Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR057C
Length:
923
Number of sequences:
5887
Description:
YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q12834    499   CDC20_HUMAN Cell division cycle protein 20 ho...2370.000000003     64.3     22     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
512Q6CB13    565   MDV1_YARLI Mitochondrial division protein 1 O...1720.000001     55.8     29     43GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
513Q54SF9    941   MHCKD_DICDI Myosin heavy chain kinase D OS=Di...2390.00002     52.4     22     45
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; ISS:dictyBase.
GO:0031037; P:myosin II filament disassembly; IMP:dictyBase.
514Q0U2T3    681   MDV1_PHANO Mitochondrial division protein 1 O...2980.00000004     60.8     24     42GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
515Q55FJ2    766   WDR91_DICDI WD repeat-containing protein 91 h...1010.074     40.4     26     50
516Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...2030.31     38.5     21     44
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
517Q6CSI1    408   HAT2_KLULA Histone acetyltransferase type B s...2000.000000003     63.5     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
518Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...680.8     37     32     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
519Q09731    962   BU107_SCHPO UBP9-binding protein bun107 OS=Sc...1910.03     42     23     42GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:2000158; P:positive regulation of ubiquitin-specific protease activity; IMP:PomBase.
520A7RWD2    327   CIAO1_NEMVE Probable cytosolic iron-sulfur pr...1412.1     35.4     23     42
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
521Q2UFN8    705   SCONB_ASPOR Probable E3 ubiquitin ligase comp...1070.005     44.3     28     51
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
522B8NGT5    706   SCONB_ASPFN Probable E3 ubiquitin ligase comp...1070.004     44.7     28     51
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
523P49177    377   GBB_ARATH Guanine nucleotide-binding protein ...780.11     39.7     31     53GO:0080008; C:CUL4 RING ubiquitin ligase complex; IPI:TAIR.::GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005834; C:heterotrimeric G-protein complex; IPI:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:TAIR.::GO:0010154; P:fruit development; IMP:TAIR.::GO:0009867; P:jasmonic acid mediated signaling pathway; IMP:TAIR.::GO:0048527; P:lateral root development; IMP:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:UniProtKB.::GO:0009887; P:organ morphogenesis; IMP:TAIR.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0009723; P:response to ethylene stimulus; IMP:TAIR.::GO:0009845; P:seed germination; IEP:UniProtKB.
524Q0UNC6    1044   HIR1_PHANO Protein HIR1 OS=(Glume blotch fung...2480.0002     49.3     24     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
525Q9UKT8    454   FBXW2_HUMAN F-box/WD repeat-containing protei...690.006     43.9     33     52
GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
GO:0006508; P:proteolysis; TAS:ProtInc.
526Q58D00    454   FBXW2_BOVIN F-box/WD repeat-containing protei...690.007     43.5     33     52
527C4JZS6    446   LIS11_UNCRE Nuclear distribution protein PAC1...1820.0007     47     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
528Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...2720.000002     55.5     25     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
529Q5H7C0    499   CDC20_PIG Cell division cycle protein 20 homo...2370.000000005     63.5     22     43GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
530Q7Z4S6    1674   KI21A_HUMAN Kinesin-like protein KIF21A OS=Ho...2180.6     37.7     20     38GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
531P16649    713   TUP1_YEAST General transcriptional corepresso...1830.0001     49.3     26     43GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
532B4JB43    326   EIF3I_DROGR Eukaryotic translation initiation...1170.18     38.9     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
533Q4P5F5    455   CIAO1_USTMA Probable cytosolic iron-sulfur pr...2420.36     38.1     24     40
534Q9JHB4    367   WDR31_MOUSE WD repeat-containing protein 31 O...1022.1     35.4     19     53
535B4LUA5    322   EIF3I_DROVI Eukaryotic translation initiation...2480.71     37     20     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
536Q4V7A0    305   WDR61_RAT WD repeat-containing protein 61 OS=...1910.002     45.1     27     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
537Q9ERF3    305   WDR61_MOUSE WD repeat-containing protein 61 O...1910.002     45.1     27     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
538Q32LN7    305   WDR61_BOVIN WD repeat-containing protein 61 O...1910.001     45.8     27     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
539Q9GZS3    305   WDR61_HUMAN WD repeat-containing protein 61 O...1910.001     45.8     27     42GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.::GO:0055087; C:Ski complex; IDA:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
540C5FP68    674   SCONB_ARTOC Probable E3 ubiquitin ligase comp...720.23     38.9     35     47
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
541Q54PP7    1154   LVSF_DICDI BEACH domain-containing protein lv...2120.051     41.2     21     39
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