Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR057C
Length:
923
Number of sequences:
5887
Description:
YCR057C PWP2 SGDID:S000000653, Chr III from 223228-220457, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q7ZUV2    694   KTNB1_DANRE Katanin p80 WD40-containing subun...2260.038     41.6     21     40GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
32Q498M4    334   WDR5_RAT WD repeat-containing protein 5 OS=Ra...2010.39     37.7     25     40GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33P61965    334   WDR5_MOUSE WD repeat-containing protein 5 OS=...2010.39     37.7     25     40GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34P61964    334   WDR5_HUMAN WD repeat-containing protein 5 OS=...2010.39     37.7     25     40GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35Q2KIG2    334   WDR5_BOVIN WD repeat-containing protein 5 OS=...2010.41     37.7     25     40GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36Q3Y8L7    446   WDR69_CHLRE Outer row dynein assembly protein...2810.91     37     17     35GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
37P93107    606   PF20_CHLRE Flagellar WD repeat-containing pro...3300.000002     55.5     20     38GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.
38A0DB19    403   LIS11_PARTE Lissencephaly-1 homolog 1 OS=Para...2080.00000003     60.8     24     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
39Q10051    492   PRP19_CAEEL Pre-mRNA-processing factor 19 hom...2049.5     33.5     22     36GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
40Q9USN3    777   UTP13_SCHPO Probable U3 small nucleolar RNA-a...1790.00000001     62.4     24     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.::GO:0032040; C:small-subunit processome; IEA:InterPro.
GO:0030515; F:snoRNA binding; ISS:PomBase.
GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.
41Q5JTN6    314   WDR38_HUMAN WD repeat-containing protein 38 O...2030.014     42.4     23     40
42A0CH87    403   LIS12_PARTE Lissencephaly-1 homolog 2 OS=Para...1710.00000008     59.3     23     47GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
43Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...2290.34     38.1     22     40
44Q90ZL4    410   LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus...3430.000000002     64.3     20     37GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
45D3TLL6    411   LIS1_GLOMM Lissencephaly-1 homolog OS=Glossin...3250.000004     53.9     20     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
46Q6NZH4    410   LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus...3430.000000002     64.3     20     37GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
47Q17963    376   TG125_CAEEL WD repeat-containing protein tag-...3220.00000000002     70.1     23     42GO:0005634; C:nucleus; IDA:WormBase.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
48Q9D994    303   WDR38_MOUSE WD repeat-containing protein 38 O...1770.00003     50.4     25     43
49Q8H0T9    837   KTNB1_ARATH Katanin p80 WD40 repeat-containin...2030.18     39.3     21     38GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.
50Q5M786    334   WDR5_XENTR WD repeat-containing protein 5 OS=...2040.00001     52.4     22     46GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q5RE95    330   WDR5B_PONAB WD repeat-containing protein 5B O...2290.23     38.5     22     40
52D3BUN1    417   LIS1_POLPA Lissencephaly-1 homolog OS=Polysph...3690.00000000003     70.1     20     38GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
53P0CS42    433   LIS1_CRYNJ Nuclear distribution protein PAC1 ...3920.0000001     59.3     21     36GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
54P0CS43    433   LIS1_CRYNB Nuclear distribution protein PAC1 ...3920.0000001     59.3     21     36GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
55Q5IS43    410   LIS1_PANTR Platelet-activating factor acetylh...3430.0000003     57.8     19     37GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
56P63004    410   LIS1_RAT Platelet-activating factor acetylhyd...3430.00000004     60.5     19     37GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005871; C:kinesin complex; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0042598; C:vesicular fraction; IDA:RGD.
GO:0045505; F:dynein intermediate chain binding; IDA:RGD.::GO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD.
GO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD.::GO:0051660; P:establishment of centrosome localization; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0001764; P:neuron migration; IMP:RGD.::GO:0007097; P:nuclear migration; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0017145; P:stem cell division; IMP:RGD.
57P63005    410   LIS1_MOUSE Platelet-activating factor acetylh...3430.00000004     60.5     19     37GO:0005813; C:centrosome; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0051219; F:phosphoprotein binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.
GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007405; P:neuroblast proliferation; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0051081; P:nuclear envelope disassembly; IMP:MGI.::GO:0032319; P:regulation of Rho GTPase activity; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IDA:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.
58B0LSW3    410   LIS1_FELCA Platelet-activating factor acetylh...3430.00000004     60.5     19     37GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
59Q803D2    410   LIS1B_DANRE Lissencephaly-1 homolog B OS=Dani...3520.000002     55.1     20     38GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0045176; P:apical protein localization; IMP:ZFIN.::GO:0048854; P:brain morphogenesis; IMP:ZFIN.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0040023; P:establishment of nucleus localization; IMP:ZFIN.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045494; P:photoreceptor cell maintenance; IMP:ZFIN.::GO:0006810; P:transport; IEA:UniProtKB-KW.
60P43034    410   LIS1_HUMAN Platelet-activating factor acetylh...3430.00000004     60.1     19     37GO:0000235; C:astral microtubule; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0031512; C:motile primary cilium; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0034452; F:dynactin binding; ISS:BHF-UCL.::GO:0008201; F:heparin binding; ISS:BHF-UCL.::GO:0008017; F:microtubule binding; ISS:BHF-UCL.::GO:0043274; F:phospholipase binding; ISS:BHF-UCL.::GO:0051219; F:phosphoprotein binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
GO:0001675; P:acrosome assembly; ISS:BHF-UCL.::GO:0030036; P:actin cytoskeleton organization; ISS:BHF-UCL.::GO:0008344; P:adult locomotory behavior; IMP:BHF-UCL.::GO:0048854; P:brain morphogenesis; IMP:BHF-UCL.::GO:0021540; P:corpus callosum morphogenesis; IMP:BHF-UCL.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0021766; P:hippocampus development; ISS:BHF-UCL.::GO:0021819; P:layer formation in cerebral cortex; ISS:BHF-UCL.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:0001764; P:neuron migration; IMP:UniProtKB.::GO:0046469; P:platelet activating factor metabolic process; ISS:BHF-UCL.::GO:0032319; P:regulation of Rho GTPase activity; ISS:BHF-UCL.::GO:0008090; P:retrograde axon cargo transport; ISS:BHF-UCL.::GO:0007268; P:synaptic transmission; ISS:BHF-UCL.::GO:0047496; P:vesicle transport along microtubule; ISS:BHF-UCL.
61P43033    410   LIS1_BOVIN Platelet-activating factor acetylh...3430.00000006     59.7     19     37GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0034452; F:dynactin binding; IDA:BHF-UCL.::GO:0045502; F:dynein binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0008017; F:microtubule binding; IDA:MGI.::GO:0043274; F:phospholipase binding; IDA:BHF-UCL.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046469; P:platelet activating factor metabolic process; IDA:BHF-UCL.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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