelium morphogenesis; IBA:RefGenome.::GO:0060741; P:prostate gland stromal morphogenesis; IBA:RefGenome.::GO:0010817; P:regulation of hormone levels; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IBA:RefGenome.
98Q01167    660   FOXK2_HUMAN Forkhead box protein K2 OS=Homo s...1051e-19     96.7     48     60GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
99P55316    489   FOXG1_HUMAN Forkhead box protein G1 OS=Homo s...891e-19     95.9     49     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0016199; P:axon midline choice point recognition; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IBA:RefGenome.::GO:0030902; P:hindbrain development; IBA:RefGenome.::GO:0042472; P:inner ear morphogenesis; IBA:RefGenome.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035058; P:nonmotile primary cilium assembly; IBA:RefGenome.::GO:0043584; P:nose development; IBA:RefGenome.::GO:0045787; P:positive regulation of cell cycle; IBA:RefGenome.::GO:0002052; P:positive regulation of neuroblast proliferation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
100Q1A1A5    489   FOXG1_CERPY Forkhead box protein G1 OS=Cercop...891e-19     95.9     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
101Q1A1A3    485   FOXG1_EPOGA Forkhead box protein G1 OS=Epomop...891e-19     95.9     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q1A1A4    484   FOXG1_PIPRU Forkhead box protein G1 OS=Pipist...891e-19     95.9     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103Q1A1A6    489   FOXG1_CEBCA Forkhead box protein G1 OS=Cebus ...891e-19     95.9     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
104Q1A1A1    486   FOXG1_CERSI Forkhead box protein G1 OS=Cerato...891e-19     95.9     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105Q1A1A2    488   FOXG1_EQUBU Forkhead box protein G1 OS=Equus ...891e-19     95.9     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106Q61080    378   FOXF1_MOUSE Forkhead box protein F1 OS=Mus mu...891e-19     94.4     47     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0071345; P:cellular response to cytokine stimulus; IDA:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IMP:MGI.::GO:0014822; P:detection of wounding; IMP:MGI.::GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0048617; P:embryonic foregut morphogenesis; IMP:MGI.::GO:0061030; P:epithelial cell differentiation involved in mammary gland alveolus development; IGI:MGI.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IMP:MGI.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IGI:MGI.::GO:0030198; P:extracellular matrix organization; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0048371; P:lateral mesodermal cell differentiation; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0060463; P:lung lobe morphogenesis; IMP:MGI.::GO:0090131; P:mesenchyme migration; IMP:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043305; P:negative regulation of mast cell degranulation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0051150; P:regulation of smooth muscle cell differentiation; IMP:MGI.::GO:0060461; P:right lung morphogenesis; IMP:MGI.::GO:0051145; P:smooth muscle cell differentiation; IMP:MGI.::GO:0007224; P:smoothened signaling pathway; IDA:MGI.::GO:0001756; P:somitogenesis; IMP:MGI.::GO:0060438; P:trachea development; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.
107O93529    319   FOXB1_XENLA Forkhead box protein B1 OS=Xenopu...891e-19     93.6     51     62GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0007412; P:axon target recognition; ISS:UniProtKB.::GO:0061381; P:cell migration in diencephalon; ISS:UniProtKB.::GO:0007398; P:ectoderm development; IEP:UniProtKB.::GO:0033504; P:floor plate development; ISS:UniProtKB.::GO:0021855; P:hypothalamus cell migration; ISS:UniProtKB.::GO:0061379; P:inferior colliculus development; ISS:UniProtKB.::GO:0061374; P:mammillothalamic axonal tract development; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0001756; P:somitogenesis; ISS:UniProtKB.::GO:0022029; P:telencephalon cell migration; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008542; P:visual learning; ISS:UniProtKB.
