Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR065W
Length:
564
Number of sequences:
5887
Description:
YCR065W HCM1 SGDID:S000000661, Chr III from 229310-231004, Genome Release 64-1-1, Verified ORF, "Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q6VFT6    377   FOXL2_PIG Forkhead box protein L2 OS=Sus scro...902e-21     99.8     52     67GO:0005634; C:nucleus; ISS:AgBase.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:AgBase.
GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; ISS:AgBase.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; ISS:AgBase.::GO:0060014; P:granulosa cell differentiation; ISS:AgBase.::GO:0006917; P:induction of apoptosis; ISS:AgBase.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:AgBase.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32Q4VUF1    373   FOXL2_ELLLU Forkhead box protein L2 OS=Ellobi...902e-21     99.4     52     67GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33Q6VFT5    384   FOXL2_RABIT Forkhead box protein L2 OS=Orycto...903e-21     99.4     52     67GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34P32315    427   FXA1B_XENLA Forkhead box protein A1-B OS=Xeno...883e-21     100     53     65GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35Q63248    101   FOXI2_RAT Forkhead box protein I2 OS=Rattus n...883e-21     94     50     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009957; P:epidermal cell fate specification; IBA:RefGenome.::GO:0043049; P:otic placode formation; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
36P58012    376   FOXL2_HUMAN Forkhead box protein L2 OS=Homo s...903e-21     99.4     52     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IMP:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
GO:0060026; P:convergent extension; IBA:RefGenome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IMP:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.::GO:0002074; P:extraocular skeletal muscle development; IMP:UniProtKB.::GO:0019101; P:female somatic sex determination; IBA:RefGenome.::GO:0006917; P:induction of apoptosis; IBA:RefGenome.::GO:0042703; P:menstruation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
37Q6VFT7    377   FOXL2_BOVIN Forkhead box protein L2 OS=Bos ta...903e-21     99.4     52     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome.
GO:0060026; P:convergent extension; IBA:RefGenome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; ISS:AgBase.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; ISS:AgBase.::GO:0060014; P:granulosa cell differentiation; ISS:AgBase.::GO:0006917; P:induction of apoptosis; ISS:AgBase.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:AgBase.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
38Q6LD29    429   FXA1A_XENLA Forkhead box protein A1-A OS=Xeno...1273e-21     99.8     43     54GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
39Q07342    409   FOXA2_DANRE Forkhead box protein A2 OS=Danio ...883e-21     99.8     53     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
40Q8MIP2    377   FOXL2_CAPHI Forkhead box protein L2 OS=Capra ...903e-21     99.4     52     67GO:0005634; C:nucleus; ISS:AgBase.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; ISS:AgBase.::GO:0008210; P:estrogen metabolic process; NAS:UniProtKB.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; ISS:AgBase.::GO:0060014; P:granulosa cell differentiation; ISS:AgBase.::GO:0006917; P:induction of apoptosis; ISS:AgBase.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; IEP:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41Q91765    434   FXA2A_XENLA Forkhead box protein A2-A OS=Xeno...883e-21     99.8     53     65GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q9UJU5    478   FOXD3_HUMAN Forkhead box protein D3 OS=Homo s...883e-21     100     56     68GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.::GO:0051216; P:cartilage development; IBA:RefGenome.::GO:0001892; P:embryonic placenta development; IBA:RefGenome.::GO:0048484; P:enteric nervous system development; IBA:RefGenome.::GO:0050935; P:iridophore differentiation; IBA:RefGenome.::GO:0001822; P:kidney development; IBA:RefGenome.::GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.::GO:0030318; P:melanocyte differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.::GO:0001829; P:trophectodermal cell differentiation; IBA:RefGenome.
