Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR057C
Length:
923
Number of sequences:
5887
Description:
YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q54Y96    530   SMU1_DICDI WD40 repeat-containing protein smu...2760.00000004     60.8     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
362A2QP30    443   LIS1_ASPNC Nuclear distribution protein nudF ...2811.6     36.2     19     37GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
363Q6ZMY6    472   WDR88_HUMAN WD repeat-containing protein 88 O...1421     36.6     23     44
364B2B766    468   LIS12_PODAN Nuclear distribution protein PAC1...1560.008     43.5     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
365Q5U2W5    800   TBL3_RAT Transducin beta-like protein 3 OS=Ra...2150.001     46.6     22     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0032040; C:small-subunit processome; IEA:InterPro.
GO:0006364; P:rRNA processing; IEA:InterPro.
366O42248    317   GBLP_DANRE Guanine nucleotide-binding protein...2630.047     40.4     19     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
367A0AUS0    487   WSDU1_DANRE WD repeat, SAM and U-box domain-c...1690.002     45.1     22     46GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
368A7MB12    519   UTP15_BOVIN U3 small nucleolar RNA-associated...1424     34.7     22     42GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
369P07834    779   CDC4_YEAST Cell division control protein 4 OS...2032.3     35.8     21     39GO:0016363; C:nuclear matrix; IDA:SGD.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
370Q9BRX9    315   WDR83_HUMAN WD repeat domain-containing prote...3600.014     42.4     19     36GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.
371P25382    515   NLE1_YEAST Ribosome assembly protein 4 OS=Sac...3870.0000003     58.2     21     37GO:0005730; C:nucleolus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
372Q7SZM9    519   TB1RA_XENLA F-box-like/WD repeat-containing p...3260.01     43.1     19     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
373Q9BZK7    514   TBL1R_HUMAN F-box-like/WD repeat-containing p...3260.009     43.5     19     36GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
374Q6GPC6    522   TB1RB_XENLA F-box-like/WD repeat-containing p...3260.011     43.1     19     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
375Q6L4F8    336   GBLPB_ORYSJ Guanine nucleotide-binding protei...1776.1     33.9     18     38
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
376Q8BHJ5    514   TBL1R_MOUSE F-box-like/WD repeat-containing p...3260.011     43.1     19     36
GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
377Q54LT8    293   STRAP_DICDI Serine-threonine kinase receptor-...2210.0006     46.6     24     43
GO:0004872; F:receptor activity; ISS:dictyBase.
GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:dictyBase.
378Q9UTC7    462   YIDC_SCHPO Uncharacterized WD repeat-containi...2149.7     33.5     19     37GO:0005829; C:cytosol; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
379O43071    558   PRP17_SCHPO Pre-mRNA-processing factor 17 OS=...1553     35     26     45GO:0005681; C:spliceosomal complex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
380Q01369    316   GBLP_NEUCR Guanine nucleotide-binding protein...1420.025     41.6     23     42
381Q54D08    304   LST8_DICDI Protein LST8 homolog OS=Dictyostel...1480.093     39.7     23     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
382Q8TED0    518   UTP15_HUMAN U3 small nucleolar RNA-associated...1446.9     33.9     23     42GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
383Q05946    817   UTP13_YEAST U3 small nucleolar RNA-associated...980.076     40.4     29     49GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
384Q6DH44    315   WDR83_DANRE WD repeat domain-containing prote...3170.0005     46.6     20     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
385P14197    478   AAC3_DICDI WD repeat-containing protein AAC3 ...1520.00004     50.8     22     42
386Q5F201    620   WDR16_MOUSE WD repeat-containing protein 16 O...784.7     34.7     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
387P38129    798   TAF5_YEAST Transcription initiation factor TF...2280.92     37     22     40GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.::GO:0005669; C:transcription factor TFIID complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032947; F:protein complex scaffold; IMP:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IC:SGD.
388Q0CJD8    654   MDV1_ASPTN Mitochondrial division protein 1 O...3550.0005     47.4     22     38GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
389Q09855    506   POF11_SCHPO F-box/WD repeat-containing protei...2250.089     40     20     40GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
390Q40687    380   GBB_ORYSJ Guanine nucleotide-binding protein ...870.001     45.8     33     53
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; IEP:Gramene.
391Q2U5Z8    650   MDV1_ASPOR Mitochondrial division protein 1 O...570.13     39.7     32     54GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
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