Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YCR038C
Length:
642
Number of sequences:
5887
Description:
YCR038C BUD5 SGDID:S000000634, Chr III from 199549-197621, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P25300    642   BUD5_YEAST Bud site selection protein 5 OS=Sa...6420     1321     100     100GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; TAS:SGD.
GO:0007120; P:axial cellular bud site selection; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0007124; P:pseudohyphal growth; TAS:SGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
2P25593    260   YCG8_YEAST Putative uncharacterized protein Y...2600     532     99     100GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
3Q8SSQ3    929   GEFM_DICDI Ras guanine nucleotide exchange fa...2094e-17     89.4     28     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0045762; P:positive regulation of adenylate cyclase activity; IMP:dictyBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
4Q8IS20    1457   GEFC_DICDI Ras guanine nucleotide exchange fa...2180.00000000000005     79.7     32     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
5P26674    911   STE6_SCHPO Protein ste6 OS=Schizosaccharomyce...2810.0000000000002     77.4     28     46GO:0005829; C:cytosol; IDA:PomBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
6Q92565    580   RPGF5_HUMAN Rap guanine nucleotide exchange f...2310.0000000000006     75.5     28     46GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
7P28818    1244   RGRF1_RAT Ras-specific guanine nucleotide-rel...2260.000000000001     75.5     27     46GO:0005829; C:cytosol; ISS:HGNC.::GO:0030426; C:growth cone; ISS:HGNC.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; TAS:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0032863; P:activation of Rac GTPase activity; ISS:HGNC.::GO:0031175; P:neuron projection development; ISS:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0035020; P:regulation of Rac protein signal transduction; ISS:HGNC.::GO:0048167; P:regulation of synaptic plasticity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
8Q9USU1    987   EFC25_SCHPO Ras guanine nucleotide exchange f...2090.000000000005     72.8     28     51GO:0005829; C:cytosol; IDA:PomBase.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IMP:PomBase.
GO:0032488; P:Cdc42 protein signal transduction; TAS:PomBase.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
9P83900    580   RPGF5_RAT Rap guanine nucleotide exchange fac...2280.00000000001     71.2     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
10Q8C0Q9    814   RPGF5_MOUSE Rap guanine nucleotide exchange f...2060.00000000001     71.2     28     47GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0030742; F:GTP-dependent protein binding; ISS:UniProtKB.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
11Q8WZA2    1011   RPGF4_HUMAN Rap guanine nucleotide exchange f...2110.00000000004     70.1     27     47GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0030552; F:cAMP binding; ISS:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
12Q9EQZ6    1011   RPGF4_MOUSE Rap guanine nucleotide exchange f...1740.0000000001     68.6     27     48GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:MGI.
GO:0030552; F:cAMP binding; IDA:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
13Q02342    1095   CDC25_LACKL Cell division control protein 25 ...2200.0000000003     67     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
14Q54S40    1312   GBPD_DICDI Cyclic GMP-binding protein D OS=Di...2160.0000000004     66.6     26     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:dictyBase.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0051272; P:positive regulation of cellular component movement; TAS:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.::GO:0031275; P:regulation of lateral pseudopodium assembly; IMP:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
15A2CEA7    1244   RGRF2_DANRE Ras-specific guanine nucleotide-r...2580.0000000005     66.6     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
16Q95KH6    466   RGF1C_MACFA Ras-GEF domain-containing family ...2240.0000000005     65.9     26     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
17Q13972    1275   RGRF1_HUMAN Ras-specific guanine nucleotide-r...2350.0000000006     66.2     26     44GO:0005829; C:cytosol; ISS:HGNC.::GO:0030426; C:growth cone; ISS:HGNC.::GO:0005886; C:plasma membrane; NAS:UniProtKB.::GO:0019717; C:synaptosome; NAS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0032863; P:activation of Rac GTPase activity; ISS:HGNC.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007616; P:long-term memory; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0031175; P:neuron projection development; ISS:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0035020; P:regulation of Rac protein signal transduction; ISS:HGNC.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
18Q8N431    466   RGF1C_HUMAN Ras-GEF domain-containing family ...2240.0000000007     65.1     26     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
19Q9Z1C7    436   RPGF4_RAT Rap guanine nucleotide exchange fac...1830.0000000009     64.7     27     46GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0030424; C:axon; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0001917; C:photoreceptor inner segment; IDA:RGD.::GO:0001750; C:photoreceptor outer segment; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0030552; F:cAMP binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0007507; P:heart development; IEP:RGD.::GO:0050805; P:negative regulation of synaptic transmission; IDA:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IDA:RGD.::GO:0050773; P:regulation of dendrite development; IMP:RGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
20P27671    1262   RGRF1_MOUSE Ras-specific guanine nucleotide-r...1690.000000001     65.5     27     48GO:0005829; C:cytosol; IDA:HGNC.::GO:0030426; C:growth cone; IDA:HGNC.
GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0032863; P:activation of Rac GTPase activity; IDA:HGNC.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:MGI.::GO:0035020; P:regulation of Rac protein signal transduction; IDA:HGNC.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
21Q9D300    466   RGF1C_MOUSE Ras-GEF domain-containing family ...2240.000000002     63.9     26     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
22P43069    1333   CDC25_CANAL Cell division control protein 25 ...2190.000000002     64.3     27     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:CGD.
GO:0019933; P:cAMP-mediated signaling; IMP:CGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071333; P:cellular response to glucose stimulus; IMP:CGD.::GO:0030447; P:filamentous growth; IMP:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IGI:CGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
23P04821    1589   CDC25_YEAST Cell division control protein 25 ...1970.000000003     63.9     27     48GO:0005829; C:cytosol; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IMP:SGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0007089; P:traversing start control point of mitotic cell cycle; IMP:SGD.
24B5VMS9    1265   SDC25_YEAS6 Guanine nucleotide exchange facto...1880.00000001     62.4     26     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
25B3LTF3    1252   SDC25_YEAS1 Guanine nucleotide exchange facto...1880.00000001     62.4     26     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
26A7A0P0    1252   SDC25_YEAS7 Guanine nucleotide exchange facto...1880.00000001     62.4     26     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
27O14827    1237   RGRF2_HUMAN Ras-specific guanine nucleotide-r...2570.00000001     62     25     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
28Q5R9B2    456   RPGFL_PONPY Rap guanine nucleotide exchange f...2110.00000001     61.2     22     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
29Q8IS19    668   GEFD_DICDI Ras guanine nucleotide exchange fa...1370.00000002     61.2     30     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
30P0CF32    1253   SDC25_YEASX Guanine nucleotide exchange facto...1880.00000002     61.2     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
31P0CF34    1048   YL017_YEAST Putative guanine nucleotide excha...1850.00000002     61.2     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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