43Q7T1R4    434   FOXA2_XENTR Forkhead box protein A2 OS=Xenopu...883e-21     99.8     53     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009952; P:anterior/posterior pattern specification; IBA:RefGenome.::GO:0007596; P:blood coagulation; IBA:RefGenome.::GO:0021533; P:cell differentiation in hindbrain; IBA:RefGenome.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0021904; P:dorsal/ventral neural tube patterning; IBA:RefGenome.::GO:0001705; P:ectoderm formation; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; IBA:RefGenome.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0001707; P:mesoderm formation; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
44Q9DEN4    371   FXD3A_XENLA Forkhead box protein D3-A OS=Xeno...883e-21     99     55     68GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0050768; P:negative regulation of neurogenesis; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; IMP:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45Q6P2Z3    363   FOXI1_XENTR Forkhead box protein I1 OS=Xenopu...914e-21     99     49     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048264; P:determination of ventral identity; ISS:UniProtKB.::GO:0007398; P:ectoderm development; ISS:UniProtKB.::GO:0009957; P:epidermal cell fate specification; IBA:RefGenome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043049; P:otic placode formation; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
46Q6P8A3    373   FXI1E_XENTR Forkhead box protein I1-ema OS=Xe...975e-21     98.6     49     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009957; P:epidermal cell fate specification; IBA:RefGenome.::GO:0042664; P:negative regulation of endodermal cell fate specification; ISS:UniProtKB.::GO:0048335; P:negative regulation of mesodermal cell fate determination; ISS:UniProtKB.::GO:0043049; P:otic placode formation; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
47P55317    472   FOXA1_HUMAN Hepatocyte nuclear factor 3-alpha...885e-21     100     52     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060743; P:epithelial cell maturation involved in prostate gland development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0008634; P:negative regulation of survival gene product expression; IDA:UniProtKB.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IC:BHF-UCL.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0060740; P:prostate gland epithelium morphogenesis; IBA:RefGenome.::GO:0060741; P:prostate gland stromal morphogenesis; IBA:RefGenome.::GO:0032355; P:response to estradiol stimulus; IDA:UniProtKB.::GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IBA:RefGenome.
48P84961    433   FXA2B_XENLA Forkhead box protein A2-B OS=Xeno...885e-21     99.4     52     65GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0001707; P:mesoderm formation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49Q5J3Q5    379   FOXE1_XENLA Forkhead box protein E1 OS=Xenopu...1265e-21     98.6     42     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50Q7ZYQ0    373   FXI1E_XENLA Forkhead box protein I1-ema OS=Xe...975e-21     98.6     49     65GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042664; P:negative regulation of endodermal cell fate specification; IMP:UniProtKB.::GO:0048335; P:negative regulation of mesodermal cell fate determination; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51P35582    468   FOXA1_MOUSE Hepatocyte nuclear factor 3-alpha...886e-21     99.8     52     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0006338; P:chromatin remodeling; IDA:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060743; P:epithelial cell maturation involved in prostate gland development; IMP:MGI.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IGI:MGI.::GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IGI:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0042445; P:hormone metabolic process; IMP:MGI.::GO:0060487; P:lung epithelial cell differentiation; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0048665; P:neuron fate specification; IGI:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060740; P:prostate gland epithelium morphogenesis; IMP:MGI.::GO:0060741; P:prostate gland stromal morphogenesis; IMP:MGI.::GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IMP:MGI.
52Q12951    378   FOXI1_HUMAN Forkhead box protein I1 OS=Homo s...976e-21     98.2     49     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; NAS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0009957; P:epidermal cell fate specification; IBA:RefGenome.::GO:0043049; P:otic placode formation; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
53Q6ZQN5    318   FOXI2_HUMAN Forkhead box protein I2 OS=Homo s...886e-21     97.4     52     67GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009957; P:epidermal cell fate specification; IBA:RefGenome.::GO:0043049; P:otic placode formation; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
54P85037    733   FOXK1_HUMAN Forkhead box protein K1 OS=Homo s...1026e-21     100     50     61GO:0005730; C:nucleolus; IDA:HPA.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0000287; F:magnesium ion binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
55Q90WN4    346   FOXD2_XENLA Forkhead box protein D2 OS=Xenopu...887e-21     97.8     52     68GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56P32183    354   FOXA3_RAT Hepatocyte nuclear factor 3-gamma O...887e-21     97.8     51     65GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0007420; P:brain development; IBA:RefGenome.::GO:0001678; P:cellular glucose homeostasis; TAS:UniProtKB.::GO:0009267; P:cellular response to starvation; IBA:RefGenome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0021999; P:neural plate anterior/posterior regionalization; IBA:RefGenome.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0070368; P:positive regulation of hepatocyte differentiation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
57Q9Y261    457   FOXA2_HUMAN Hepatocyte nuclear factor 3-beta ...887e-21     99.4     53     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0021533; P:cell differentiation in hindbrain; IBA:RefGenome.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0021904; P:dorsal/ventral neural tube patterning; IBA:RefGenome.::GO:0001705; P:ectoderm formation; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; IDA:BHF-UCL.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0001701; P:in utero embryonic development; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:2000971; P:negative regulation of detection of glucose; ISS:BHF-UCL.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0033132; P:negative regulation of glucokinase activity; ISS:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; ISS:BHF-UCL.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IC:BHF-UCL.::GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; ISS:BHF-UCL.::GO:0090009; P:primitive streak formation; ISS:UniProtKB.::GO:0030193; P:regulation of blood coagulation; IDA:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:BHF-UCL.::GO:2000976; P:regulation of transcription from RNA polymerase II promoter involved in detection of glucose; ISS:BHF-UCL.::GO:0070741; P:response to interleukin-6; TAS:UniProtKB.
