Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR057C
Length:
923
Number of sequences:
5887
Description:
YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481Q5ZMV7    313   WDR82_CHICK WD repeat-containing protein 82 O...2800.049     40.4     22     35GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
482Q55DA2    333   CIAO1_DICDI Probable cytosolic iron-sulfur pr...3380.00000007     58.9     23     41
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
483O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...2680.000000007     63.2     22     43GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
484A4RJV3    661   MDV1_MAGO7 Mitochondrial division protein 1 O...1116.6     34.3     24     47GO:0030015; C:CCR4-NOT core complex; ISS:PAMGO_MGG.::GO:0005741; C:mitochondrial outer membrane; ISS:PAMGO_MGG.
GO:0051020; F:GTPase binding; ISS:PAMGO_MGG.
GO:0000266; P:mitochondrial fission; ISS:PAMGO_MGG.::GO:0000002; P:mitochondrial genome maintenance; ISS:PAMGO_MGG.::GO:0006402; P:mRNA catabolic process; ISS:PAMGO_MGG.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:PAMGO_MGG.::GO:0006354; P:transcription elongation, DNA-dependent; ISS:PAMGO_MGG.::GO:0006352; P:transcription initiation, DNA-dependent; ISS:PAMGO_MGG.
485Q6NV31    313   WDR82_DANRE WD repeat-containing protein 82 O...1900.012     42.4     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
486P87053    605   POF1_SCHPO F-box/WD repeat-containing protein...822.6     35.4     30     55GO:0000152; C:nuclear ubiquitin ligase complex; ISS:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0071276; P:cellular response to cadmium ion; IEP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IPI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
487Q8SQS4    556   TAF5_ENCCU Transcription initiation factor TF...1232.2     35.8     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
488P73595    334   Y1410_SYNY3 Uncharacterized WD repeat-contain...1310.58     37.4     24     46GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB.
489P87060    775   POP1_SCHPO WD repeat-containing protein pop1 ...2640.075     40.4     21     38GO:0005634; C:nucleus; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0006995; P:cellular response to nitrogen starvation; IGI:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
490B4KGX9    322   EIF3I_DROMO Eukaryotic translation initiation...1000.37     37.7     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
491P93397    377   GBB1_TOBAC Guanine nucleotide-binding protein...770.04     41.2     32     51
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
492Q6TNS2    368   PK1IP_DANRE p21-activated protein kinase-inte...2574.6     34.3     20     40GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
493P93339    377   GBB_NICPL Guanine nucleotide-binding protein ...770.059     40.4     32     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
494O94394    369   YQF1_SCHPO Uncharacterized WD repeat-containi...1750.000001     55.5     28     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
495Q40507    375   GBB3_TOBAC Guanine nucleotide-binding protein...770.084     40     31     51
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
496Q9BQ87    522   TBL1Y_HUMAN F-box-like/WD repeat-containing p...2670.00000002     62     21     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
497Q09150    302   REC14_SCHPO Meiotic recombination protein rec...2820.000003     53.9     22     39GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0055087; C:Ski complex; ISS:PomBase.
GO:0006402; P:mRNA catabolic process; ISS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
498Q4P4R3    1017   HIR1_USTMA Protein HIR1 OS=Ustilago maydis (s...3780.073     40.8     22     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
499A1C7E4    700   SCONB_ASPCL Probable E3 ubiquitin ligase comp...1070.002     45.4     29     51
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
500P40968    455   PRP17_YEAST Pre-mRNA-processing factor 17 OS=...3020.000000001     65.1     23     39GO:0005681; C:spliceosomal complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IMP:SGD.::GO:0000389; P:nuclear mRNA 3'-splice site recognition; IGI:SGD.::GO:0000348; P:nuclear mRNA branch site recognition; IGI:SGD.
501B2RZ17    454   FBXW2_RAT F-box/WD repeat-containing protein ...650.005     44.3     35     54
502Q5I0B9    622   ATG16_XENTR Autophagy-related protein 16 OS=X...1380.056     40.8     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
503Q60584    422   FBXW2_MOUSE F-box/WD repeat-containing protei...690.002     45.1     35     52GO:0005737; C:cytoplasm; IDA:MGI.
504Q758R7    715   MDV1_ASHGO Mitochondrial division protein 1 O...1280.076     40.4     24     45GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
505O74184    314   WAT1_SCHPO WD repeat-containing protein wat1 ...1850.008     43.1     24     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006397; P:mRNA processing; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
506Q0D0X6    446   LIS1_ASPTN Nuclear distribution protein nudF ...680.39     38.1     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
507Q26544    301   WSL17_SCHMA WD repeat-containing protein SL1-...1700.33     37.7     22     41
508Q5ZJH5    305   WDR61_CHICK WD repeat-containing protein 61 O...1910.002     45.1     27     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
509Q8CGF6    920   WDR47_MOUSE WD repeat-containing protein 47 O...3290.00002     52     22     38
510Q0CY32    673   SCONB_ASPTN Probable E3 ubiquitin ligase comp...1070.004     44.7     29     51
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
511Q12834    499   CDC20_HUMAN Cell division cycle protein 20 ho...2370.000000003     64.3     22     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
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