Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR065W
Length:
564
Number of sequences:
5887
Description:
YCR065W HCM1 SGDID:S000000661, Chr III from 229310-231004, Genome Release 64-1-1, Verified ORF, "Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P40466    484   FKH1_YEAST Fork head protein homolog 1 OS=Sac...920.00000000000001     80.5     42     59GO:0000790; C:nuclear chromatin; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0019237; F:centromeric DNA binding; IDA:SGD.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0071406; P:cellular response to methylmercury; IMP:SGD.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007535; P:donor selection; IMP:SGD.::GO:0007005; P:mitochondrion organization; IBA:RefGenome.::GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:2000221; P:negative regulation of pseudohyphal growth; IGI:SGD.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0060277; P:negative regulation of transcription involved in G1 phase of mitotic cell cycle; IGI:SGD.::GO:0090419; P:negative regulation of transcription involved in G2/M-phase of mitotic cell cycle; IMP:SGD.::GO:0090055; P:positive regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0090282; P:positive regulation of transcription involved in G2/M-phase of mitotic cell cycle; IGI:SGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006369; P:termination of RNA polymerase II transcription; IMP:SGD.
182Q28F43    334   FOXN2_XENTR Forkhead box protein N2 OS=Xenopu...820.00000000000002     78.2     46     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
183Q4VYS1    706   FOXP2_XENLA Forkhead box protein P2 OS=Xenopu...750.00000000000002     80.1     44     71GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
184P58463    714   FOXP2_MOUSE Forkhead box protein P2 OS=Mus mu...750.00000000000002     80.1     44     71GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IGI:MGI.::GO:0040007; P:growth; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IGI:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IMP:MGI.::GO:0007519; P:skeletal muscle tissue development; IGI:MGI.::GO:0048745; P:smooth muscle tissue development; IGI:MGI.::GO:0042297; P:vocal learning; IMP:MGI.
185Q5QL03    713   FOXP2_HYLLA Forkhead box protein P2 OS=Hyloba...750.00000000000002     80.1     44     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
186Q8MJ99    713   FOXP2_GORGO Forkhead box protein P2 OS=Gorill...750.00000000000002     80.1     44     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
187Q8MJ97    714   FOXP2_MACMU Forkhead box protein P2 OS=Macaca...750.00000000000002     80.1     44     71GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome.
188Q8MJA0    716   FOXP2_PANTR Forkhead box protein P2 OS=Pan tr...750.00000000000002     80.1     44     71GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome.
189Q8HZ00    716   FOXP2_PANPA Forkhead box protein P2 OS=Pan pa...750.00000000000002     80.1     44     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
190P0CF24    710   FOXP2_RAT Forkhead box protein P2 OS=Rattus n...750.00000000000002     80.1     44     71GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; IBA:RefGenome.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome.
191O15409    715   FOXP2_HUMAN Forkhead box protein P2 OS=Homo s...750.00000000000002     80.1     44     71GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; IMP:UniProtKB.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IEP:BHF-UCL.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; IMP:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome.