58P35583    459   FOXA2_MOUSE Hepatocyte nuclear factor 3-beta ...887e-21     99.4     53     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0007596; P:blood coagulation; IBA:RefGenome.::GO:0021533; P:cell differentiation in hindbrain; IMP:MGI.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0021904; P:dorsal/ventral neural tube patterning; IDA:MGI.::GO:0001705; P:ectoderm formation; IGI:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0060487; P:lung epithelial cell differentiation; IGI:MGI.::GO:2000971; P:negative regulation of detection of glucose; IDA:BHF-UCL.::GO:0033132; P:negative regulation of glucokinase activity; IDA:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IGI:MGI.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IDA:BHF-UCL.::GO:0048665; P:neuron fate specification; IMP:MGI.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:0040019; P:positive regulation of embryonic development; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IDA:BHF-UCL.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0090009; P:primitive streak formation; IMP:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:BHF-UCL.::GO:2000976; P:regulation of transcription from RNA polymerase II promoter involved in detection of glucose; IDA:BHF-UCL.::GO:0070741; P:response to interleukin-6; TAS:UniProtKB.::GO:0023019; P:signal transduction involved in regulation of gene expression; IDA:MGI.::GO:0032525; P:somite rostral/caudal axis specification; IMP:MGI.
59P32030    322   SLP1_DROME Fork head domain transcription fac...1057e-21     97.4     49     62GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0008595; P:anterior/posterior axis specification, embryo; NAS:FlyBase.::GO:0016199; P:axon midline choice point recognition; IBA:RefGenome.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IBA:RefGenome.::GO:0060914; P:heart formation; IMP:FlyBase.::GO:0001707; P:mesoderm formation; TAS:FlyBase.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0035058; P:nonmotile primary cilium assembly; IBA:RefGenome.::GO:0007366; P:periodic partitioning by pair rule gene; IEA:UniProtKB-KW.::GO:0045787; P:positive regulation of cell cycle; IBA:RefGenome.::GO:0002052; P:positive regulation of neuroblast proliferation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0007380; P:specification of segmental identity, head; IMP:FlyBase.
60Q8BUR3    623   FOXJ3_MOUSE Forkhead box protein J3 OS=Mus mu...1727e-21     100     35     55GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
61Q6F2E4    329   FOXD1_XENTR Forkhead box protein D1 OS=Xenopu...887e-21     97.4     53     68GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.::GO:0051216; P:cartilage development; IBA:RefGenome.::GO:0060678; P:dichotomous subdivision of terminal units involved in ureteric bud branching; IBA:RefGenome.::GO:0007398; P:ectoderm development; ISS:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048484; P:enteric nervous system development; IBA:RefGenome.::GO:0030900; P:forebrain development; ISS:UniProtKB.::GO:0050935; P:iridophore differentiation; IBA:RefGenome.::GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.::GO:0030318; P:melanocyte differentiation; IBA:RefGenome.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0030513; P:positive regulation of BMP signaling pathway; IBA:RefGenome.::GO:0090184; P:positive regulation of kidney development; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
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