rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A0M8S4 | 1663 | CTTB2_PAPAN Cortactin-binding protein 2 OS=Pa... | 149 | 0.00001 | 49.3 | 28 | 51 | | | | | | | | | | | | | | | | | | | | | | 32 | Q2QLF8 | 1662 | CTTB2_CALJA Cortactin-binding protein 2 OS=Ca... | 130 | 0.00001 | 49.3 | 28 | 53 | | | | | | | | | | | | | | | | | | | | | | 33 | Q495M9 | 461 | USH1G_HUMAN Usher syndrome type-1G protein OS... | 75 | 0.00001 | 48.9 | 41 | 56 | GO:0015629; C:actin cytoskeleton; ISS:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0050957; P:equilibrioception; IMP:HGNC.::GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.::GO:0007605; P:sensory perception of sound; IMP:HGNC. | 34 | Q80T11 | 461 | USH1G_MOUSE Usher syndrome type-1G protein ho... | 75 | 0.00001 | 48.5 | 41 | 56 | GO:0015629; C:actin cytoskeleton; IDA:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060113; P:inner ear receptor cell differentiation; IMP:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI. | 35 | F1N6G5 | 909 | HACE1_BOVIN E3 ubiquitin-protein ligase HACE1... | 109 | 0.00002 | 48.9 | 30 | 54 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 36 | Q8IYU2 | 909 | HACE1_HUMAN E3 ubiquitin-protein ligase HACE1... | 109 | 0.00002 | 48.9 | 30 | 54 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016601; P:Rac protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 37 | O60237 | 982 | MYPT2_HUMAN Protein phosphatase 1 regulatory ... | 84 | 0.0006 | 43.9 | 30 | 61 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0008047; F:enzyme activator activity; TAS:ProtInc. | | | | | | | | | | GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 38 | Q6DCL5 | 944 | HACE1_XENLA E3 ubiquitin-protein ligase HACE1... | 164 | 0.00002 | 48.5 | 27 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 39 | Q28BK1 | 912 | HACE1_XENTR E3 ubiquitin-protein ligase HACE1... | 164 | 0.00002 | 48.5 | 27 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 40 | Q15327 | 319 | ANKR1_HUMAN Ankyrin repeat domain-containing ... | 109 | 0.00002 | 48.1 | 34 | 50 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0031674; C:I band; ISS:BHF-UCL. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.::GO:0003714; F:transcription corepressor activity; TAS:BHF-UCL. | | | | | | | | | | GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071347; P:cellular response to interleukin-1; IDA:BHF-UCL.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.::GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.::GO:0035994; P:response to muscle stretch; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; NAS:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 41 | Q0P5G1 | 1374 | TONSL_BOVIN Tonsoku-like protein OS=Bos tauru... | 107 | 0.00002 | 48.5 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0031297; P:replication fork processing; ISS:UniProtKB. | 42 | D3ZBM7 | 909 | HACE1_RAT E3 ubiquitin-protein ligase HACE1 O... | 109 | 0.00002 | 48.5 | 30 | 54 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | Q3U0D9 | 909 | HACE1_MOUSE E3 ubiquitin-protein ligase HACE1... | 109 | 0.00002 | 48.1 | 30 | 54 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | Q07E15 | 1645 | CTTB2_MUSPF Cortactin-binding protein 2 OS=Mu... | 135 | 0.00003 | 48.1 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 45 | Q86YT6 | 1006 | MIB1_HUMAN E3 ubiquitin-protein ligase MIB1 O... | 71 | 7.5 | 31.2 | 30 | 49 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; TAS:Reactome. | 46 | Q3V0J4 | 497 | ANR53_MOUSE Ankyrin repeat domain-containing ... | 161 | 0.00003 | 47.8 | 28 | 42 | | | | | | | | | | | | | | | | | | | | | | 47 | O75832 | 226 | PSD10_HUMAN 26S proteasome non-ATPase regulat... | 72 | 0.073 | 37 | 31 | 57 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 48 | Q9J4Z4 | 592 | V246_FOWPN Putative ankyrin repeat protein FP... | 101 | 0.001 | 43.1 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 49 | E1C656 | 942 | HACE1_CHICK E3 ubiquitin-protein ligase HACE1... | 70 | 0.00003 | 48.1 | 37 | 64 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 50 | Q80SY4 | 1006 | MIB1_MOUSE E3 ubiquitin-protein ligase MIB1 O... | 71 | 8 | 31.2 | 30 | 49 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001568; P:blood vessel development; IMP:MGI.::GO:0001947; P:heart looping; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0001841; P:neural tube formation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IMP:MGI.::GO:0045807; P:positive regulation of endocytosis; IDA:MGI.::GO:0001756; P:somitogenesis; IMP:MGI. | 51 | Q2QLA2 | 1665 | CTTB2_HORSE Cortactin-binding protein 2 OS=Eq... | 135 | 0.00003 | 48.1 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 52 | Q8WZ74 | 1663 | CTTB2_HUMAN Cortactin-binding protein 2 OS=Ho... | 129 | 0.00003 | 48.1 | 28 | 52 | | | | | | | | | | | | | | | | | | | | | | 53 | Q2IBF7 | 1663 | CTTB2_GORGO Cortactin-binding protein 2 OS=Go... | 129 | 0.00003 | 48.1 | 28 | 52 | | | | | | | | | | | | | | | | | | | | | | 54 | Q29RM5 | 653 | FEM1A_BOVIN Protein fem-1 homolog A OS=Bos ta... | 112 | 0.009 | 40.4 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB. | 55 | Q09YG9 | 1659 | CTTB2_SAIBB Cortactin-binding protein 2 OS=Sa... | 129 | 0.00003 | 47.8 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 56 | Q07DV1 | 1649 | CTTB2_AOTNA Cortactin-binding protein 2 OS=Ao... | 129 | 0.00003 | 47.8 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 57 | Q9BSK4 | 669 | FEM1A_HUMAN Protein fem-1 homolog A OS=Homo s... | 112 | 0.005 | 41.2 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031867; F:EP4 subtype prostaglandin E2 receptor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.::GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB. | 58 | Q2QLB3 | 1663 | CTTB2_CALMO Cortactin-binding protein 2 OS=Ca... | 129 | 0.00004 | 47.8 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 59 | Q9CR42 | 319 | ANKR1_MOUSE Ankyrin repeat domain-containing ... | 108 | 0.00004 | 47 | 31 | 48 | GO:0031674; C:I band; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0031432; F:titin binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB. | 60 | Q07DX4 | 1663 | CTTB2_NOMLE Cortactin-binding protein 2 OS=le... | 127 | 0.00005 | 47.4 | 28 | 51 | | | | | | | | | | | | | | | | | | | | | | 61 | Q2IBE6 | 1663 | CTTB2_PONAB Cortactin-binding protein 2 OS=Po... | 130 | 0.00006 | 47 | 28 | 53 | | | | | | | | | | | | | | | | | | | | | |