UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YCR057C

Length:

923

Number of sequences:

5887

Description:

YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
751	Q9VU68	608	WDR1_DROME Actin-interacting protein 1 OS=Dro...	223	0.26	38.9	22	37	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.
									GO:0003779; F:actin binding; ISS:FlyBase.
									GO:0030042; P:actin filament depolymerization; IMP:FlyBase.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB.::GO:0035317; P:imaginal disc-derived wing hair organization; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0030834; P:regulation of actin filament depolymerization; IMP:UniProtKB.::GO:0045214; P:sarcomere organization; IMP:FlyBase.
752	A2QCU8	670	SCONB_ASPNC Probable E3 ubiquitin ligase comp...	217	0.0001	49.3	24	39
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
753	A1CH75	488	YTM1_ASPCL Ribosome biogenesis protein ytm1 O...	260	0.000004	54.3	23	40	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
754	O16519	620	GAD1_CAEEL Gastrulation defective protein 1 O...	84	0.56	37.7	32	50
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0042074; P:cell migration involved in gastrulation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:WormBase.
755	Q4P8R5	814	MDV1_USTMA Mitochondrial division protein 1 O...	34	2.2	35.8	38	65	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
756	A1CXL0	488	YTM1_NEOFI Ribosome biogenesis protein ytm1 O...	202	0.037	41.2	24	38	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
757	Q3SZD4	432	WDR18_BOVIN WD repeat-containing protein 18 O...	63	3	35	30	51
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
758	A6ZZZ8	645	CAF4_YEAS7 CCR4-associated factor 4 OS=Saccha...	299	0.000004	54.3	21	41	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
759	Q2GSJ9	1080	HIR1_CHAGB Protein HIR1 OS=6347 / NRRL 1970) ...	397	0.012	43.1	22	35	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
760	P53197	566	CDH1_YEAST APC/C activator protein CDH1 OS=Sa...	241	0.000004	54.3	22	44	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0030332; F:cyclin binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
									GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010697; P:negative regulation of spindle pole body separation; IMP:SGD.::GO:2000600; P:positive regulation of cyclin catabolic process; IDA:SGD.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.
761	Q5RHI5	647	DTL_DANRE Denticleless protein homolog OS=Dan...	161	5.7	34.3	21	45	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:ZFIN.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
762	Q9QZD9	325	EIF3I_MOUSE Eukaryotic translation initiation...	101	4.2	34.3	24	42	GO:0005852; C:eukaryotic translation initiation factor 3 complex; IDA:UniProtKB.
									GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
763	P36130	643	CAF4_YEAST CCR4-associated factor 4 OS=Saccha...	299	0.000005	54.3	21	41	GO:0030014; C:CCR4-NOT complex; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
									GO:0000266; P:mitochondrial fission; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:SGD.
764	Q8C6G8	641	WDR26_MOUSE WD repeat-containing protein 26 O...	319	0.0006	47.4	20	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
765	A5D7H2	797	STRN3_BOVIN Striatin-3 OS=Bos taurus (Bovine)...	274	0.012	43.1	20	38	GO:0005654; C:nucleoplasm; ISS:UniProtKB.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
766	P59328	1117	WDHD1_MOUSE WD repeat and HMG-box DNA-binding...	274	1.7	36.2	21	38	GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
767	B4MY77	335	CIAO1_DROWI Probable cytosolic iron-sulfur pr...	196	0.41	37.7	21	40
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
768	Q5EBE8	325	EIF3I_XENTR Eukaryotic translation initiation...	170	1.1	36.2	22	47	GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
									GO:0003743; F:translation initiation factor activity; ISS:UniProtKB.
769	B0BNA7	325	EIF3I_RAT Eukaryotic translation initiation f...	101	4.5	34.3	24	42	GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
									GO:0003743; F:translation initiation factor activity; ISS:UniProtKB.
770	Q4VBE8	431	WDR18_MOUSE WD repeat-containing protein 18 O...	41	0.86	37	37	61
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
771	Q06440	651	CORO_YEAST Coronin-like protein OS=Saccharomy...	144	0.000006	53.9	26	46	GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005826; C:actomyosin contractile ring; IBA:RefGenome.
									GO:0051015; F:actin filament binding; IDA:SGD.::GO:0008017; F:microtubule binding; IDA:SGD.::GO:0030674; F:protein binding, bridging; IDA:SGD.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0007015; P:actin filament organization; IMP:SGD.::GO:0007017; P:microtubule-based process; IPI:SGD.::GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; IDA:SGD.::GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IDA:SGD.
772	Q9CX97	388	WDR55_MOUSE WD repeat-containing protein 55 O...	160	0.033	41.2	24	46	GO:0005737; C:cytoplasm; IMP:UniProtKB.::GO:0005730; C:nucleolus; IMP:UniProtKB.
									GO:0006364; P:rRNA processing; IMP:UniProtKB.
773	B7QKS1	315	CIAO1_IXOSC Probable cytosolic iron-sulfur pr...	84	0.54	37.4	29	50
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
774	Q5E966	325	EIF3I_BOVIN Eukaryotic translation initiation...	101	4	34.7	24	42	GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
									GO:0003743; F:translation initiation factor activity; ISS:UniProtKB.
775	A8PTE4	674	MDV1_MALGO Mitochondrial division protein 1 O...	149	0.00003	51.6	26	44	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
776	Q5AZX0	567	PFS2_EMENI Polyadenylation factor subunit 2 O...	240	6.2	34.3	20	35	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
777	C5DF48	457	LIS1_LACTC Nuclear distribution protein PAC1 ...	120	0.072	40.4	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
778	B4P7Q3	335	CIAO1_DROYA Probable cytosolic iron-sulfur pr...	245	0.54	37.4	20	37
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
779	A6ZYM0	330	CIAO1_YEAS7 Probable cytosolic iron-sulfur pr...	119	0.9	36.6	25	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
780	B3NQR5	335	CIAO1_DROER Probable cytosolic iron-sulfur pr...	245	0.53	37.4	20	37
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
781	Q8R537	318	PEX7_CRIGR Peroxisomal targeting signal 2 rec...	158	5.2	34.3	24	41	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0005053; F:peroxisome matrix targeting signal-2 binding; ISS:UniProtKB.
									GO:0008611; P:ether lipid biosynthetic process; ISS:UniProtKB.::GO:0016558; P:protein import into peroxisome matrix; ISS:UniProtKB.

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