108P33206    400   FXA4B_XENLA Forkhead box protein A4-B OS=Xeno...881e-19     94.7     50     65GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
109Q6P839    399   FOXA4_XENTR Forkhead box protein A4 OS=Xenopu...882e-19     94.4     49     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0010817; P:regulation of hormone levels; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
110P33205    399   FXA4A_XENLA Forkhead box protein A4-A OS=Xeno...882e-19     94     49     65GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030900; P:forebrain development; IMP:UniProtKB.::GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0001840; P:neural plate development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q12950    439   FOXD4_HUMAN Forkhead box protein D4 OS=Homo s...882e-19     94.4     52     66GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; ISS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.::GO:0051216; P:cartilage development; IBA:RefGenome.::GO:0060678; P:dichotomous subdivision of terminal units involved in ureteric bud branching; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048484; P:enteric nervous system development; IBA:RefGenome.::GO:0050935; P:iridophore differentiation; IBA:RefGenome.::GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.::GO:0030318; P:melanocyte differentiation; IBA:RefGenome.::GO:0001755; P:neural crest cell migration; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0030513; P:positive regulation of BMP signaling pathway; IBA:RefGenome.::GO:0090184; P:positive regulation of kidney development; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
112Q12946    379   FOXF1_HUMAN Forkhead box protein F1 OS=Homo s...892e-19     93.6     47     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0060446; P:branching involved in open tracheal system development; IMP:DFLAT.::GO:0003214; P:cardiac left ventricle morphogenesis; IMP:DFLAT.::GO:0048613; P:embryonic ectodermal digestive tract morphogenesis; IMP:DFLAT.::GO:0003197; P:endocardial cushion development; IMP:DFLAT.::GO:0001701; P:in utero embryonic development; IMP:DFLAT.::GO:0060426; P:lung vasculature development; IMP:DFLAT.::GO:0007494; P:midgut development; IMP:DFLAT.::GO:0031016; P:pancreas development; IMP:DFLAT.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0072189; P:ureter development; IMP:DFLAT.::GO:0060841; P:venous blood vessel development; IMP:DFLAT.
113Q7ZX03    642   FOXK2_XENLA Forkhead box protein K2 OS=Xenopu...1052e-19     95.5     48     60GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
114A1L1S5    380   FOXF1_DANRE Forkhead box protein F1 OS=Danio ...892e-19     93.6     47     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
115O00358    373   FOXE1_HUMAN Forkhead box protein E1 OS=Homo s...883e-19     93.2     49     63GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0048562; P:embryonic organ morphogenesis; ISS:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.::GO:0060022; P:hard palate development; IMP:UniProtKB.::GO:0002089; P:lens morphogenesis in camera-type eye; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0060465; P:pharynx development; IEP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060023; P:soft palate development; IMP:UniProtKB.::GO:0048538; P:thymus development; IEP:UniProtKB.::GO:0030878; P:thyroid gland development; IMP:UniProtKB.::GO:0006590; P:thyroid hormone generation; ISS:UniProtKB.
116Q9W707    372   FXF1B_XENLA Forkhead box protein F1-B OS=Xeno...1103e-19     93.2     40     60GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0030509; P:BMP signaling pathway; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0048566; P:embryonic digestive tract development; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048745; P:smooth muscle tissue development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117Q9W706    373   FXF1A_XENLA Forkhead box protein F1-A OS=Xeno...1103e-19     93.2     40     60GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0048566; P:embryonic digestive tract development; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048745; P:smooth muscle tissue development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118O54743    446   FOXF2_MOUSE Forkhead box protein F2 OS=Mus mu...893e-19     94     47     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048566; P:embryonic digestive tract development; IGI:MGI.::GO:0042249; P:establishment of planar polarity of embryonic epithelium; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
119P32182    458   FOXA2_RAT Hepatocyte nuclear factor 3-beta OS...884e-19     94     52     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0046332; F:SMAD binding; IDA:RGD.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0007596; P:blood coagulation; IBA:RefGenome.::GO:0021533; P:cell differentiation in hindbrain; IBA:RefGenome.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0021904; P:dorsal/ventral neural tube patterning; IBA:RefGenome.::GO:0001705; P:ectoderm formation; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; IBA:RefGenome.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0001701; P:in utero embryonic development; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0090009; P:primitive streak formation; ISS:UniProtKB.::GO:0032868; P:response to insulin stimulus; IEP:RGD.
120Q12947    444   FOXF2_HUMAN Forkhead box protein F2 OS=Homo s...894e-19     94     47     65GO:0005667; C:transcription factor complex; IDA:UniProtKB.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0001837; P:epithelial to mesenchymal transition; NAS:UniProtKB.::GO:0048806; P:genitalia development; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
121Q8JIT6    317   FOXB2_XENLA Forkhead box protein B2 OS=Xenopu...894e-19     92     51     61GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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