Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR057C
Length:
923
Number of sequences:
5887
Description:
YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421P63243    317   GBLP_BOVIN Guanine nucleotide-binding protein...2540.033     41.2     19     39GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
422Q9UNX4    943   WDR3_HUMAN WD repeat-containing protein 3 OS=...1497.1     34.3     26     46GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
423Q9W5Z5    427   WSB1_TAKRU WD repeat and SOCS box-containing ...1840.011     42.7     22     40
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
424Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...2540.007     43.9     21     44GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
425P87314    932   HIR1_SCHPO Protein hir1 OS=Schizosaccharomyce...1320.003     45.4     25     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0000417; C:HIR complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; TAS:PomBase.
GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
426A1CBP8    655   MDV1_ASPCL Mitochondrial division protein 1 O...570.56     37.7     30     54GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
427Q5F3D7    520   UTP15_CHICK U3 small nucleolar RNA-associated...832.2     35.4     25     45GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
428Q58E77    313   WD82B_XENLA WD repeat-containing protein 82-B...1670.013     42.4     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
429Q640J6    313   WD82A_XENLA WD repeat-containing protein 82-A...2990.02     41.6     22     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
430Q6FJS0    455   PFS2_CANGA Polyadenylation factor subunit 2 O...2070.0005     47.4     25     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
431B0XAF3    338   CIAO1_CULQU Probable cytosolic iron-sulfur pr...3411.2     36.2     21     35
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
432Q5ZMC3    476   WSDU1_CHICK WD repeat, SAM and U-box domain-c...1250.87     37     29     38GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
433Q8C4J7    801   TBL3_MOUSE Transducin beta-like protein 3 OS=...1930.048     41.2     21     40GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0032040; C:small-subunit processome; IEA:InterPro.
GO:0006364; P:rRNA processing; IEA:InterPro.
434Q8WWQ0    1821   PHIP_HUMAN PH-interacting protein OS=Homo sap...4310.0002     48.9     21     35GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005158; F:insulin receptor binding; NAS:UniProtKB.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; NAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
435Q6FT96    711   MDV1_CANGA Mitochondrial division protein 1 O...3240.018     42.4     22     37GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
436Q0V8J1    406   WSB2_BOVIN WD repeat and SOCS box-containing ...1200.015     42.4     27     47
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
437P93398    377   GBB2_TOBAC Guanine nucleotide-binding protein...770.04     41.2     32     51
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
438Q9VU65    391   POC1_DROME POC1 centriolar protein homolog OS...1735.5     34.3     17     43
GO:0051297; P:centrosome organization; IMP:FlyBase.
439O43815    780   STRN_HUMAN Striatin OS=Homo sapiens (Human). ...3911.3     36.6     19     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; ISS:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB.
GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0070830; P:tight junction assembly; NAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IMP:UniProtKB.
440A1DDL6    658   MDV1_NEOFI Mitochondrial division protein 1 O...3870.015     42.7     20     37GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
441Q8N1V2    620   WDR16_HUMAN WD repeat-containing protein 16 O...2790.00001     52.4     18     37GO:0005737; C:cytoplasm; IDA:HPA.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.
442O54929    404   WSB2_MOUSE WD repeat and SOCS box-containing ...1200.008     43.5     27     48
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
443Q5REE0    518   UTP15_PONAB U3 small nucleolar RNA-associated...1013.2     35     25     45GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
444A7ETB3    667   MDV1_SCLS1 Mitochondrial division protein 1 O...1880.000001     55.8     26     43GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
445Q8VDD9    1821   PHIP_MOUSE PH-interacting protein OS=Mus musc...4310.0002     49.3     22     35GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045840; P:positive regulation of mitosis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; IDA:UniProtKB.
446Q9D0I6    474   WSDU1_MOUSE WD repeat, SAM and U-box domain-c...828.1     33.9     28     54GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
447A5DNK9    451   IPI3_PICGU Pre-rRNA-processing protein IPI3 O...2611.3     36.2     21     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
448Q4WVS4    658   MDV1_ASPFU Mitochondrial division protein 1 O...3840.03     41.6     20     36GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
449Q25189    317   GBLP_HYDVU Guanine nucleotide-binding protein...1390.000009     52.4     25     43
450Q3KQ62    314   WDR83_XENLA WD repeat domain-containing prote...2440.00002     51.2     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
451Q5XGE2    515   UTP15_XENTR U3 small nucleolar RNA-associated...780.92     37     28     49GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
records
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