192Q8MJ98    713   FOXP2_PONPY Forkhead box protein P2 OS=Pongo ...750.00000000000002     80.1     44     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
193Q5W1J5    578   FOXP1_XENLA Forkhead box protein P1 OS=Xenopu...750.00000000000002     79.7     44     71GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
194Q4VYR7    641   FOXP4_XENLA Forkhead box protein P4 OS=Xenopu...750.00000000000003     79.3     43     72GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
195Q66J77    430   FOXN2_XENLA Forkhead box protein N2 OS=Xenopu...820.00000000000003     78.6     46     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
196Q6EUW1    657   FOXO3_XENLA Forkhead box protein O3 OS=Xenopu...790.00000000000003     79.3     47     61GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
197O14270    743   FHL1_SCHPO Fork head transcription factor 1 O...960.00000000000004     79.3     41     57GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; TAS:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
198Q8K3Q3    521   FOXN4_MOUSE Forkhead box protein N4 OS=Mus mu...1170.00000000000004     78.6     37     53GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048675; P:axon extension; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048663; P:neuron fate commitment; IGI:MGI.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IBA:RefGenome.::GO:0008016; P:regulation of heart contraction; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
199Q96NZ1    517   FOXN4_HUMAN Forkhead box protein N4 OS=Homo s...1170.00000000000004     78.6     37     53GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048675; P:axon extension; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0008016; P:regulation of heart contraction; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
200Q8IVH2    680   FOXP4_HUMAN Forkhead box protein P4 OS=Homo s...750.00000000000004     79     43     72GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048617; P:embryonic foregut morphogenesis; IBA:RefGenome.::GO:0007507; P:heart development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
201Q9DBY0    795   FOXP4_MOUSE Forkhead box protein P4 OS=Mus mu...750.00000000000007     78.6     43     72GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048617; P:embryonic foregut morphogenesis; IMP:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
202Q810W5    653   FOXO1_SPETR Forkhead box protein O1 OS=(Ictid...1050.00000000000009     77.8     43     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
203Q9R1E0    652   FOXO1_MOUSE Forkhead box protein O1 OS=Mus mu...950.00000000000009     77.8     45     55GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0001568; P:blood vessel development; IMP:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
204Q12778    655   FOXO1_HUMAN Forkhead box protein O1 OS=Homo s...950.0000000000001     77.4     45     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
205Q3BJS1    506   FOXN4_XENLA Forkhead box protein N4 OS=Xenopu...1170.0000000000001     77     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
206Q61575    648   FOXN1_MOUSE Forkhead box protein N1 OS=Mus mu...830.0000000000001     77.4     46     61GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0050673; P:epithelial cell proliferation; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IDA:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0033081; P:regulation of T cell differentiation in thymus; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI.
207O15353    648   FOXN1_HUMAN Forkhead box protein N1 OS=Homo s...830.0000000000001     77     46     61GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0006952; P:defense response; TAS:ProtInc.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0050673; P:epithelial cell proliferation; IBA:RefGenome.::GO:0030216; P:keratinocyte differentiation; IBA:RefGenome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048538; P:thymus development; IBA:RefGenome.
208O16850    541   FOXO_CAEEL Forkhead box protein O OS=Caenorha...810.0000000000001     77     43     63GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0034605; P:cellular response to heat; IDA:UniProtKB.::GO:0008340; P:determination of adult lifespan; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060537; P:muscle tissue development; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:UniProtKB.::GO:0002821; P:positive regulation of adaptive immune response; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IEP:UniProtKB.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; IMP:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0046890; P:regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
209P98177    505   FOXO4_HUMAN Forkhead box protein O4 OS=Homo s...780.0000000000002     76.6     47     59GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
210Q9I9E1    472   FOXH1_DANRE Forkhead box protein H1 OS=Danio ...1190.0000000000002     76.3     38     54GO:0032444; C:activin responsive factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0070412; F:R-SMAD binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:ZFIN.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048327; P:axial mesodermal cell fate specification; IMP:ZFIN.::GO:0001568; P:blood vessel development; IMP:ZFIN.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:ZFIN.::GO:0042074; P:cell migration involved in gastrulation; IMP:ZFIN.::GO:0009953; P:dorsal/ventral pattern formation; IMP:ZFIN.::GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IBA:RefGenome.::GO:0060971; P:embryonic heart tube left/right pattern formation; IMP:ZFIN.::GO:0001706; P:endoderm formation; IMP:ZFIN.::GO:0021508; P:floor plate formation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:ZFIN.::GO:0014028; P:notochord formation; IMP:ZFIN.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0021501; P:prechordal plate formation; IMP:ZFIN.::GO:2000223; P:regulation of BMP signaling pathway involved in heart jogging; IMP:ZFIN.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0032525; P:somite rostral/caudal axis specification; IMP:ZFIN.::GO:0010159; P:specification of organ position; IMP:ZFIN.::GO:0060063; P:Spemann organizer formation at the embryonic shield; IMP:ZFIN.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
211Q9WVH3    505   FOXO4_MOUSE Forkhead box protein O4 OS=Mus mu...780.0000000000002     76.3     47     59GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000080; P:G1 phase of mitotic cell cycle; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IDA:MGI.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
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