Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR051W
Length:
222
Number of sequences:
5887
Description:
YCR051W YCR051W SGDID:S000000647, Chr III from 214071-214739, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q2IBE6    1663   CTTB2_PONAB Cortactin-binding protein 2 OS=Po...1300.00006     47     28     53
62P42773    168   CDN2C_HUMAN Cyclin-dependent kinase 4 inhibit...810.00008     45.1     33     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
63Q9QZH2    768   BARD1_RAT BRCA1-associated RING domain protei...1070.00008     46.6     27     50GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:RGD.
64Q2QL82    1647   CTTB2_MICMU Cortactin-binding protein 2 OS=Mi...1360.0001     46.6     29     49
65Q9BXW6    950   OSBL1_HUMAN Oxysterol-binding protein-related...1070.0001     46.2     32     48GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005543; F:phospholipid binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
66Q7Z020    1296   TRPA1_DROME Transient receptor potential cati...690.87     34.3     29     46GO:0016021; C:integral to membrane; IC:UniProtKB.
GO:0005261; F:cation channel activity; IDA:UniProtKB.
GO:0034605; P:cellular response to heat; IDA:FlyBase.::GO:0042745; P:circadian sleep/wake cycle; IMP:FlyBase.::GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IMP:FlyBase.::GO:0007613; P:memory; IMP:FlyBase.::GO:0043052; P:thermotaxis; IDA:FlyBase.
67Q4V890    654   FEM1A_RAT Protein fem-1 homolog A OS=Rattus n...1150.0001     46.2     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.
68Q8N8V4    417   ANS4B_HUMAN Ankyrin repeat and SAM domain-con...1150.17     36.2     29     47
69Q60773    166   CDN2D_MOUSE Cyclin-dependent kinase 4 inhibit...520.0001     44.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
70B1AK53    854   ESPN_HUMAN Espin OS=Homo sapiens (Human). GN=...411.8     33.1     41     56GO:0005903; C:brush border; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; ISS:UniProtKB.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
71Q9Z2G1    654   FM1AA_MOUSE Protein fem-1 homolog A-A OS=Mus ...1150.0001     45.8     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.
72Q5EA33    238   ANR49_BOVIN Ankyrin repeat domain-containing ...820.0002     45.1     34     55
73P57044    451   ILK_CAVPO Integrin-linked protein kinase OS=C...730.0002     45.4     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
74Q9Z2X2    231   PSD10_MOUSE 26S proteasome non-ATPase regulat...720.18     35.8     31     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
75Q13418    452   ILK_HUMAN Integrin-linked protein kinase OS=H...730.0002     45.4     34     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
76Q3SWY2    452   ILK_BOVIN Integrin-linked protein kinase OS=B...730.0002     45.4     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009966; P:regulation of signal transduction; IEA:InterPro.
77Q1RI12    694   Y921_RICBR Putative ankyrin repeat protein RB...1130.0002     45.4     28     50
78Q99J82    452   ILK_RAT Integrin-linked protein kinase OS=Rat...730.0002     45.4     34     56GO:0005911; C:cell-cell junction; IDA:RGD.::GO:0043034; C:costamere; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IDA:RGD.
GO:0007569; P:cell aging; IMP:RGD.::GO:0007050; P:cell cycle arrest; IMP:RGD.::GO:0043206; P:fibril organization; IMP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; IMP:RGD.::GO:0032288; P:myelin assembly; IMP:RGD.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:RGD.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:RGD.
79O55222    452   ILK_MOUSE Integrin-linked protein kinase OS=M...730.0002     45.4     34     56GO:0005925; C:focal adhesion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:MGI.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
80Q5R5V4    452   ILK_PONAB Integrin-linked protein kinase OS=P...730.0002     45.4     34     56GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009966; P:regulation of signal transduction; IEA:InterPro.
81Q6TGW5    214   OSTF1_DANRE Osteoclast-stimulating factor 1 O...691.2     33.1     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
82F8W2M1    904   HACE1_DANRE E3 ubiquitin-protein ligase HACE1...650.0002     45.4     35     55GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
83Q9Z2X3    231   PSD10_RAT 26S proteasome non-ATPase regulator...721.9     32.7     29     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
84A9JR78    1427   TONSL_DANRE Tonsoku-like protein OS=Danio rer...1100.0002     45.4     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043596; C:nuclear replication fork; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.
GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0031297; P:replication fork processing; ISS:UniProtKB.
85Q9DAM9    344   FANK1_MOUSE Fibronectin type 3 and ankyrin re...1330.0002     45.1     30     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
86Q09YJ3    1642   CTTB2_MUNMU Cortactin-binding protein 2 OS=Mu...1360.0002     45.4     29     49
87Q09YI1    1641   CTTB2_SHEEP Cortactin-binding protein 2 OS=Ov...1140.0002     45.4     29     50
88Q60772    168   CDN2C_MOUSE Cyclin-dependent kinase 4 inhibit...810.0002     43.9     30     51
GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.
89Q2IBF8    1653   CTTB2_EULMM Cortactin-binding protein 2 OS=Eu...1140.0002     45.4     29     50
90P53066    181   YGZ2_YEAST Ankyrin repeat-containing protein ...1340.0002     43.9     31     46
91A2VDR2    282   ACBD6_BOVIN Acyl-CoA-binding domain-containin...1060.0002     44.7     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
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