Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR057C
Length:
923
Number of sequences:
5887
Description:
YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601O75037    1637   KI21B_HUMAN Kinesin-like protein KIF21B OS=Ho...3400.17     39.7     19     38GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
602Q5BDU4    1031   HIR1_EMENI Protein hir1 OS=194 / M139) (Asper...3820.00007     50.4     19     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
603A2AHJ4    1799   BRWD3_MOUSE Bromodomain and WD repeat-contain...3440.005     44.7     23     36
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
604Q20059    683   WDR48_CAEEL WD repeat-containing protein 48 h...1410.009     43.5     20     43
605Q9BRP4    392   PAAF1_HUMAN Proteasomal ATPase-associated fac...800.37     38.1     28     43GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
606Q9QXL1    1668   KI21B_MOUSE Kinesin-like protein KIF21B OS=Mu...2130.042     41.6     20     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
607P27612    794   PLAP_MOUSE Phospholipase A-2-activating prote...1730.038     41.6     20     39
GO:0016005; F:phospholipase A2 activator activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006954; P:inflammatory response; IDA:MGI.
608Q01277    650   SCONB_NEUCR Probable E3 ubiquitin ligase comp...990.002     45.8     34     52
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
609B0XFT7    328   EIF3I_CULQU Eukaryotic translation initiation...1394     34.7     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
610O76071    339   CIAO1_HUMAN Probable cytosolic iron-sulfur pr...1710.16     38.9     20     41GO:0071817; C:MMXD complex; IDA:UniProtKB.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; IGI:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
611Q21215    325   GBLP_CAEEL Guanine nucleotide-binding protein...1460.002     45.1     23     41GO:0030424; C:axon; IDA:WormBase.::GO:0044297; C:cell body; IDA:WormBase.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0030426; C:growth cone; IDA:WormBase.::GO:0000776; C:kinetochore; IDA:WormBase.::GO:0005635; C:nuclear envelope; IDA:WormBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0048675; P:axon extension; IMP:WormBase.::GO:0051304; P:chromosome separation; IMP:WormBase.::GO:0000281; P:cytokinesis after mitosis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0008045; P:motor axon guidance; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006997; P:nucleus organization; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0033365; P:protein localization to organelle; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IMP:WormBase.
612O14170    703   POP2_SCHPO WD repeat-containing protein pop2 ...1780.0001     49.7     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:PomBase.
613B4NW98    322   EIF3I_DROYA Eukaryotic translation initiation...2460.98     36.6     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
614Q5RAC9    607   A16L1_PONAB Autophagy-related protein 16-1 OS...583.2     35     29     53GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
615O14053    902   YC47_SCHPO Uncharacterized WD repeat-containi...1070.008     43.9     23     46GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; NAS:PomBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.::GO:0032040; C:small-subunit processome; IEA:InterPro.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0006364; P:rRNA processing; ISS:PomBase.
616Q54R82    942   MKKA_DICDI Mitogen-activated protein kinase k...3200.0000007     57     23     37GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
617Q9NSI6    2320   BRWD1_HUMAN Bromodomain and WD repeat-contain...769.4     33.9     25     47GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
618Q54S59    299   WDR61_DICDI WD repeat-containing protein 61 h...2570.00000008     58.5     21     44
619P0CS46    712   PFS2_CRYNJ Polyadenylation factor subunit 2 O...3180.00002     52.4     20     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
620A3LNM0    525   IPI3_PICST Pre-rRNA-processing protein IPI3 O...2770.00001     52.8     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
621Q62440    770   TLE1_MOUSE Transducin-like enhancer protein 1...1420.81     37.4     20     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
622Q04724    770   TLE1_HUMAN Transducin-like enhancer protein 1...1420.86     37     19     45
GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
623P0CS47    713   PFS2_CRYNB Polyadenylation factor subunit 2 O...3180.00001     52.4     20     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
624Q06078    939   UTP21_YEAST U3 small nucleolar RNA-associated...2860.025     42     21     42GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0042274; P:ribosomal small subunit biogenesis; IC:SGD.::GO:0006364; P:rRNA processing; IGI:SGD.
625Q5ACW8    853   HIR1_CANAL Protein HIR1 OS=Candida albicans (...3240.000009     53.5     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
626O13286    556   SRW1_SCHPO WD repeat-containing protein srw1 ...3311.7     35.8     20     37GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IC:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.
627O02482    612   UNC37_CAEEL Transcription factor unc-37 OS=Ca...1860.14     39.7     21     41GO:0005634; C:nucleus; IDA:WormBase.
GO:0008134; F:transcription factor binding; IPI:WormBase.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0050770; P:regulation of axonogenesis; IMP:WormBase.::GO:0001505; P:regulation of neurotransmitter levels; IDA:WormBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
628Q32PJ6    339   CIAO1_BOVIN Probable cytosolic iron-sulfur pr...1710.13     39.3     20     41GO:0071817; C:MMXD complex; ISS:UniProtKB.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
629Q93134    316   GBLP_BIOGL Guanine nucleotide-binding protein...1410.038     40.8     27     44
630P36037    715   DOA1_YEAST Protein DOA1 OS=Saccharomyces cere...1230.009     43.5     31     46GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
631P53196    417   RPN14_YEAST 26S proteasome regulatory subunit...830.53     37.4     25     43GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
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